Posted by admin on Oct 1, 2012 in |
Cancer is uncontrolled growth of abnormal cells in the body. The cells causing cancer are called malignant cells. There are so many means by which one can treat the cancer such as chemotherapy, radiation treatment, surgery, etc. With all these treatments there are some side effects as loss of hairs, living cells may get killed, for surgery skilled persons are required and chances of reoccurrences are high. As per those side effects there is less popularity of such drugs. To overcome these problems and side effects liposomal treatment is useful. Liposomal drugs have high encapsulation capacity, hence shows a significant anticancer activity with decreased toxicity preferentially cadiotoxicity. These liposomal treatments have great prolonged circulation as in daunorubicin and pegylated liposomal doxorubicin. This liposomal drug delivery also developed for delivery of various drugs. Further generation of drug delivery systems will include true molecular targeting, immunoliposomes and other ligand directed constructs that represent emphasize on biological components capable of tumor recognition with delivery...
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Posted by admin on Oct 1, 2012 in |
In the recent years, the use of herbal products has been increasing in developing countries. Psidium guajava Linn. (Guava) family Myrtaceae is an important dietary plant used traditionally for medicinal purpose around the world. The fruit part of the guava is used because of its food and nutritional value but other part of the guava plant are used in the traditional system due to their medicinal properties. Since each part of the guava tree possess the economic value. The pharmacological and medicinal use have demonstrated the ability of this plant to exhibit antioxidant, hepatoprotective, antiallergic, antimicrobial, anticancer, cardioprotective, antidiabetic, ant cough, antidote properties. This review delineate with intervention of Psidium guajava in the management of various...
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Posted by admin on Oct 1, 2012 in |
Diabetic cardiomyopathy is the presence of myocardial dysfunction in the absence of coronary artery disease and hypertension. Hyperglycemia seems to be central to the pathogenesis of diabetic cardiomyopathy and to trigger a series of maladaptive stimuli that result in myocardial fibrosis and collagen deposition. These processes are thought to be responsible for altered myocardial relaxation characteristics and manifest as diastolic dysfunction on imaging. Sophisticated imaging technologies also have permitted the detection of subtle systolic dysfunction in the diabetic myocardium. In the early stages, these changes appear reversible with tight metabolic control, but as the pathologic processes become organized, the changes are irreversible and contribute to an excess risk of heart failure among diabetic patients independently of common comorbidities, such as coronary artery disease and hypertension. Therapeutic agents specifically targeting processes that lead to these pathophysiologic changes are in the early stages of development. Although glycemic control and early administration of neuro-hormonal antagonists remain the cornerstones of therapeutic approaches, newer treatment targets are currently being...
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Posted by admin on Oct 1, 2012 in |
Transdermal drug delivery systems (TDDS) also commonly known as “patches” are dosage forms designed to deliver a therapeutically effective amount of drug across a patient’s skin. The therapeutic performance of a transdermal delivery system (TDS) can be affected by the quality of contact between the patch and the skin. The adhesion of the TDS to the skin is obtained by using pressure-sensitive adhesives (PSAs), which are defined as adhesives capable of bonding to surfaces with the application of light pressure. This article provides an overview of types of transdermal, the anatomical considerations and role of adhesion, the possible adhesion failure modes and how adhesion can be measured. Several in vitro techniques have been used to monitor adhesive performance such as peel adhesion, tack and shear strength. This article provides a frame work for further discussion and scientific work to improve transdermal adhesive...
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Posted by admin on Oct 1, 2012 in |
Actinidia deliciosa (A. Chev.) C. F. Liang et A. R. Ferguson is a sub-family of the genus Actinidia, which is also known as Chinese gooseberry, kiwifruit, yangtao, etc. in China, and consists of 55–60 species. The genus Actinidia is a dioecious plant and is widely distributed on the Asian continent. It is also native to China and most of the species are cultured in the southwest of China. Out of all species, only A. deliciosa is intensely cultivated all over the world. In addition, the fruit of Actinidia deliciosa has been acclaimed for its native and medicinal values. It contains several phytoconstituents belonging to category of triterpenoids, flavonoids, phenylpropanoids, quinones and steroids. The roots of Actinidia deliciosa has been used as a traditional drug in China for a long time and are reported as Chinese folk remedy for various diseases, such as hepatitis, pyorrhea, gingivitis, edema, rheumatoid arthritis, and also various forms of cancer. Kiwi fruit has been used as mild laxative and a rich source of Vitamins. The...
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