Posted by admin on Jul 31, 2022 in |
For the synthesis of a series of novel Coumarin derivatives, an efficient and easy approach has been designed. 1H-NMR and Fourier Transformed Infrared (FTIR) characterize the structures of freshly synthesized compounds, which are then evaluated for antibacterial activity in vitro by calculating the zone of inhibition and minimum inhibitory concentration. The antibacterial and antifungal activity of 4-[(2-oxo-2-[5-(2-oxo-2H-chromen-3-yl)-1, 3-thiazol-2-yl] aminoethyl] amino] benzoic acid was comparable to that of ciprofloxacin and fluconazole. The reaming compounds had moderate to good...
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Posted by admin on Jul 31, 2022 in |
Pectinase is a collection of enzymes that degrade pectin into simpler compounds known as galacturonic acids. Microbes and plants largely produce pectinase, and it has a wide range of biotechnological applications in food, agriculture, industry, the environment and medicine. Fruit juices, coffee, cocoa, tea, jams and jellies are all made with pectinase in the food industry. Furthermore, pectinase, a supplemental enzyme found in animal feed, increases nutrient absorption. Pectinase has been utilized in the agricultural sector for plant virus purification, oil extraction, retting and degumming processes, and cotton fiber bio-scouring. They play a critical function in wastewater treatment by facilitating pectin breakdown in the environmental sector. Pectinases are mostly used in the wine and paper industries in the industrial sector. Pectinases are probiotic enzymes that are introduced to a variety of foods in medicine. This review aims to compile all of the accessible information on pectinase enzymes’ biotechnological applications in diverse...
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Posted by admin on Jul 31, 2022 in |
Diarrhea alters the movement of ions and water that follows an osmotic gradient and leads to Loose, watery stools, abdominal cramps, abdominal pain, fever, bloating, blood, and mucus in the stool. Numerous critical cases have been observed in both infants and adults. The main objective of this study is based on an exploration of risk factors of diarrheal infection caused in neonates by entering pathogenic Bactria. The enteric infections responsible for diarrhea are the major cause of morbidity and mortality worldwide, while 2–4 billion cases of diarrheal infections in infants occur worldwide every year. The major microbes associated with diarrheal infection belong to all the major groups, including viruses, bacteria and protozoans. Amongst various pathogenic factors, preferred bacterial pathogens have been considered as classical organisms for the study of diarrhea viz the strains of Escherichia coli for ion absorption mechanisms, Clostridium difficile and Shigella spp. as inflammatory diarrhea and Vibrio cholera for secretory diarrhea. The current study is focused on the members of Enterobacteriaceae, including the strain of E....
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Posted by admin on Jul 31, 2022 in |
To evaluate the rational drug use and efficacy evaluation of various combinations of Antihypertensive drugs commonly prescribed for the management of hypertension in CKD patients at tertiary care hospitals. This is an observational and comparative study. A randomized trial was carried out in 300 patients after obtaining the consent for 1 year in a tertiary care hospital in Mahabubnagar. The data collection form was prepared and used. This form mainly contains the patient’s demographic details and medication chart with diagnosis. Also, prescription pattern of the patient, daily usage of antihypertensive. Antihypertensive, antacids and anti-diabetics were the most prescribed drugs. A substantial number of drugs prescribed to patients with CKD were not appropriately adjusted. Inappropriate prescribing was associated with ADRS, and drug interactions. In the study, six antihypertensive combinations were observed in that CCB’s were the most frequently prescribed drug category in patients with HTN and...
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Posted by admin on Jul 31, 2022 in |
Hibiscus sabdariffa Linn is a medicinal plant commonly known as Rosella, Sorrel, Jamaica, red-Ambadi, Queensland jelly plant etc. belonging to the family Malvaceae. Since ancient times, it has played an important role in treating various diseases. It enlarges great importance for its therapeutic potential. It is native to India, tropical Africa, and many countries like Brazil, Australia, Hawaii, Florida, Philippians, Vietnam, Central America, etc. H. sabdariffa is one such plant grown as a garden plant and vegetable plant with many traditional uses. It has immense potential as a medicinal plant and also has many beneficial effects. The plant is having height of about 3.5 m tall with dark green, red steam. The leaves are 7.5 to 12.5 cm long, calyx is red colored and consists of 5 large sepals, and the fruit is a velvety capsule about 1.25-2cm long, green in color containing 5 valves each containing 3-4 seeds. The whole plant is having many pharmacological activities reported, including Antidiabetic effect, anticancer activity, hypertensive effect, hypolipidemic effect, blood pressure-lowering...
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