Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
OPTIMIZATION AND DEVELOPMENT OF BIO SYNTHETIC SILVER NANO PARTICLES OF AZURIN- AN ANTI-CANCER AGENT FROM PSEUDOMONAS AERUGINOSA
The pretentious extract of Pseudomonas aeruginosa has shown promising anticancer activity. It contains a protein called Azurin. It has a molecular weight of 14 kDa. It is soluble in water. It is a type I copper-containing protein of cupredoxin family. In this work, Pseudomonas aeruginosa MTCC strain 647 was cultivated in modified Asparagine -proline broth. An attempt was done to isolate and purify...
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OXONE AND IODOBENZENE ARE USEFUL REACTION SYSTEM FOR SYNTHESIS OF 2-AMINOTHIAZOLE DERIVATIVES FROM EASILY AVAILABLE THIOUREA AND ALKYL / ARYL KETONES
A quick one step, innovative approach for the Synthesis of 2-aminothiazole derivatives from easily available thiourea and alkyl / aryl ketones with the help of Oxone and Iodobenzene reaction system has been developed in aqueous acetonitrile solution. The developed procedure is applicable to several types of substituted 2-aminothiazole derivatives to get the corresponding products. The developed me...
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ISOLATION AND CHARACTERIZATION OF β-SITOSTEROL FROM METHANOLIC EXTRACT OF CORDIA DICHOTOMA LINN. BARK
Cordia dichotoma Linn. belonging the family Boraginaceae is locally called as Lasora in India. It is an important drug to cure diseases of the kidney, liver, spleen, heart and blood which attribute many medicinal properties in Ayurveda. The purpose of this study is to identify and characterize the bioactive principle from the bark of Cordia dichotoma Linn. Phytochemical screening methanolic extrac...
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ANTI-INFLAMMATORY ACTIVITY OF METHANOLIC EXTRACT OF ROOTS OF RUMEX OBTUSIFOLIUS
Rumex obtusifolius belong to the family Polygonaceae, it is a common wayside weed and it has a good medicinal value. In the present study, the methanolic extract (sample named as R2) of roots of R. obtusifolius was used to examine the in-vitro and in-vivo anti-inflammatory activity using human red blood cell membrane stabilization method to measure the potential of the extract on human red blood c...
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DYSLIPIDEMIC AND PROTECTIVE EFFECTS OF ASPIRIN AND CLOPIDOGREL IN OBESE RATS
Introduction: Antiplatelets play a crucial role in improving many metabolic disorders and complications, including dyslipidemia, atherosclerosis, diabetes mellitus and cardiovascular diseases. The most common and effective antiplatelets used widely are aspirin and clopidogrel. The aim of this study is to evaluate the dyslipidemic and protective effects of aspirin and clopidogrel in obese rats. Mat...
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MALDI-TOF MS BIOTYPER AND POLYMERASE CHAIN REACTION FOR RAPID IDENTIFICATION OF STAPHYLOCOCCUS AUREUS AND PSEUDOMONAS AERUGINOSA IN NON-STERILE PHARMACEUTICAL PREPARATIONS
Absence of pathogenic bacteria is a must for passing the microbiological quality control inspection of non-sterile pharmaceutical products. The identification of microbial contaminants by conventional methods is time-consuming and labor-intensive. The overall aim of the study was to test non-conventional methods as polymerase chain reaction (PCR) and Matrix Assisted Laser Desorption Ionization Tim...
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SCREENING STUDY OF THREE MEDICINAL PLANTS FOR THEIR ANTIOXIDANT AND CYTOTOXIC ACTIVITY
Plants have been used in traditional medicine for several thousand years since which may have been described to have curative value. Terminalia chebula (TC), Terminalia arjuna (TA) and Holarrhena antidysenterica (HA) are very important medicinal plants in the traditional Indian systems of Ayurveda and Siddha. In this work, fruit of Terminalia chebula, bark of Terminalia arjuna and Holarrhena antid...
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STUDY OF THE ANTI-TUMOR ACTIVITY OF SYNTHETIC PYRIDO [2,3-d]PYRIMIDINES, PYRIMIDINES AND CORRESPONDING CHALCONE DERIVATIVES
Chalcones (3a-m) was prepared by condensing 4-aminoacetophenone (1) with various aromatic aldehydes (2a-m) according to Claisen-Schmidt condensation. These 4-aminochalcones on cyclization with guanidine hydrochloride under basic alcoholic conditions gave 2,4,6-trisubstituted pyrimidines 4a-m with quantitative yields. Novel 4-amino-5,7-disubstituted pyrido[2,3-d]pyrimidines 6a-g were synthesized vi...
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ANTIBACTERIAL ACTIVITY OF RUBIA TINCTORUM LINN. ROOT EXTRACTS
This research aimed to determine the antibacterial activity of methanolic, aqueous, chloroformic and petroleum ether extracts of Rubia tinctorum roots against two gram positive and two gram negative bacteria using agar well-diffusion method. The minimum inhibitory concentration (MIC) was determined using microdilution method. Extracts were dissolved in DMSO to obtain a concentration of 10% (w/v), ...
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PHARMACOGNOSTIC STUDIES ON LEAVES AND STEMS OF IPOMOEA SEPIARIA ROXB.
Ipomoea sepiaria Roxb., also known as Purple heart glory is a slender vine belonging to family Convolvulaceae. It is one among the ten sacred plants known collectively as “Dasapushpam” in Kerala. These plants are used for rejuvenating the body in the form of ‘karkidakakanji’ in the monsoon season in Kerala. Juice of the plant is used as deobstruent, diuretic, hypotensive, uterine tonic and...
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