Posted by admin on Sep 30, 2020 in |
Penetrating biomolecules by ultrasonic techniques is an innovative and influential tool for characterizing their physicochemical properties. Peptides have been used as extensive applications in drug construction and as an ingredient in nutritional complements. An investigation based on the behavior of the promulgation of ultrasonic waves in solids and the liquid system is now rather well recognized as an effective means for scrutinizing certain physical properties of the materials. The data attained from ultrasonic proliferation parameters such as ultrasonic velocity, density, viscosity, etc. and additional variation with a concentration of one of the modules of a medium are useful in consideration of the nature of molecular interaction in terms of physical parameters. Owing to the sensitivity to very low populace densities at high energy circumstances, ultrasonic methods have been preferred and are testified to be corresponding to other techniques. An exhaustive study of literature exposes that the ternary solutions and liquid mixtures were premeditated and reported by different inventors. They testified on the nature of forces elaborate in the formation...
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Posted by admin on Sep 30, 2020 in |
Background: A gradual and continuous loss of oestrogen may place the middle age woman at the risk of getting menopause symptoms, which profoundly affects her comfort. A phytoestrogen is a natural plant hormone similar to the female hormone oestrogen. Eating dietary phytoestrogen, improve the health standard of women by producing and regulating oestrogen level in the body. Materials and Methods: A study was done to evaluate the effects of plant phytoestrogen in the form of soya milk on the quality of life of 125 healthy postmenopausal women. Following the consent process, the participants were randomly allocated into control and the intervention group. Intervention group participants received 200 mL of homemade soya milk for a period of six weeks and the control group participants did not receive any intervention. Menopause-specific quality of life questionnaire (Menqol) was used before the intervention, 6 weeks after the intervention and at 10th-week follow-up to assess the quality of life of postmenopausal women. Results: Study results revealed that there was a significant reduction in all...
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Posted by admin on Sep 30, 2020 in |
Nanosuspension consists of a submicron colloidal dispersion of pharmaceutically active ingredient particles in the liquid phase, which is stabilized by surfactant. Poor water solubility is a major problem for the manufacturing of formulation. The drug particle reduces leads to enhance the surface area as well as bioavailability. Nanosuspension prepared by way of a number of methods. Techniques such as media milling, high-pressure homogenization have been used commercially for producing Nano-suspension. Recently engineering of nanosuspension employs emulsion and microemulsion as a templet. The unique feature of Nanosuspension has enabled its use in different dosage forms and delivered by using various routes such as an oral, pulmonary, ocular, topical, and mucoadhesive hydrogel. The benefits of nanosuspensions are improved drug dispersibility and drug solubilization, improved therapeutic efficacy and reduced toxicity. Therefore, the present review described the achievements of nano-suspensions in the drug delivery system in order to enhance the solubility, stability, and bioavailability of the drugs. This review article describes the preparation methods, characterization, and applications of the...
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Posted by admin on Sep 30, 2020 in |
Gujarat has the second largest mangrove ecosystem in India, and mangrove ecosystems are known for their extreme environments and hence extremophiles that can produce novel enzymes can be found in these extreme environments. In this study, ninety-three bacterial isolates were obtained in pure cultures from soil samples collected from Kandla, Mundra and Tuna of the Kutch region of Gujarat in the winter season. These isolates were plate-screened for their ability to produce six extracellular enzyme activities using their respective methods in order to find new isolates for their possible applications. Six enzymes amylase, lipase, protease, cellulase, oxidase, and catalase were mostly present in these isolates. The isolates were also screened for their ability to produce the bioplastic Polyhydroxybutyrate (PHB). Further, these isolates were tested for their ability to survive at different salinity levels. Among the isolates, HK47, HM19, HTA1 and HT83 were the highest amylase, lipase, protease and cellulase producers respectively. Isolates HM27, HM82 and HTA2 had shown their polyenzyme activity. HT64 and HM88 were emerged as Halotolerant while...
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Posted by admin on Sep 30, 2020 in |
To examine the antioxidant property of ethanolic extract of roots of Smilax china (EESC) on Aluminium Chloride Induced oxidative stress in Wistar rats. The phytoconstituents are extracted from the roots of S. china using ethanol, by hot continuous percolation method. The rats were divided into 5 groups (6 animals/ group) and treated with EESC (150 & 300 mg/kg of body weight) and piracetam (0.5 mg/kg of body weight) for 14 days after inducing oxidative stress with AlCl3 (100 mg/ kg of body weight) for 60 days. The lipid peroxidation level (TBARS) and antioxidants activities like Superoxide dismutase (SOD), Catalase (CAT), and Glutathione (GSH) were estimated. When compared with the control group, AlCl3 induced rats showed increased TBARS and decreased antioxidant enzymes like Catalase (CAT), Superoxide dismutase (SOD) and reduced glutathione (GSH). The EESC at higher dose 300 mg/kg of body weight animals were significantly (P<0.001) reduced the TBARS and increased the antioxidant enzymes SOD, CAT, and increased GSH when compared with the control group. The present study results revealed...
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