Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
ENHANCEMENT OF SOLUBILITY OF AN ORAL HYPOGLYCAEMIC DRUG, GLIMEPERIDE BY THE TECHNIQUE COCRYSTALLISATION
Co-crystallization is one of the most reliable alternative approaches to increase the solubility of poorly water-soluble drugs without affecting their physicochemical properties. Pharmaceutical cocrystals are neutral organic compounds connected to the API preferentially by loosely formed bonds as dipole-dipole interaction. Our present study aims at improving the solubility of an effective oral hyp...
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TO COMPARE THE EFFECTS OF DEXMEDETOMIDINE (WITHOUT BOLUS DOSE) AND PROPOFOL (SEDATIVE DOSE) ON ATTENUATION OF HEMODYNAMIC CHANGES DURING LAPAROSCOPIC SURGERIES
Introduction: Laparoscopic surgery is one of the most important diagnostic and therapeutic tools in the present surgical era. Laparoscopic surgeries require insufflation of the abdomen with some gas; usually, Carbon Dioxide is called pneumoperitonium, which induces pathophysiologic changes that complicate anesthetic management. To prevent and counteract these effects, appropriate monitoring and ph...
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PRELIMINARY PHYTOCHEMISTRY, HPTLC AND FT-IR ANALYSIS IN GLYCOSMIS PENTAPHYLLA (RETZ.) DC. – AN ETHNOBOTANICALLY IMPORTANT MEDICINAL PLANT
Medicinal plants are often used by humankind since their evolution. They are known to have prominent therapeutic potential. The present work is conducted on Glycosmis pentaphylla (Rutaceae) an ethnobotanically important medicinal plant rich in secondary metabolites. The plant possesses metabolites like alkaloids, flavonoids, terpenoids, etc., which can be used against various illnesses. The plant ...
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IN-VITRO EVALUATION OF PLEIOTROPIC PROPERTIES OF ROSUVASTATIN
Rosuvastatin, a selective and competitive inhibitor of enzyme 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase, is marked as a first-choice drug amongst lipid-lowering agents because of its unique pharmacological and pharmacokinetic properties. An additional advantage of rosuvastatin administration is its specific, non-lipid pleiotropic properties, which are considered promising new fields of rese...
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BREAKTHROUGHS IN TRANSDERMAL NANOSTRUCTURED LIPID CARRIER DRUG DELIVERY SYSTEMS
The important barrier in transdermal drug delivery (TDD) is the Stratum corneum (SC), the outermost layer of the skin, which acts as an excellent protective physiological barrier. To boost the penetration or permeation of drugs through SC, several tactics have been used including passive and active methods of permeation or both in combination. This unwraps the opportunity to broaden the range of d...
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FORMULATION AND EVALUATION OF FLOATING MICROSPHERES OF BACLOFEN
The present study was aimed to formulate and evaluate floating microspheres of Baclofen. The research work's objective was to retain Baclofen in the stomach for a prolonged period of time, which has absorption window in the upper gastrointestinal tract. The microspheres were prepared by solvent evaporation technique. A 32 full factorial was applied to investigate the combined effect of the two ind...
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PHYSICOCHEMICAL AND PHYTOCHEMICAL ANALYSIS OF METHANOLIC EXTRACT OF LEAVES AND FRUITS OF FLACOURTIA JANGOMAS (LOUR.) RAEUSCH
Plants have been used extensively as medicine for the treatment of various ailments for centuries. The present study was conducted to analyze physicochemical and phytochemical parameters of leaves and fruit of Flacourtia jangomas (Lour.) Raeusch Physicochemical profile showed the high total ash, water-soluble ash, and acid-soluble ash content in F. jangomas leaf when compared to the fruit. The w...
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FORMULATION AND STATISTICAL OPTIMIZATION OF S-SMEDDS OF NICARDIPINE HYDROCHLORIDE BY USING BBD AND PCA DESIGN
The study purpose is to further enhance the rate of dissolution for poorly water-soluble drug Nicardipine Hydrochloride by dissolving NH in surfactant, Co-surfactant, and oil; phase diagram was plotted by using oil (Capmul MM C8 EP), surfactant (Labrasol), and co-surfactant (PEG 400) through which a region called microemulsifying region was obtain. The batches were optimized by holding a 3-factor ...
1087
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SCOPE FOR HARMONISATION OF HERBAL MEDICINE REGULATIONS
Herbal Medicinal Products are gaining acceptance among people across the world due to rising awareness of lifestyle diseases and improper food habits. During the latter part of the twentieth century, increasing interest in self-care resulted in enormous growth in the popularity of traditional healing modalities, including the use of Herbal remedies. Side effects caused by the use of modern medicin...
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FORMULATION AND EVALUATION OF GASTRORETENTIVE METRONIDAZOLE TABLETS USING BRACHYSTEGIA EURYCOMA GUM
This study was conducted to evaluate gastroretentive metronidazole tablets formulated using Brachystegia eurycoma gum as a matrix. The gum was isolated from powdered dried Brachystegia eurycoma seeds. Gastroretentive metronidazole tablets were produced by direct compression technique using Brachystegia eurycoma gum, sodium carboxymethylcellulose, or their combination as the matrix. Sodium bicarbon...
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