Posted by admin on Dec 31, 2017 in |
In the present study anti-inflammatory activity of ethanol extract of Beloperone plumbaginifolia whole plant were investigated. The anti-inflammatory activity of ethanol extract of whole plant of B.plumbaginifolia were evaluated by carageenan induced rat paw edema to determine its effect on acute phase of inflammation models in rats. The phytochemical screening of ethanol extract of whole plant of B. plumbaginifolia revealed the presence of alkaloid, catechin, coumarin, flavonoid, phenol, tannin, saponin, steroid, glycoside and terpenoid. Maximum inhibition (78.63%) was obtained at the dose of 400 mg/kg of B.plumbaginifolia whole plant after 3h of treatment in carrageenen induced paw edema, whereas indomethacin produced 77.34% of inhibition. The present study suggested that B.plumbaginifolia whole plant extract possess strong anti-inflammatory...
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Posted by admin on Dec 31, 2017 in |
A study was conducted to investigate the effect of different pH, on the growth and biopigment accumulation of a green alga Dunaliella salina isolates from Sambhar salt lake, Rajasthan (India). In order to monitor the impact of pH an algal samples of D. salina was exposed to different pH regimes (6 -10 pH) along with control (8.5 pH) over a period of 30 days. Set of experiments was conducted to study and evaluate the optimum growth and biopigment content for D.salina. The results of this experiment showed that optimum growth of D.salina was found at pH 8. Total chlorophyll content of the algal species decreases as the pH value was increased. While total carotenoids content of the algal species increases as the increases pH values and it was found that the green alga species changed its appearance from green to deep orange. The results indicate that algal species showed diverse response to pH...
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Posted by admin on Dec 31, 2017 in |
Antioxidants play an important role in human health protection. Many researchers and previous studies suggest that antioxidants reduce the risk for chronic diseases like cancer, diabetes, heart disease etc. Primary sources of naturally occurring antioxidants are whole grains, fruits and vegetables. Plant sourced antioxidants like Vitamin C, Vitamin E, carotenes, phenolic acids etc, have been recognized as having the potential to reduce disease risk. Most of the antioxidant compounds in a typical diet are derived from plant sources and belong to various classes of compounds with a wide variety of physical and chemical properties. 2, 2-Diphenyl-1- picrylhydrazyl (DPPH) radicals are widely used in model systems to investigate the scavenging activity of several natural phytocompounds. DPPH assay is a rapid, simple and inexpensive method to measure antioxidant capacity of plant extracts or food. It involves the use of the free radical, DPPH which is widely used to test the ability of compounds to act as free radical scavengers or hydrogen donors and to evaluate antioxidant activity. When a solution of...
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Posted by admin on Dec 31, 2017 in |
Vitex negundo, commonly called Nirgundi, is one of the widely investigated medicinal plants of India. The present study were planned to compare different parts, i.e. leaves, stems and roots of V. negundo for antianxiety activity using elevated plus maze model. Petroleum ether (60 – 80 °C), chloroform, ethanol and aqueous extracts of these parts were prepared and evaluated for anti-anxiety activity. Among the different parts compared, only the roots showed significant anti-anxiety activity. Chloroform (400 mg/kg) and ethanol (100 mg/kg) extracts of the roots showed maximum significant anti-anxiety activity, compared to that of diazepam (2...
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Posted by admin on Dec 31, 2017 in |
Prostaglandins (PG) are commonly used in neonates with cyanotic congenital heart diseases to keep the ductus arteriosus patent. The definite treatment for these conditions is surgery. It is occasionally used for longer duration (weeks to months) in preterm babies. Reversible cortical hyperostosis is a relatively recently recognized side effect of prolonged prostaglandin therapy. We describe the case of an infant presenting this complication secondary to prolonged use of PGE1, with typical and extensive radiological findings. The enzymes (prostaglandin 15-OH dehydrogenase & prostaglandin -13 reductase) that catalyze the degradation of prostaglandins are widely distributed in many vascular beds including those of the spleen, kidney, adipose tissue, intestine, liver, testicles and lungs. PGE is normally rapidly inactivated by these tissues, particularly during passage through the lungs.18 However, infants with cyanotic congenital heart diseases that cause decreased pulmonary blood flow and reduced clearance of PGE may have a higher systemic concentration of PGE. In addition, these patients often receive pharmacologic doses of PGE to maintain the patency of the ductus arteriosus. The...
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