Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
THE EFFECT OF MUSA SAPIENTUM METHANOLIC FRUIT EXTRACT ON VOLUME OF GASTRIC JUICE AND PEPSIN ACTIVITY IN ASPIRIN INDUCED PEPTIC ULCERS IN ALBINO RATS
The aim of the study was to evaluate the effect of Musa sapientum methanolic fruit extract on volume of gastric juice and pepsin activity in aspirin induced peptic ulcer in albino rats. The extract was prepared by percolation method. Volume of gastric juice was estimated by the method of Deshpande SS et al (2003). Pepsin activity was studied with the methods of Debnath PK et al (1974) and Lowry OH...
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1638
DEVELOPMENT AND EVALUATION OF RANITIDINE HYDROCHLORIDE FLOATING TABLET
Floating matrix tablets of ranitidine hydrochloride were developed and evaluated to increase bioavailability by increasing gastric residence time and sustained release of drug in the upper part of gastrointestinal tract thereby diminishing side effects and enhanced patient compliance. The tablets were prepared by direct compression method, using polymers such as Hydroxy propyl methyl cellulose, ca...
6513
2097
IN-VITRO CYTOTOXIC ACTIVITY OF METHANOLIC EXTRACT OF HEMIDESMUS INDICUS R.BR.
Natural products represent a reservoir of diverse templates and are being tapped to outsource novel anticancer agents. Hemidesmus indicus R.Br.(Fam: Asclepidaceae) has been reported to be useful for the treatment of inflammation, cuts, wounds, burns, snake bite, skin and blood diseases, ulcers, immunological disorders . In the present study, the methanolic extract of the roots of Hemidesmus indicu...
4398
1620
STUDY OF ANTIULCER ACTIVITY OF ANGIOTENSIN RECEPTOR ANTAGONISTS IN EXPERIMENTALLY INDUCED GASTRIC ULCERS IN RATS
Background: Peptic ulcer is one of the common diseases affecting the mankind. Many studies reveal co-occurrence of both peptic ulcer and hypertension in humans. So, it might be beneficial to choose an optimal drug that will target both these conditions. The role of renin-angiotensin system in the pathogenesis of peptic ulcer is well known. AT receptor antagonists which prevent binding of AT-II to ...
3770
1602
POLYSACCHARIDE AS A POTENTIAL CARRIER FOR MULTIUNIT COLON SPECIFIC DRUG DELIVERY SYSTEM
In the present study maltose a polysaccharide was investigated as a promising carrier for colon specific drug delivery system. It was evaluated for pH change study, by using in-vitro and In-Vivo testing in Wistar rats. In-Vitro study shows that there is drop in the pH from 7.00 to 5.5 when incubated with ceacal content in the controlled condition. The In-Vivo experiment was carried out by admini...
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1586
AN OVERVIEW ON MICROBIAL FIBRINOLYTIC PROTEASES
Microbial fibrinolytic proteases are of considerable interest in view of their specific activity and stability at biological pH. This review describes different isolation methods which enable the screening and selection of promising organisms for industrial production. Further, strain improvement using mutagenesis and/or recombinant DNA technology can be applied to augment the efficiency of the pr...
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2172
PROTEIN NANOPARTICLES: FUTURE OF DRUG DELIVERY SYSTEMS
Nanoparticles have advantages, such as small size, high surface area, and modification using functional groups for high capacity or selectivity. Nanoparticles with Proteins are especially worthy of notice because they can be used for site specific targeting. Particulate systems like nanoparticles have been used as a physical approach to alter and improve the pharmacokinetic and pharmaco-dynamic pr...
7046
2101
DIURETIC ACTIVITY OF METHANOLIC RHIZOME EXTRACT OF PICRORRHIZA KURROA ROYLE EX. BENTH.
Kidneys are the excretory organs of our body that serves the important functions such as elimination of waste products, regulation of fluid volume and electrolyte content of the extracellular fluid. Picrorrhiza kurroa (Scrophulariaceae) is a small perennial herb growing in the hilly parts of the north-Western Himalayas region in India and Nepal. The objective of the present study was to evaluate a...
3764
1477
FORMULATION DEVELOPMENT AND QUALITY PROFILING OF PARACETAMOL – IBUPROFEN COMBINATION TABLETS
Opportunity is envisaged by some astute pharmaceuticals manufacturers to increase product portfolio and widen the spectrum of treatment of pains to cover analgesia, pyrexia and inflammation using one product. In this research work, paracetamol – ibuprofen combination tablet was designed and formulated, developed and profiled to address this anticipation thus satisfying the requirement of one pro...
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3158
PHYTOCHEMICAL STUDIES ON DELONIX ELATA BARK
Delonix elata bark was collected, authenticated, dried, coarse-finely powdered and extracted using 70% alcohol and subjected for preliminary phytochemical screening. Total phenolic and flavonoidal contents were determined using UV/ visible spectrophotometer. In addition the silica column chromatographic separation was carried out to separate the phytochemicals of D. elata bark extract. Prelimina...
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