Posted by admin on Nov 30, 2017 in |
Background: Hypercholesterolemia is rapidly becoming a worldwide epidemic that affects children and adults. Some attempt had made to generalize a relationship between hypercholesterolemia and infertility, but until now it remains scanty. Thus, the aim of the present study was initiated. Methods: Male Wistar rats were divided into four groups of six each (n=6). The first group was control and second, third and fourth groups were fed with pure cholesterol and cholic acid orally once a day for 30 days. Body weights were noted weekly. At the end of treatment duration all animals were sacrificed by cervical dislocation. Epididymis and testis were carefully removed and the organ weights were evaluated. Left epididymis was used for sperm count and sperm morphology. Blood sample were separated and used for determination of MDA level. Serum was used to determine the Total cholesterol (TC), Triglyceride (TG), HDL levels. LDL, VLDL levels were calculated. Results: Cholesterol-fed animals showed significant increases in obesity index and blood TABARS levels. TC and TG and LDL levels were also...
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Posted by admin on Nov 30, 2017 in |
Drug interaction generally refers to a modification of the expected drug response in the patient as a result of exposure of the patient to another drug or substance. Some unintentional drug interactions produce adverse reactions in the patient, whereas some drug interactions may be intentional, to provide an improved therapeutic response or to decrease adverse drug effects. They are divided into three groups depending on the underlying mechanism of interaction: pharmaceutical, pharmacokinetic or pharmacodynamic...
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Posted by admin on Nov 30, 2017 in |
A topological index is a numeric quantity associated with a graph which characterizes the topology of the graph and is invariant under graph automorphism. Topological indices such Randić, atom-bond connectivity (ABC) and geometric (GA) indices are used to predict the bioactivity of different chemical compounds. Recently, the edge version of atom-bond connectivity and geometric arithmetic indices of graph G are introduced based on the degree of an edge of line graph of G. In this paper, the closed formulas of edge version of atom-bond connectivity and geometric-arithmetic indices for V- Pantacenic nanotube are...
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Posted by admin on Nov 30, 2017 in |
Objective: To study qualitative and quantitative estimation of phytochemicals and determination of total phenol and flavonoid content in plant parts of Mimusops elengi Linn. Methods: The solvents methanol, ethanol, aqueous and petroleum ether are used for extraction of Mimusops elengi Linn. plant parts. Phytochemical screening of plant parts was carried out in all the solvents. Quantitative estimation of carbohydrate, protein and lipids was done according to the established protocol. Determination of total phenol content was carried out using Folin – Ciocalteau method and total flavonoid content using Aluminium chloride colorimetric method. Results: The result revealed the presence of carbohydrates, alkaloids, flavonoids, tannin, saponin and terpenoids etc. Total phenol content was expressed in mg of Gallic Acid Equivalent (GAE) per g of dry weight. In results it was found that petroleum ether extract shows highest phenol content 267.20 mg/g in fruits. The content of flavonoids was expressed in mg of Quercetin Equivalent (QE) per g of dry weight. It was evaluated that total flavonoid content found highest in bark 113.35...
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Posted by admin on Nov 30, 2017 in |
Cotoneaster is a plant from Rosaceae family and produces a sugary secretion (manna). Manna is the most important constituent of species of this plant. Manna consists of different types of carbohydrates, and other phytochemicals. Sugar characterization, including reducing sugar was assayed by cupric/sodium carbonate spectrophotometric method. In addition, the composition of individual sugars was also determined using high-performance liquid chromatography (HPLC) coupled with a refraction index (RI) detector, with mannitol being the most abundant sugar. Also, amount of essential microelements was determined using flame atomic absorption spectrometry. Finally, total flavonoid content in all Cotoneaster species was determined using the aluminum chloride method. According to HPLC-RI data, C. nummularioides manna has a high percentage of mannitol (88.69±0.05) and low amount of sucrose (5.37±0.01). Total reducing sugar of the C. discolor is the lowest and in C. nummularius is the highest among all mannas. The study shows differences in sugar profile, essential microelements, and total flavonoid content. Mannas from Cotoneaster species have different carbohydrate profiles and other phytochemicals and have different...
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