Posted by admin on Jan 31, 2018 in |
Aim: To evaluate pediatricians’ cognizance about the use of antibiotics and dental caries. Materials and Method: 200 Pediatricians’ who were willing to participate were selected randomly from public and private medical hospitals in South India. A pretested questionnaire was distributed to the Paediatricians’ and was personally contacted to receive the responses within a week’s time. Descriptive statistics was done using SPSS version 16 (SPSS Inc., Chicago, Illinois, USA). Results: The present study showed that 63% of pediatricians believed that paediatric medicines are not sweet. 72% of them believed antibiotics are not too sweet and 31% were unaware of what sweetens antibiotics. 35% of pediatricians frequently prescribed antibiotics and 95% of them chose oral way as their route of administration. 31% of pediatricians believed antibiotics can be related to dental effects and only 19% of them recommended children to brush after oral intake of antibiotics. 63% of pediatricians revealed that children complain about the taste of antibiotics. Conclusion: The Paediatricians’ in the study did not perceive the correct relation between...
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Posted by admin on Jan 31, 2018 in |
Purpose: To study the morphological details and analyse the morphometry of the various foramens in the dry human skulls of mainly Indian population. Materials and Methods: 64 dry skulls of unknown sex and of Indian origin were used in this study which was carried out at the Department of Anatomy and forensic department of Saveetha Medical College and Hospital in the year 2016. The parameters used were incidence, longitudinal diameter, transverse diameter, distance from midline, distance from petrous apex, and distance between right and left foramen. Result: The mean sizes of the foramen ovale on the right and left sides were 7.45 x 1.1 mm and 7.61 x 1.15 mm. We found that completely ossified pterygospinous ligament passed immediately inferior to the foramen ovale and also presence of bony septa within the foramen. The foramen spinosum was present bilaterally in 90% of the skulls. The mean sizes on the right and left sides were 2.54 x 0.8 mm and 1.97 x 0.7 mm. Foramen Vesalius is one of the...
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Posted by admin on Jan 31, 2018 in |
Objective: The aim of this study is to investigate whether exposure to subclinical dose of sodium nitrite for long term can trigger histopathological changes which are able to detect by using hematoxylin and eosin stain. Sodium nitrite has various properties that make it widely used in industrial and pharmaceutical fields. Method: Three groups of mice were used in this study; the first group was administered sodium nitrite in the drinking water for six months and the second group for eighteen months meantime the third one was used as a control. Then histopathological examination was done. Results: The results revealed that there were histopathological changes in the various tissues and organs which appeared in both exposed groups. Most changes mainly reversible except few areas in the liver and no obvious carcinogenic changes were detected by hematoxylin and eosin stain. Conclusion: The ultimate conclusion obtained from this study indicated that prolonged exposure to subclinical dose of sodium nitrite induced reversible histopathological changes in different tissues and organs except few and small...
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Posted by admin on Jan 31, 2018 in |
As science encourage most of the medicinal plants as supreme source of unlimited chemical compounds which are of great interest in pharmacological preparations. The present investigation was aimed to study Nigella sativa seeds and Cassia angustifolia leaf solvent extract (petroleum ether, methanol and aqueous solutions) for phytochemical screening, GC-MS characterization, Antimicrobial and Antioxidant assay. Qualitative phytochemicals in both Nigella sativa seeds and Cassia angustifolia leaf contains high quantity (+++) of alkaloids, Carboxylic acid, Coumarins, Phenol, Resin, Saponin, and Steroid. Antimicrobial activity was determined with two gram positive (Bacillus subtilis and staphylococcus aureus) bacteria. Methanol extract of Nigella sativa seeds shown highest zone of inhibition (19.66 ± 9.29 mm) against staphylococcus aureus, Escherichia coli and klebsiella pneumonia. Petroleum ether extracts of both Nigella sativa seeds and Cassia angustifolia leaf extracts shown highest zone of inhibition against klebsiella pneumonia (20.00 ± 5.03mm and 21.66 ± 4.16 mm, respectively). From the analysis of antioxidant potential of Nigella sativa and Cassia angustifolia extracts through DPPH free radical scavenging at three different concentration (5,...
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Posted by admin on Jan 31, 2018 in |
Eleven new compounds belonging to series 7-[5-(substituted) phenyl – 4, 5-dihydro-1H-pyrazol-3-yl]-2,3-diphenyl-5H, 10H – benzo[g] quinoxaline – 5, 10 – dione (Compound 7a-k) were synthesized by multistep synthetic scheme. The newly synthesized compounds were screened for their in-vitro antimycobacterial activity against Mycobacterium tuberculosis H37Rv by L.J. Slope (Conventional) Method. Compound 7j having 4-CH3 at phenyl ring attached to 5-position of pyrazoline ring and compound 7i having 3,4-(OCH3)2 group on the above mentioned position have been observed as most and least active antimycobacterial compounds...
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