Posted by admin on Jan 31, 2017 in |
Saponins are the foam producing secondary metabolites of plant. They have been evaluated for a number biological activities like anticancer, anti-inflammatory, hepatoprotective, antimicrobial, antitumor, blood cholesterol lowering properties etc. In the present study we have attempted to check the role of isolated saponins from Asparagus filicinus for its hypolipidemic activity. Saponin rich fraction of Asparagus filicinus was extracted by microwave assisted extraction technique. Phytochemical analysis and characterization was performed using FTIR technique comparing it to the standard spectra of saponins. Preliminary anti hyperlipidemic activity was evaluated using Triton WR 1339 model. This experiment shows significant reduction in total cholesterol, triglycerides, LDL and HDL level in comparison with Atorvastatin standard...
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Posted by admin on Jan 31, 2017 in |
Background: Kapikacchu (Mucuna pruriens (L.) DC.) belonging to the family Fabaceae is commonly known as Velvet bean, Cowitch, Cowhage in English and Kawaanch, Kavach in Hindi. It is mainly distributed in Asia, Africa, Pacific Islands and the United State. Kapikacchu is very famous plant for its aphrodisiac effect. Traditionally it is being used as a potent antiparkinsonian, anti-inflammatory, aphrodisiac and nervine tonic. In market two types of seeds (black and white) are available and are being used simultaneously in the name of Kapikacchu. No data is yet available in context of the comparative pharmacognosy of black and white seeds of Kapikacchu. The aim of present article is to put forward the comparative pharmacognostical analysis of both types of Kapikacchu seeds. Methods: Macroscopic evaluation, microscopic evaluation, physicochemical evaluation, extractive values, phytochemical analysis, T.L.C. study were carried out using both varieties of Kapikacchu seeds and comparative data was obtained. Results: Data pertaining to the above cited evaluations was recorded for both varieties of seeds of Kapikacchu. Conclusion: All the values hence...
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Posted by admin on Jan 31, 2017 in |
The present work is undertaken with a view to harness nanotechnology as one of the most important frontier sciences for development of printing natural fabrics using the most eco-friendly dyes, i.e. natural colors. Curcuma natural dye was studied to clarify the impact of nature of nano-size color particles on size, shape, and particle distribution of the natural dye with comparative studies of the K/S and over all fastness properties of printed samples on natural fabrics (wool, silk and cotton). Results showed that the K/S values of nano samples are higher than original samples, irrespective of the nature of the fabric used and /or the concentration of the coloring matter. Alum mordant incorporated with original curcuma can be omitted, and substituted by nano-curcuma without mordant. K/S values of the pre-mordanting acquired the higher values than the simultaneous mordanting irrespective of the fabric used, or dye particles size used, or curcuma concentrations on using tannic acid mordant. Color fastness to rubbing, and perspiration properties of nano dye is better than the...
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Posted by admin on Jan 31, 2017 in |
The literature survey on 1,2,4-Triazoles and chalcone derivatives revealed that they are endowed with wide variety of biological activities. During the present investigation newer series of chalcone derivatives S-4-(isonicotinamido)-5-(phenoxymethyl) – 4H-1,2,4 triazole-3-yl-3(-4-chlorophenyl) propanethioate (7a-7f) were synthesized by coupling suitably modified 1,2,4-Triazole nucleus with appropriate aryl aldehydes. The structures of the newly synthesized compounds were established by FTIR, 1HNMR and Mass spectral analysis. All the compounds have been evaluated for in vitro antibacterial, antifungal and antitubercular activities. The compounds exhibited weak antibacterial activity only at higher concentrations. Whereas, the antifungal activity results showed that few of the compounds were able to show moderate antifungal potency. The fungi used in the anti-microbial study were found to resistant to the other compounds. The antitubercuar activity results were encouranging as the few compounds were able to possess growth inhibiting properties against the mycobacterium tested i.e the compounds 7b, 7e and 7f possessed the MIC as low as 6.25µg/ml. Even though the compounds failed to possess anti-bacterial and antifungal activity, it is quite interesting to...
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Posted by admin on Jan 31, 2017 in |
The present work was aimed to evaluate the potential protective effect of white tea’s extract against the liver injury in an experimental model of hepatotoxicity induced by HgCl2 in mice. Histopathological investigations, liver functions and flow. Cytometrical analyses were estimated. The experimental mice were divided into four groups, each of eight mice (each mouse weighed 25 – 30gm): Group 1 was served as the control group, the mice were injected i.p. with saline solution (1ml/ day). In group 2, mice were orally administered with freshly prepared aqueous. Extract of white tea (100 mg / kg / day). Mice of group 3 were i.p. injected with HgCl2 (1mg/ kg / day); The experimental periods of the mentioned three groups were lasted for fourteen days. On the other hand, mice of group 4 were injected i.p. for 14 days with HgCl2 then administered with white tea extract for another 14 days. The aspartate amino transaminase, alanine aminotransferase levels and alkaline phosphatase level are significantly lower (P<0.05) in both groups of the...
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