Posted by admin on Jan 31, 2017 in |
Pharmacists in all practice settings are in a key position to start providing care to people, who have diabetes or are at risk of developing it, or to expand and improve their care. Pharmacy programs for patients with diabetes involve activities ranging from identifying and referring at-risk patients, to supporting American Diabetes Association recognized multi-disciplinary diabetes care programs. Pharmacists can help identify patients with diabetes through screening and should target patients at high risk, people with a family history of the disease, and women with a history of gestational diabetes or who delivered a baby weighing more than nine pounds. Patient education should be provided immediately after diagnosis, at a second stage at which time a patient assessment can be performed, and at a third stage during which patients can receive continuing education to reinforce concepts and motivational boost. One of the pharmacist’s most important roles is the referral of patients to the other members of the diabetes care team. The pharmacist can play an important role in diabetes...
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Posted by admin on Jan 31, 2017 in |
N-heterocyclic compounds have extensive biological and pharmaceutical applications. 8-Hydroxyquinoline (8-HQ) also plays a significant role in many fields of life. The excellent biological significance of the 8-HQ prompted us to extend the DFT based studies. The frontier molecular orbitals (FMOs), UV-VIS and solvation model based studies remained unknown. Therefore, we intended to study the natural bond orbital, FMOs, UV-VIS, thermodynamic properties and medium influence on solvation energies, dipole moment, FT-IR and FT-Raman using polarizable continuum model (PCM) and density-based solvation model (SMD). The electronic properties of molecule were calculated by M06-2X/6-31G (d,P) and B3LYP/6-31G (d,p) level of theories. The solvent influence on the geometric parameters, FT-IR and FT-Raman were studied by B3LYP /6-31G(d) method. A good correspondence is found between the optimized parameters and the reported X-ray data. Natural bond orbital reveals that the maximum stabilization energy reached up to 39.64kJ/mol which is responsible for extra stability of the molecule. In solvated 8-HQ, a significant medium effects on FT-IR and FT-Raman intensities is observed. The intensities enhanced from gas...
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Posted by admin on Jan 31, 2017 in |
Postpartum period is an important step because the mother’s body needs to heal and recover, after pregnancy period and childbirth. So taking good care and a balanced diet in the postpartum period, plays an important role in the women’s health. Thus, training of nutrition is so necessary at this period. The aim of this study was an evaluation the effect of the pregnancy period preparation classes on the nutritional behavior of the postpartum period. This research is a semi-experimental study. 230 number of the nulliparas admitted to the health centers selected by stratified-cluster sampling method and were placed in the intervention and control groups. Classes for the intervention group were held once every one week in the eight sessions and the duration of each session, was one hour. Collection of data was conducted through questionnaires and in order to its analysis, SPSS software was used. The results for this experiment showed that the groups of intervention and control, were similar in terms of the demographic characteristics but there was...
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Posted by admin on Jan 31, 2017 in |
Uric acid is the end-product of purine metabolism and a major antioxidant in humans. Most of the uric acid produced from the catabolism is readsorbed into the blood circulation system after primary filtration and partial secretion by the kidney. Uric acid levels in physiological fluids such as plasma and urine serve as valuable indicators for certain clinical conditions. An elevated uric acid in urine or serum can affect renal function and blood pressure, which is an indicator of gout, cardiovascular and renal diseases, hypertension, etc. Low uric acid levels may be associated with molybdenum deficiency, copper toxicity and worsening of multiple sclerosis. Therefore, detection of uric acid level dissolved in human physiological fluids is indispensable for diagnosis of patients suffering from these disorders associated with altered purine biosynthesis and catabolism. In this article the studies of detection methods for uric acid in biological samples in recent years are...
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Posted by admin on Jan 31, 2017 in |
Lansoprazole a proton pump inhibitor used in the short term treatment of gastric and duodenal ulcer, reflux esophagitis, structuring and erosive esophagitis. In the present investigation an attempt has been made to enhance the solubility and dissolution rate of lansprozole by formulating it as solid dispersions with KollidonVA64, Soluplus and poly ethylene glycol 6000 by solvent evaporation method. The solid dispersions were further compressed as tablets by using superdisintegrants such as croscarmellose sodium (CCS) & crospovidone (CP). Rapid release of lansoprazole from solid dispersions was observed which was influenced by the proportion of carrier concentration. Among the solid dispersions prepared the dispersion formulated using Soluplus showed rapid drug release than kollidon & PEG 6000 containing Solid dispersions and pure drug alone. The release was found to follow the first order kinetics. Solid dispersions prepared by the solvent evaporation method were further formulated into tablets with superdisintegrants such as croscarmellose sodium, crospovidone. The dissolution rate of such tablet formulations were found to release the drug at a faster rate than...
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