Most Cited
Year | 2020 | 2021 | 2022 | Total |
---|---|---|---|---|
No. of Published Articles | 745 | 760 | 548 | 2053 |
Citations | 699 | 263 | 21 | 983 |
Projected Impact Factor | 3.76 | 2 | 0.64 |
DEVELOPMENT AND VALIDATION OF AN UV- SPECTROPHOTOMETRIC METHOD FOR THE ESTIMATION OF FLUOXETINE IN PURE AND TABLET DOSAGE FORMS
A rapid, precise, accurate, sensitive, simple, fast and reliable spectrophotometric method has been developed for determination of Fluoxetine in bulk and pharmaceutical dosage forms. The solubility of Fluoxetine was also examined in various solvents like distilled water, methanol, ethanol, acetonitrile, HCL, chloroform etc. For the determination of working wavelength different concentrations of Fl...
4868
1227
ADDING NIACIN WITH ATORVASTATIN IN PATIENTS WITH RENAL ISCHEMIA: A COMPARATIVE STUDY
The study was aimed to compare the effect of lipid lowering only through Atorvastatin and lipid lowering combined with HDL-C raise by adding Niacin on the lipid profile and renal outcomes in renovascular disease. It was prospective, analytical hospital based study. In diagnosed patients Atorvastatin (20mg) and/or in combination with Niacin Extended Release 500mg/day was prescribed randomly distrib...
2586
996
PRELIMINARY PHYTOCHEMICAL STUDIES ON FRUITS OF TERMINALIA SPECIES (COMBRETACEAE), USED BY THE LOCAL TRIBALS OF ANDHRA PRADESH
The present paper deals with preliminary phyto-chemical screening of Terminalia species (Combretaceae), used by the local tribal communities for different human and veterinary ailments. The personal interviews conducted with local herbal practitioners and review of literature yielded 5 species of Terminalia as an effective remedy for diabetes, dysentery, diarrhoea, asthma, rheumatic pains etc. The...
2665
1055
DIABETIC NEUROPATHY: STILL A CHALLENGE IN PHARMACOLOGY.
Diabetic neuropathy is one of the most serious microvascular complications of diabetes, which appears in about 50% of the patients suffering from diabetes. It is a nerve disorder caused by diabetes, characterized usually by numbness, pain or tingling in the feet or legs, which can lead to serious problems. Patients with diabetic neuropathy suffer from various types of pain. The underlying mechanis...
3121
1075
ADAPTIVE REACTIONS INVESTIGATION UNDER EXPERIMENTAL HYPOXIA CONDITIONS WITH THE PRIOR TREATMENT OF THE 4-THIAZOLIDINONE DERIVATIVE
The effects of 4-thiazolidinone-derivative – Les-589 as perspective anti-hypoxic agent under the experimental hypoxic hypoxia actions were studied. The values of peripheral blood and hematological indexes as well as parameters of cellular oxidative metabolism (level of lipoperoxidation products, activity superoxide dismutase and catalase, levels and ratio of lactic and pyruvic acids in the blood...
2310
953
COMPARATIVE ANTIBACTERIAL STUDY OF DIFFERENT EXTRACT OF CLAVERIA ROSEA FRIES AGAINST GRAM NEGATIVE AND GRAM POSITIVE PATHOGENS
Objective: To compare the antibacterial activity of different solvent extract of Clavaria rosea. Method: Different solvent extract of Claveria rosea was prepared. Standard cultures of Escherichia coli (MTCC-1698), Klebsiella pneumoniae (MTCC-7028), Pseudomonas aeuroginosa (MTCC-1934), Salmonella typhi (MTCC-733), Xanthomonas campestris (MTCC-2286), Pseudomonas syringae (MTCC-1604) and Agrobacte...
3119
906
DESIGN AND EVALUATION OF DILTIAZEM HYDROCHLORIDE LOADED BUCCAL PATCH
The purpose of this study was to develop and optimise the formulation of mucoadhesive patches of Diltiazem hydrochloride using chitosan as base matrix. The patches were prepared by solvent casting method. PVP (K30) and propylene glycol were introduced into the patches formulae to improve the filming properties. The patches were found to be smooth in appearance, uniform in thickness, weight, and ...
2801
980
TOXICOLOGICAL ASSESSMENT OF CONSUMPTION OF BENZENE-POLLUTED WATER ON THE HEART AND BLOOD OF ALBINO RATS
The long-term effects of daily consumption of benzene-contaminated water over a period of Sixty-five days on rats’ cellular system were inspected. Haematological parameters such as haemoglobin, packed cell volume etc were determined. Standard enzyme assays were conducted on some enzymes (alkaline phosphatase, acid phosphatase and lactate dehydrogenase) activities of the heart and serum. Signific...
2626
978
PROTEIN NANOPARTICLES: FUTURE OF DRUG DELIVERY SYSTEMS
Nanoparticles have advantages, such as small size, high surface area, and modification using functional groups for high capacity or selectivity. Nanoparticles with Proteins are especially worthy of notice because they can be used for site specific targeting. Particulate systems like nanoparticles have been used as a physical approach to alter and improve the pharmacokinetic and pharmaco-dynamic pr...
5497
1525
STABILITY INDICATING METHOD DEVELOPMENT AND VALIDATION OF CHOLINE FENOFIBRATE IN PHARMACEUTICAL DOSAGE FORMS BY RP-HPLC
A simple, precise, accurate and stability indicating RP-HPLC method was developed and validated for the determination of choline fenofibrate in delayed release tablet dosage form. Separation was achieved under optimized chromatographic conditions on an inertsil ODS column (150 x 4.6 mm, 5µ particle size). The mobile phase consisted of potassium dihydrogen phosphate buffer pH 2.5 and acetonitrile ...
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