Posted by admin on Jan 1, 2016 in |
Type II diabetes mellitus is a serious global health problem and is associated with considerable morbidity and mortality. According to International Diabetic Federation, by 2030 there is 1 adult in 10 will have diabetes. To achieve long term glycemic control, multiple drugs including parenteral therapy with insulin and oral drugs are needed. Hyperglycemia, diabetes associated complications and co morbidities are the strong factors that favor therapeutic poly pharmacy and reduced patient adherence. Materials and methods: It was an experimental study with pre test and post test design conducted in the department of General Medicine, Govt Medical College, Kozhikode. Data were collected from OP sheets, laboratory reports and patient interview with medication adherence questionnaire. Adherence questionnaire prepared based on Morisky 8 item medication adherence questionnaire. Results: A total of 218 patients with type 2 diabetes and associated complications were enrolled into the study from January 2013 to May 2013 after signing the written consent form. Medication adherences have been improved after pharmacist intervention. Poor adherence has been reduced from 48.2%...
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Posted by admin on Jan 1, 2016 in |
Chemical protection plays a decisive role in the resistance of plants against various pathogens and their spore germination. The so-called secondary metabolites which are a characteristic feature of plants and are important to protect plants against a wide variety of microorganisms including fungi. In order to this, the present study was carried out to evaluate the antifungal potential of Bryum cellulare aqueous and ethanolic crude extracts against percentage inhibition of spore germination and hyphal length of test fungi Curvularia lunata, the causal organism of leaf spot of Zea mays. The preliminary tests showed that flavanoid, sterols and terpenoids etc are present in the test plant. Further various concentrations of crude extracts of aqueous and ethanolic form were tested against spore germination and hyphal length of C.lunata through hanging drop method. The results showed that all the extracts posses a significant antifungal potential but highest inhibition of percentage in spore germination was observed in ethanolic extract of B.cellulare. The percentage of spore germination was 60.43 and 15.20 in 10 and...
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Posted by admin on Jan 1, 2016 in |
The present study of wound healing activity of mimusops elengi linn was aimed to evaluate this activity of extract of leaves of mimusops elengi. On the basis of traditional use and literature reference, this plant was selected for wound healing activity. A meathanolic extract of leaves of mimusops elengi was examined for wound healing activity in the form of ointment in form of ointment in excision wound model. the ointment of extract of ointment showed considerable response in excision wound model in comparision of a standard drug Betadine ointment in terms of wound contract ability, wound closure time, tensile strength, dry granuloma weight, histological analysis also showed that mimusops elengi leaves extract exhibits significant wound...
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Posted by admin on Jan 1, 2016 in |
Kalanchoe genus is known for its therapeutic values. Kalanchoe pinnata (Linn.) Pers. originating from African continent is known to exhibit wound-healing, antioxidant, anticancer and hepatoprotective activities. Traditionally, it is used to treat stones of the gall bladder. Hence, determination of the phytoconstituents of the plant that are responsible for treatment of various ailments became the area under study. The plant samples were collected from Kanchipuram District, Tamil Nadu, India, to carry out various research analyses. In this study, the aqueous and solvent extracts of the plant were prepared and screened for the presence of phytocompounds by thin layer chromatography (TLC). A comparative study on both the extracts based on results obtained after TLC was made to choose the better amongst the extracts. A gas chromatographic mass spectroscopy (GC-MS) analysis of the chosen extract was performed to determine the compounds present in it. The GC-MS results obtained gave a new dimension to our research...
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Posted by admin on Jan 1, 2016 in |
To evaluate the antimicrobial activity of Octenidine (OCT) 0.1%, Chlorhexidine (CHX) 0.2% against bacterial strains of Enterococcus faecalis and Staphylococcus aureus. The strains were inoculated in 7ml of brain heart infusion broth and diluted to reach the concentration equivalent (0.5 McFarland standard). 1ml of organism suspension was contacted with 1ml of each mouthwash and was removed at time interval of 3,5 and 10 minute and plated on Brain Heart Infusion agar. After 72 hours of incubation, colony counts were measured using stereomicroscope. Kruskal Wallis test was conducted on mean number of CFU. Post-hoc tests were conducted by using the Mann Whitney U test and Duncan’s-test of multiple comparisons. The results showed that OCT 0.1% was found to be the most effective in substantially reducing total bacterial counts after 3, 5 and 10 min time interval. OCT 0.1% was found to be the most effective in substantially reducing total bacterial...
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