Posted by admin on Feb 28, 2021 in |
Medicinal plant identification is necessary for ensuring their efficacy and safety in the quality control of herbal products. The genus Derris belongs to the Leguminosae family. This study aimed to investigate the microscopic characteristics of selected Derris species in Thailand. Eight Derris species (D. amoena, D. elliptica, D. indica, D. malaccensis, D. recticulata, D. scandens, D. solorioides, and D. trifoliata) existing in Thailand were studied. Anatomical characteristics of the leaves were investigated by the midrib transverse section. The laminae were quantitatively investigated for the stomatal number, stomatal index, epidermal cell area, vein islet number, trichome number, and palisade ratio. Trichomes were found in 4 species (D. elliptica, D. scanden, D. amoena and D. malaccensis) which presented as unicellular non-glandular trichome on the lower epidermis. Stomatal type found in Derris species in this study was paracytic type and presented only on lower epidermis, except D. trifoliata which was found on both lower and upper epidermis. The anatomical characteristics of the midrib of eight studied Derris species were illustrated, showing the...
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Posted by admin on Feb 28, 2021 in |
Due to emergent concerns about unhealthy consequences of chemicals in the health industry, the interest towards natural and herbal substances has been growing every day. In this study, the antioxidant effect of Cassia fistula [CFF] and Cassia auriculata [CAF] extract was evaluated. Also discover wound healing activity of polyherbal formulation (CFF and CAF). The antioxidant activity of the extract was evaluated by using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity. Total phenolic content (TPC) was determined to screen the prepared extracts by using the Folin-Ciocalteu phenol reagent method. The polyherbal formulation (CFF and CAF) using the excision wound model. The CFF and CAF extracts showed variable degrees of antioxidant activity. The formulated gel accelerates the wound healing process which may be due to enhancing the cellular defense mechanisms, proliferation, suppression of inflammation, and contraction of the collagen tissue and could be delayed by reactive oxygen species or microbial infection. The results suggest that extracts have antioxidant properties, which may be a potentially promising agent and favorable for wound healing,...
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Posted by admin on Feb 28, 2021 in |
Pteris vittata L., a fern species in the Pteridoideae subfamily of Pteridaceae, is known to possess various medicinal properties. P. vittata is used as a folk medicine in the Eastern Ghats of Tamil Nadu, Western Ghats, and Vindhyan region of Madhya Pradesh, India. The present study was undertaken to evaluate antigenotoxic, antioxidant, and antiproliferative potential of P. vittata L. HPLC analysis was carried out for identification of polyphenols in n-butanol fraction of P. vittata L. (Pvitnol). The fraction significantly inhibited H2O2 and 4NQO induced genotoxicity in E. coli PQ 37 in SOS chromotest. Pvitnol fraction showed promising antioxidant potency in various in-vitro antioxidant assays viz. in DPPH, reducing power, superoxide anion scavenging, lipid peroxidation, site-specific hydroxyl scavenging, and non-site specific hydroxyl scavenging assays. Pvitnol was also effective in protecting pBR322 plasmid against damage caused by Fenton’s reagent. The antioxidant activity may in part be accountable for its antigenotoxic activity obtained in SOS chromotest. An inhibition of 74.43% was obtained in MTT assay at a concentration of 200 µg/ml in...
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Posted by admin on Feb 28, 2021 in |
Antibiotic resistance could be a natural phenomenon that occurs when an antibiotic loses its ability to control or kill the bacterial growth; in other words, the bacteria become “resistant” and still continue to multiply in the presence of therapeutic levels of an antibiotic. Nano-technology is one of the foremost active areas in modern science. Nano particles exhibit a completely new or improved particle based on the specific characteristics. Plant extracts generally have excellent potential as antimicrobial compounds against microorganisms. Thus, they can be utilized in the treatment of infectious diseases caused by resistant microbes. The current study explores the phytochemical screening of aqueous extracts of Lantana camara, which had revealed the presence of flavonoids tannins, terpenoids, saponins, steroids, and alkaloids. Formation and stability of silver and gold nanoparticles in aqueous colloidal solution are confirmed using UV-Vis spectral, FTIR, XRD, SEM and EDX analysis. The antibacterial activity of crude, ethanol, and methanol extracts and plant-mediated silver and gold nanoparticles were done. The study concludes that the crude extracts showed the...
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Posted by admin on Feb 28, 2021 in |
Pyrethroids are among the most extensively used insecticide. The widespread use of these synthetic pesticides has stimulated research into the possible existence of adverse effects related to reproductive activity. The present study was, therefore, undertaken to assess the effects of β- Cyfluthrin, a type II synthetic pyrethroid on testes, the main organ of male reproduction. Animals were divided into five groups- Group I: Control, Group II: Vehicle control (corn oil), Group III: β-Cyfluthrin treated, Group IV: Punica granatum juice, and Group V: Pesticide + Antidote (β-Cyfluthrin + Antidote) treated. β-Cyfluthrin and Punica granatum juice both were administered orally to male albino mice of Swiss strain for 21 days to evaluate the toxic alterations in gravimetric and biochemical parameters. The body weight as well as testicular weight of animals showed significant reduction after β-Cyfluthrin treatment. Also, biochemical parameters like protein content, ATPase, SDH, and ALPase activity were seen to reduce significantly. Whereas, ACPase activity was observed to increase in β-Cyfluthrin administered group. In contrast, administration of β-Cyfluthrin and PJ concomitantly...
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