Posted by admin on May 31, 2018 in |
Objective: To assess the pattern of adverse drug reactions (ADRs) in a tertiary care hospital. Materials and methods: This study was conducted in VSS Medical College, Burla, Odisha from October 2012 to September 2014. ADRs collected from various clinical departments were compiled and analyzed for distribution of age, gender, department, drug class and organ system. Assessment of causality, severity, and preventability was done using specific scales. Results: The occurrence of ADRs was more in males compared to females in the age group 19-60 years of age. Most of the ADRs were collected from medicine department followed by dermatology and psychiatry. The skin was the most common organ system affected followed by gastrointestinal and central nervous system. Antiretroviral drugs were the most common drugs causing ADRs followed by antimicrobials and antipsychotics. Skin rashes were the most common reaction followed by vomiting and extrapyramidal symptoms (EPS). Causality assessments of ADRs were probable for 35.71 % and possible for 64.29 %. Most of the ADRs were of moderate severity (47.48 %) followed...
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Posted by admin on May 31, 2018 in |
Bioremediation is a waste management method where we can employ different types of microorganism’s to nullify the effect of pollutants from a contaminated site. In the current study the authors have carried out a three months study to find out how different bacterial strains of Bacillus licheniformis, B. substilis and pseudomonas species can be used to assess the water quality in terms of parameters like pH, dissolved oxygen, free ammonia, total ammonia and nitrite and turbidity from the discharge of common ponds. The study was carried to evaluate the physico-chemical parameters of the catla and selavathi culture ponds by applying probiotics. During the process of investigation one pond was treated with probiotics having Bacillus licheniformis, B. subtilis and Pseudomonas species and to study the efficacy of results the pond to which probiotics were not added was kept as control. The current study is aimed not only to focus on the changes in water quality but also biochemical characterization of bacterial species and to understand what concentration of the bacterial...
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Posted by admin on May 31, 2018 in |
The present study was aimed to evaluate the effectiveness of some sesame oils obtained from different cities of Yemen. Sensitivity testing against some pathogenic bacteria and fungi were studied with four types of sesame oils in the laboratory pouring aqueous extract of the sesame seeds into the wells of the culture media. Escherichia coli, Staphylococcus aureus, Salmonella typhi, Candida albicans, Aspergillus niger and Aspregillus flavus were the microorganisms used and they were identified, confirmed and obtained from the Microbiology laboratory of the Sana’a University, Yemen. The results indicated that Semsum sanani and Semsum dwaini showed more antifungal activity against Aspergillus niger and Aspergillus flavus, while Semsum shahri, Semsum hadedi, did not show any activity against pathogenic bacteria and fungi. This study suggests that the compounds found in the semsum oil can form the basis for the development of novel broad spectrum antimicrobial formulations. These results support the notion that semsum oil may have many pharmaceutical...
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Posted by admin on May 31, 2018 in |
The present study aimed to investigate the effect of two levels from (green coffee, ginseng and their combination) on nutritional and biochemical status of obese rats. Forty eight male albino rats (Sprague Dawley Strain) used in this study, the rats divided into two main groups. The first main group (6 rats) fed on basal diet (as a control negative group). The second main group (42 rats) was fed eight weeks on high fat diet HFD to induce obesity in rats. The rats in the second main group divided into seven subgroups. Subgroup (1) fed on HFD, as a control positive group. Subgroups (2 and 3) fed on HFD containing (3% and 6% ginseng), respectively. Subgroup (4 and 5) were fed on HFD containing (3% and 6% green coffee), respectively. Subgroup (6 and 7) were fed on HFD containing (3% and 6% combination of ginseng and green coffee), respectively. The experimental period lasted six weeks. Results showed that, obese rats (control positive group) recorded significant increase p˂0.5 in (body weight...
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Posted by admin on May 31, 2018 in |
Introduction: Inflammation indicates with increased levels of inflammatory markers such as CRP is common in hemodialysis patients. Higher levels of CRP is strong predictor of morbidity and mortality in dialysis patients. The aim of this study was to evaluate the effect of pentoxifylline on serum CRP levels in hemodialysis patients compared with placebo. Methods: In this randomized clinical trial, 54 patients undergoing hemodialysis were evaluated at Zahedan’s hospitals in 1393 year. Patients were randomly divided into two groups receiving pentoxifylline and placebo. CRP Levels in Patients at months zero, two and four were tested. At the end, the data were analyzed with the software SPSS Ver. 20 and Wilcoxon and chi-square test. Results: The mean age of patients was 45.9 ± 14.8 years, 25 (46.3%) of the patients were male and 29 (53.7%) were female. CRP levels Before the intervention in patients receiving pentoxifylline was 4.5 ± 4.0, two months after the intervention was 2.8 ± 1.6 and four months after the was 2.3 ± 1.3. (P=0.001) CRP levels...
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