Posted by admin on Apr 30, 2018 in |
Dengue fever is an important public health problem in tropical and sub-tropical Continent. Recently the number of severe forms of the disease, dengue hemorrhagic fever, and dengue shock syndrome are increased. Dengue virus, a arbo-virus responsible for dengue fever and spread through its vector, Aedes aegypti. Controlling the mosquito is the good strategy to prevent this disease. The traditional chemical pesticides used to control mosquito have many drawbacks, and natural products are more acceptable in this aspect. The bio-efficacy of ginger (Zingiber officinale) and turmeric (Curcuma longa) ethanolic leaf extract was assessed against the fourth instars larvae of Aedes aegypti, under the laboratory conditions. Both shows moderate activity against Aedes aegypti larvae. However, the combined treatment of both leaf extract (1:1) shows highest activity. Combination of 50 µgml-1 turmeric and 50 µgml-1 ginger killed all of the population within 24 h. This is an eco-friendly and low-cost approach, may use to control Aedes...
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Posted by admin on Apr 30, 2018 in |
Phenolics have been shown to attenuate the initiation and progression of cancer. Owing to the parasitic nature, mistleoes are a rich source of phenolics and flavonoids. European mistletoe (Viscum album) formulations provide the first line of treatment for cancer by stimulating the immune system and improve the quality of life. In fact, host-associated variation has been shown to affect the therapeutic potential of the V. album preparations. Leafless Mistletoe (Viscum angulatum), a hemiparasitic plant of the Western Ghats widely used in folk medicine, contains diverse phytochemicals having anti-inflammatory properties. However antioxidant and anticancer potential of Viscum angulatum is still not investigated. In the present study, we analyzed the contents of total phenolics (TPC), flavonoids (TFC), antioxidant potential and cytotoxic potential of extracts of leafless mistletoe plants parasitic on two different host trees, Olea dioica and Flacourtia indica. The whole plant of leafless Mistletoe was extracted in organic solvents (methanol and ethanol) and water (aqueous) using rotary evaporator. In the methanolic extract, TPC of plants parasitic on O. dioica was...
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Posted by admin on Apr 30, 2018 in |
This study was conducted to investigation the effect of humic acid and salicylic on oil yield and flavonoids glycoside of safflower plant (Carthamus tinctorius L.) grown in Iraq. After soil preparation the plant seeds were cultivated during winter growing seeds at 2015-2017 at Karbala region, South Baghdad in Iraq. The humic acid was applied at 1000, 2000 and 4000 mg/lit conception as organic flower fertilizes while the application of salicylic acid was used 50, 100 and 200 mg/lit. Twister application of bath humic and salicylic acids were done at vegetable growth stage all treatment were arranged by according randomized complete block design (RCBD) flower leaves or petals ethylic extract was done by used Soxhlet apparatus, the use HPLC his prefect liquid climter to determine the type and concentration of Pt flavonoids glycoside. Also the seed oil was obtained by expression mthai. The redaction were infeed to the S2 F3 treatment (100 mgl-1 of salicylic acid with 400 mgL-1 of humic acid) was gave height value of oil yield and...
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Posted by admin on Apr 30, 2018 in |
Ten, 2-substituted benzimidazole derivatives were prepared and assessed against two Gram-positive bacteria (Streptococcus mutans, Staphylococcus aureus) and two Gram-negative bacteria (Psuedomonas aeruginosa, Escherichia coli). The derivatives were obtained by the condensation of 2-((1H-benzo[d] imidazol-2-yl) thio) acetohydrazide(4) with different substituted aromatic aldehydes and their structures were characterized by FTIR, 1H NMR. The compound (E)-2-((1H– benzo [d] imidazole-2-yl) thio)- N´- (furan- 2- yl- methylene) acetohydrazide (6g) showed potent activity against both Gram-positive species (0.2-0.8 µg/ml of MIC) which was better than the standard drug Ciprofloxacin. The derivative (E)-2-((1H-benzo[d]imidazole-2-yl) thio)-N´-(4-methoxybenzylidene) acetohydrazide (6a) was evaluated for potential polymorphism by differential scanning calorimetry (DSC). It was then subjected to crystallization using different solvents. The crystal obtained from acetonitrile solvent displayed different thermal transition (240.82 °C) from that of the parent crystal (234.52...
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Posted by admin on Apr 30, 2018 in |
Background: Cancer is still a dreadful disease, the treatment ranges with difficulties like strong side effects, shortage of donor and organs. In relation, plants and its chemical properties will provide an efficient source in the innocuous treatment for cancers. Objectives: To identify and isolate bioactive compounds from Gloriosa superba tubers and Albizia amara leaves with anti-cancer property that has traditionally been suggested as an anti-proliferative agent in ethnomedicine. Design: G. superba tubers and A. amara leaves are extracted and screened qualitatively. Extracts were then tested for antioxidant by DPPH assay. Highly potential extract with antioxidant are preceded to GCMS. The compounds determined from GCMS were selected according to its non-reported bioactive information on PubChem, and preceded against Hep-G2 and A431 cancer cell by MTT assay. Result: Ethanolic extract showed high antioxidant activity in both the plant extracts, GC-MS analysis was performed with ethanolic extracts revealing ample of phytoconstituent. Six non-reported bioactive compounds were isolated and identified using GC-MS. MTT assay was performed using isolated compounds such as 3-Hydroxy-4-methoxymandelic acid,...
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