Posted by admin on Aug 31, 2022 in |
Lavana kalpanas are pharmaceutical preparation in which the ‘Lavana’ and the selected ‘auṣadhadravyā’ are igniting together in a closed sampuṭā to obtain the drug ash as medicinal product. Nārikelā lavana, one among the lavana kalpana mentioned in Bhaiṣajyaratnāvali 30th chapter and in Rasa taraṇgiṇi14th chapter. Nārikelā lavaṇa proved to have a high amount of electrolytes like calcium and potassium, which have antacid properties. Here the common ingredient in this Kalpana is lavana, which possesses madhura–lavanarasa & śītaviryā and having pittahara property which might be the reason for the extensive use of Lavaṇa Kalpanasin pittajanyavikaras. The higher alkalinity of Nārikelā lavaṇa may also play an important role in its mode of action. Materials and Methods: Nārikelā lavana was prepared as per the reference in Rasa taraṇgiṇi, and analytical parameters were tested. The experimental study was conducted in pyloric ligated Wistar albino rats. Then the data were analyzed statistically using One Way ANOVA followed by Dunnett’s multiple “t” test as a post hoc test. Results & Discussion: The analytical parameters like...
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Posted by admin on Aug 31, 2022 in |
Background: In India, Hypertension is becoming more common and severe, and it is linked to various socio-demographic factors. Many people are ignorant of their illness’s severity and the significance of managing it due to a lack of adequate support and education. The first step in developing a preventive program for any health condition is obtaining information regarding the level of awareness. Objective: To assess the knowledge, attitude, and practice and socio-demographic factors among hypertensive patients in tertiary care teaching hospital. Materials and Methods: A prospective cross-sectional study was conducted on the sample size of 410 hypertensive patients admitted in the Medicine Unit of AH&RC during the period from February 2021 to July 2021. Socio-demographic details were collected using data collection forms. KAP scores were determined using a standardized and validated KAP questionnaire on hypertension consisting of 22 questions. Results: In our study, most of the participants were unaware of the risk factors associated with hypertension. 55% had moderate level of knowledge and same percent of participants had moderate attitude level...
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Posted by admin on Aug 31, 2022 in |
Photodermatitis had been defined within the literature after using oral dexketoprofen and different facet results as NSAIDs are also harmful for the liver. So, to triumph over such risky results, this molecule has been encapsulated with the assistance of non-ionic surfactants. Current studies supported the occasion and differentiation of transdermal proniosome-primarily based gel. The preformulation observation was completed through FTIR, and the assessment of the method through diverse parameters like PDI, zeta capacity, drug launch, encapsulation performance, and drug content material for the formulations Dt1-Dt9. The changed proniosomal gel suggests desirable balance, launch, following 0 order kinetics; most zeta strength is ± 49mv. The drug content material in the method turned inside an envisioned variety of 92-97%. The composition of the gel might be looked after as follows in relation to the viscosity of the drug: Dt3> Dt2> Dt9> Dt7> Dt4> Market gel> Dt6> Dt5> Dt1> Dt8. Span 40 & span 60 (50:50) proniosomal gel confirmed a drug launch as much as 12 h. The encapsulation performance of proniosomal...
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Posted by admin on Aug 31, 2022 in |
Dates commonly known to be khajur in urdu (Phoenix dactylifera L.). Dates fruit is one of the best foods which possesses immense nutritional values. Date flesh is low in fat and protein but rich in sugars, mainly fructose and glucose Date have low cholesterol level and contains very little fat. It consists of proteins and various kinds of vitamins such as B1, B2, B3, and B5, and A1 and C. Date are loaded with potassium and contain little sodium, which goes a long way in keeping your nervous system in order. The potassium helps to reduce cholesterol and keeps the risk of a stroke. Mainly if women eats date fruits after delivery and girls during their menstruation so it will ultimately reduces their weaknesses. From the time it was discovered, which was thousands of years ago, dates were known to have healing powers. And while science has proved that for sure, according to history, the date palm is known to have come from what is now Iraq, Egyptians were known to have made wine with...
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Posted by admin on Aug 31, 2022 in |
The Flaviviridae family of viruses includes the dengue virus (DENV) and the Zika virus (ZIKV). Which have already caused outbreaks and epidemics in a number of countries in the entire world. Dengue fever and Zika fever are two and among the most widely disseminated mosquito-borne viral illnesses in the world both of these diseases have the potential to erupt in many places of the world at the same time, and they can be lethal as well as life-threatening. Unfortunately, there isn’t a vaccine that works well enough to combat these viruses. As a result, we used an immunoinformatics method to build a multivalent and multipathogenic epitope-based vaccination that can combat both DENV and ZIKV infections at the same time in this study. ZIKV epitope QPENLEYRI and DENV epitope NKPTLDFEL docking scores of -346.10 and -379.80 were designed for a multivalent and multipathogenic vaccine that contained non-allergenic but also highly antigenic T-cell (100 percent conserved) from DENV and ZIKV...
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