Posted by admin on Sep 30, 2019 in |
Metabolic syndrome, the most prevailing health concern worldwide, and their incidences are increasing at a very high rate, resulting in enormous social costs. Obesity is a measure risk factor for non-communicable disease such as cardiovascular diseases, diabetes, cancer, and inflammation-based diseases. Therapeutic strategies for managing this syndrome include synthetic drugs and surgery, which entail high costs and serious complications. Over the last decade, there has been an increase in the interest for the expansion of anti-obesity drugs, with particular attention paid to those from natural sources. Flavonoids or bioflavonoids derived from the Latin word flavus, mean yellow, and are ubiquitous in plants; these compounds are the most abundant polyphenolic compounds in the human diet and have been found to possess many beneficial effects with advantages over chemical treatments. Several clinical and research studies has suggested that flavonoids have been investigated in great depth and have shown a wide range of anti-inflammatory, anti-oxidant, anti-microbial and anti-cancer properties. Beneficial effects of dietary flavonoids on glucose homeostasis for the prevention and treatment...
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Posted by admin on Sep 30, 2019 in |
Psoriasis is autoimmune, hyperproliferative skin disease, which is affecting 2-5% of the population. Etiology of psoriasis is multi-factorial. The disease is identified as periodic recycle of events with red-scaly skin plaques. The epidemiology of Psoriasis is still unknown. From medication, this disease can only be prevented. Currently, there are many approaches to cure this disease, but still, no approach has completely cured the illness. New treatments are available for psoriasis, which are derived from biotechnology; they are known as biological drugs. The discovery of these new drugs derived from biotechnology prevents the activation of T-cells and targets cytokines. These drugs are less toxic and better functional, so patients, as well as a dermatologist, prefer the use of these biological drugs for the treatment of psoriasis over topical therapy, phototherapy, and systemic therapy. This review gives a detailed explanation of current therapies for the treatment of psoriasis and challenges associated along with...
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Posted by admin on Aug 31, 2019 in |
Albizia procera is a genus of albizia, the member of legume family (fabaceae) and subfamily Mimosoideae. Albizia procera is tree with open canopy, occurs naturally in a wide distribution from India and Myanmar through South-East Asia to Papua New Guinea and Northern Australia. On basis of our study, Albizia procera has the high economic potential to be applied in pharmaceuticals, pharmacognosy, traditional medicines, agricultures, tanning, dyeing, construction, ornamental markets, and so many researchers identified more pharmacological activities in Albizia procera were used in humans. This review presents phytochemical constituents, pharmacognostic characters, traditional uses, pharmacological and biological activities reported for the plant and it will be helpful to explore the knowledge about Albizia procera for the...
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Posted by admin on Aug 31, 2019 in |
The Increase in industrialization has raised the levels of heavy metal pollution in the country. Heavy metals are entering through the water supply, which is ultimately reaching into streams, lakes, rivers, and groundwater. So, ultimately, these heavy metals are causing environmental pollution, which is becoming a threat to humans as well as animals as the heavy metal pollution is linked with various life-threatening diseases as discussed below. It is very difficult to remove these potent and hazardous metals from the environment as they cannot be degraded chemically and biologically. Bioremediation offers an economical approach to remove these contaminants. Bioremediation uses both live microorganisms as well as plants (Phytoremediation) for the removal of heavy metals. Among toxic heavy metals, cadmium is one such metal which is harmful to flora and fauna. The study shows the present concrete scenario as well as the previous findings in this field of remediation of potent heavy metals, especially cadmium, which is very...
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Posted by admin on Aug 31, 2019 in |
Osteoarthritis is accepted as the most growing, frequent, debilitating and heterogeneous condition that worsens the quality of life globally in the elderly, affecting an estimated 10% of men and 18% of women over 60 years of age with a rise in both prevalence and incidence. At present, there is no definite cure for osteoarthritis and no effective treatments which arrest or slow its progression; however multiple numbers of treatments ranging from newly approved oral medications, topical agents, intra-articular injections to surgery exist, but these treatments are sometimes disappointing and may have a detrimental effect on health. Hence, traditional plants appear to be efficacious and safe with the anti-osteoarthritic effect that aid for greater relief of symptoms and/or disability along with highlighting various phytochemical with scientifically proven, and validated. In this present review study, an effort is made to treat OA by focusing on the clinical, scientific and mechanistic rationale for targeting inflammatory signaling pathways in OA by use of traditional...
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