Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.87 | 4.57 | 2.15 | 1.07 | 0.58 | 0.38 |
DEVELOPMENT AND CHARACTERIZATION OF MANNOSYLATED QUERCETIN LOADED LIPOSOMES FOR SKIN CARCINOMA
The solar UV radiation is the major trigger factor that causes skin cancer. Nearly 65% of cases of melanoma occurs dues to high exposure to the UV radiation. It also accounts for 90% of the nonmelanoma skin cancers also referred to as NMSC also including the cases of basal cell carcinoma (BCC) and the squamous cell carcinoma (SCC). The rate of malignancy in other cases has seemed to get reduced bu...
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DESIGN AND OPTIMIZATION OF EXPANDABLE GASTRORETENTIVE PATCH OF METRONIDAZOLE FOR HELICOBACTER PYLORI INFECTION MANAGEMENT
The aim of the present research was to develop and optimize novel expandable gastro retentive formulation of metronidazole to give local action for the management of Helicobacter pylori infection. The formulation contained a drug-loaded sandwich patch prepared by solvent casting method folded into a hard gelatin capsule. Metronidazole being needle shape crystals soluble in 0.1 N HCl, but after dry...
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DETERMINATION AND APPLICATION OF BIORELEVANT DISSOLUTION MEDIA TO MEET THE IN-VIVO PERFORMANCE IN VALSARTAN AND CHLORTHALIDONE IN SOLID DOSAGE FORM
Dissolution testing with biorelevant media is used in the pharmaceutical industry as a predictive tool for the estimation of drug formulation’s in-vivo performance in bioequivalence studies. The objective of this study was to determine the biorelevant dissolution media enabling the prediction of in-vivo performance of Valsartan and Chlorthalidone in solid oral dosage form as new fixed drug combi...
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IN-VITRO AND IN-VIVO ANIMAL MODEL FOR SCREENING ANTI-DIABETIC ACTIVITY OF HELLENIA SPECIOSA (J. KOENIG) S. R. DUTTA
Diabetes mellitus is one of the most common endocrine disorder which causes microvascular and macrovascular complications. Herbal medicines derived from plant extracts are used to treat various diseases because of its fewer side effects. The present investigation includes a screening of phytochemicals and evaluation of the in-vitro and in-vivo anti-diabetic activity of Hellenia speciosa leaves ext...
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CYTOTOXIC AND APOPTOGENIC EFFECTS OF A BIOACTIVE FRACTION ISOLATED FROM THE LEAVES OF A TRADITIONAL MEDICINAL PLANT TRIDAX PROCUMBENS
Objective: To investigate the anti-proliferative effects of T. procumbens leaf extracts on the growth of MCF 7, Hep G2 and K562 cells. An attempt was made to partially purify the cytotoxic acetone extract using a bioassay-guided isolation procedure and the apoptosis-inducing activity of bioactive sub-fraction, F15 (fraction 15), was probed further against K562 cells. Methods: Cytotoxicity of extra...
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ASSESSING THE EFFECT OF FARTLEK TRAINING ON PERCEIVED WELLNESS OF UNIVERSITY STUDENTS OF SAUDI ARABIA: A RANDOMIZED CONTROLLED TRIAL
Wellness is described as positive health of an individual as indicated by the quality of life and a sense of well-being. This research aimed to assess the effect of supervised fartlek training on Perceived Wellness of University Students of Saudi Arabia. A sample of forty students enrolled in various courses of KFUPM was selected for the study; the mean age was 18.52 ± 0.599 years. Two groups wer...
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TRIGONELLA FOENUM-GRAECUM L. SEED MUCILAGE-BASE MUCOADHESIVE MICROSPHERES OF DICLOFENAC SODIUM
The study was aimed to discover the properties of Trigonella foenum-graecum L. seed mucilage (TFGSM) in the formulation of mucoadhesive microspheres of diclofenac sodium to prolong the residence time at the site of absorption. Diclofenac sodium microspheres were formulated by ion gelation technique. Different polymer ratios of TFGSM and sodium alginate were used to formulate eight formulations (F1...
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PREPARATION, CHARACTERIZATION AND EVALUATION OF ANTIFUNGAL ACTIVITY OF CLOTRIMAZOLE NANOSTRUCTURED LIPID CARRIERS
Objectives: The aim of this work was the preparation of Clotrimazole (CM) loaded nanostructured lipid carriers (CM-NLC) and the examination of in-vitro antifungal activity of prepared formula. Methods: High shear hot homogenization method was used for CM-NLC preparation. Different ratios of Compritol AT 888 and Labrasol were used and combined with two types of surfactants: Kolliphor P188 or Kollip...
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SIMULTANEOUS ESTIMATION OF AMANTADINE HYDROCHLORIDE AND OSELTAMIVIR PHOSPHATE USING PRECOLUMN DERIVATIZATION TECHNIQUE
A simple, efficient HPLC method has been developed and validated for simultaneous determination of Amantadine hydrochloride and Oseltamivir phosphate using pre-column derivatization with phenyl isothiocyanate (PITC). The chromatography separation was achieved on Phenomenex C18 column of 250 × 4.6 mm 5 µm particle size, mobile phase used for chromatographic run consisted of acetonitrile and water...
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FORMULATION AND EVALUATION OF HYDROTROPIC SOLID DISPERSION OF ELUXADOLINE
In the present research, newly developed hydrotropic solid dispersion technique utilizing the use of aqueous solvent was developed, to avoid the utilization of organic solvent and all together declining their toxicity. This technology was employ intended for preparing the dispersion of Eluxadoline by using new hydrotropic agent sodium caprylate with using different ratio. Prepared formulations wer...
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