Posted by admin on Jan 31, 2016 in |
Blood Pressure (BP) is defined as the product of the cardiac output (CO) and Total Peripheral Resistance (TPR).Hypertension is defined by persistent elevation of arterial blood pressure. Any drug that is indicated for decreasing/normalizing the elevated blood pressure is considered as an Anti-Hypertensive drug. Objective: To assess the utilization pattern of anti-hypertensive agents in the General Medicine department of The Oxford Medical College, Hospital and Research Center, Bangalore. Methodology: The study was Simple Prospective Observational study which was carried out for a period of six months. Results: In the study period, 200 hypertensive cases were collected. Of these, 134 (67%) were males and 66 (33%) were females who underwent anti-hypertensive therapy. Among the various anti-hypertensive drugs, only 6 major classes were used in the study sample. They were Diuretics (Ds), Calcium Channel Blockers (CCBs), Angiotensin Receptor Blockers (ARBs), Beta Adrenergic Blockers (BABs), Alpha Adrenergic Blockers (AABs) and Angiotensin Converting Enzyme Inhibitors (ACEIs). Diuretics were used the highest in 112 (40.14%) prescriptions and AABs in 7 (2.50%) prescriptions being the...
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Posted by admin on Jan 31, 2016 in |
The Vitex negundo, which is traditional Indian medicine, has been used for treatment of various diseases. A simple, sensitive, precise and accurate RP-HPLC method has been developed for the analysis of Vitex negundo L. samples and its polyherbal formulations for their Betulinic acid content. The extraction was checked using different solvents like methanol, chloroform, 95% ethanol, acetone and dichloromethane. It was found chloroform was good extraction solvent that allowed extraction of Betulinic acid with highest content. The method involves RP C18 column with methanol-acetonitrile-water (90:5:5 % v/v/v) pH 2.5 adjusted with ortho phosphoric acid as mobile phase and UV detection at 270 nm. The flow rate was 1.3 ml/min. The retention time was 2.29 min. The linearity range was 5-30 μg/ml. The method was validated for linearity range, precision, LOD, LOQ, robustness and accuracy. Mean recovery was 99.16-100.76 %. The method was successfully applied for the quantification of Betulinic acid in leaves, seeds of Vitex negundo L. and its polyherbal formulations. The results demonstrated that the content of Betulinic...
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Posted by admin on Jan 31, 2016 in |
Wheatgrass is one grass that has been demonstrated to be of particular use to humans as a nutritional source of vitamins, enzymes, minerals, trace minerals and chlorophyll in addition to its various health benefits. Wheat grass in powder form is a method for preserving wheat grass nutrients with long shelf life and use of wheat grass powder is more convenient than wheat grass juice. Objective: To estimate the antioxidant properties of wheat grass powder obtained by different drying methods. Research Design: Different drying methods used for preparation of wheat grass powder were 1) Hot air oven drying [50˚C, 6 hr and 60˚C, 5hr] 2) Microwave drying [600W, 15 min and 800 W, 10 min] 3) Vacuum oven drying [50˚C, 25kPa, 6 hr]. For estimation of the antioxidant properties of wheat grass powder samples, chlorophyll content, Total Phenol Content and % Anti-Radical Activity were measured. Result: In the quantitative analysis of antioxidant component, microwave dried wheat grass powder samples [600W, 15 min] had highest mean value of total phenol content...
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Posted by admin on Jan 31, 2016 in |
Chlorella pyrenoidosa is a fresh water microalgae used as substrate for production of value added products like biodiesel. In this investigation C.pyrenoidosa was grown for ten days in an internally illuminated bubble column photobioreactor at: 450 lux green light (495–570 nm), 480 lux red light (620–750 nm), 1663 lux blue light (450–495 nm), 1986 luxwhite light (380 to 750 nm).The results after a period of ten days of growth, showed that C.pyrenoidosa has grown better under blue light when compared to the other types of light. C.pyrenoidosa biomass produced 33.8% of lipid contentwhen grown under blue light, indicating its potential as alternative source of...
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Posted by admin on Jan 31, 2016 in |
To investigate the effects of ginger-juice (Zingiber officinale roscoe) on amphetamine-induced locomotor activity in rat. Methods: (A) Albino rats (n=6-12) were administered G.J at the single doses (4 ml/rat, p.o) as single administration (acute) and chronic treatment over period of 7 days. Following this assessment was done. Effect of treatment with G.J acutely and chronically (7days) administered, was assessed. Parameters used during assessment were locomotor activity. Results: The ginger-juice treatment of acute and chronic (4ml/rat for 7 days) and amphetamine-induced locomotor activity has not produced any effect on any parameter of the loco motor activity Conclusion: Ginger administered itself did not affect loco motor activity as well as amphetamine-induced enhancement of loco motor...
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