Posted by admin on Feb 1, 2010 in |
Herbs and herbal drugs have created interest among the people by its clinically proven effects like immunomodulation, adaptogenic and antimutagenic. Also, the overuse of synthetic drugs, which results in higher incidence of adverse drug reactions, has motivated humans to return to nature for safe remedies. The problem of urinary stones or calculi is a very ancient one and many remedies have been employed during the ages these stones are found in all parts of the urinary tract, the kidney, the ureters and the urinary bladder and may vary considerably in size. In the present article, an attempt has been made to emphasis on herbal option for urinary stone....
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Posted by admin on Feb 1, 2010 in |
Multiple sclerosis affects around 2.5 million people worldwide it is one of the most common neurological disorders and cause of disability of young adults, especially in Europe and North America. There is a lack of epidemiological studies from Asia where the prevalence is reported to be low, though, with the availability of more neurologists and magnetic resonance imaging, a larger number of patients are being diagnosed. MS is a slowly progressive, immunologically mediated disease of the central nervous system, characterized by inflammation and demyelination of white matter in the brain and spinal cord. A triad of symptoms clinically characterize Multiple sclerosis: changes in sensation, muscle weakness, ataxia, dysarthria, dysphagia, visual problems, fatigue, acute or chronic pain, bladder and bowel difficulties. The diagnosis of MS is made on the basis of the clinical signs and symptoms, with magnetic resonance imaging (MRI) and other laboratory tests playing a supportive role. All tests are non specific and only provide supportive evidence for diagnosis. The effective management of multiple sclerosis is complex and draws on many disciplines,...
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Posted by admin on Feb 1, 2010 in |
The antimicrobial activities of aqueous, ethanolic and petroleum ether extracts of the leaves of Basella rubra were evaluated in the present study by measuring the inhibition zones using Cup Plate Diffusion method. The inhibition zones were significantly different (P<0.001) in each plant extract. The ethanolic extract showed maximum activity with zone of inhibition (14.3±1.82 mm) against E.coli, followed by aqueous extract (13.4±1.2 mm) and petroleum ether (5.6±0.62 mm) at a concentration of 50g/ml. Ciprofloxacin was used as the standard drug having zones of inhibition(17±0.34 mm) against E.coli and 19±0.18 mm against A. niger. Microbial inhibition was in the order E.coli (12.57±0.99), A. niger (11.68±0.71), V. cholera (11.42±0.60), S. aureus (10.71±0.46), S. typhi (9.80±0.90) , respectively with all the extracts. The extracts were not able to inhibit the growth of P....
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Posted by admin on Feb 1, 2010 in |
Vasicine is a pyrralazoquinazoline monobasic alkaloid obtained from the Plant Adhatoda vasica. In the present paper, the experiment were carried out to synthesis the various analogs of Vasicine, where the five membered ring C, was converted to seven membered ring, thus producing 7,8,9,10-Tetrahydroazepino[2,1-b] quinazolin-12(6H)one (RLX), was reported to be 6-10 times more potent than aminophylline as a bronchodilatory agent. A series of new compounds were synthesized, as modification in ring A and in ring B. The resulted compounds were evaluated for the antihistaminic activity to synthesis even more potent compounds....
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Posted by admin on Feb 1, 2010 in |
Thespesia populnea is a reputed ever green tree belonging to the family malvaceae; commonly known as Indian tulip tree. The plant is distributed tropical regions and coastal forest in India. It is well known and all the parts are used in traditional system of medicine. The plant has been used as astringent, antibacterial, hepatoprotective, haemostatic, anti-diarroheal and anti-inflammatory. The shade dried bark powder of Thespesia populnea was subjected to successive extraction using the solvents (Pet. ether, chloroform, alcohol and water). The diuretic potential of various extract of the barks was assessed in albino rats. The Volume of urine, urinary concentration of Na+, K+ and Cl– ions were the parameters of the study. Fursemide (100 mg/kg) was used as standard. The extract (400 mg/kg) has shown significant increase in the volume of urine, urinary concentration of Na+, K+ and Cl–. From the present study it may be concluded that the extract possess polyphenolic compounds, carbohydrates, proteins and possess natriuretic and diuretic...
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