Aim: To rationalize the macroscopial, anatomical and physico- chemical studies on leaves of Ficus benghalensis (Maraceae). Materials & methods: The crude ethanolic extract of leaves of Ficus benghalensis (Maraceae) was using Physico-chemical parameters, and Preliminary photochemical investigation (TLC, HPTLC, & Column Chrmatography). Results and conclusion: An attempt had been made to high...
DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHODS FOR ESTIMATION OF CELIPROLOL HYDROCHLORIDE IN TABLET FORMULATION
Simple, specific, accurate and cost economic UV spectrophotometric methods were developed and validated for determination of Celiprolol Hydrochloride. Instead of using organic solvents, mixture of dilute hydrochloric acid and water was used during method development and validation. The drug was extracted from tablet formulation with a mixture of water and hydrochloric acid. Stability of drug solut...
EVIDENCE BASED HOMOEOPATHY IN TREATING LONG STANDING & RECURRING VENOUS ULCER- A PROSPECTIVE AND INTERVENTIONAL STUDY
The common cause of leg ulceration in Western countries is venous disease of the lower limb.Venous insufficiency causes appreciable disability. Venous ulcer is one of the most prevalent diseases in the western countries and India, which can hamper personal and professional life of individual. After various methods of modern medicinal treatment and management there is a chance recurrence .This ca...
Curcuminoids are dietary phytochemicals obtained from dried rhizomes of turmeric plant (Curcuma longa). Curcuminoids are mixture of curcumin, demethoxy curcumin and bisdemethoxy curcumin in which curcumin is a major constituent. Several polymorphic forms of curcumin were reported. The present study relates to the preparation of different solid forms of curcuminoids and to study the influence of ot...
ANTIDIABETIC AND HAEMATOLOGICAL EFFECT OF MYRIANTHUS ARBOREUS P. BEAUV. STEM BARK EXTRACT IN STREPTOZOTOCIN – INDUCED DIABETIC RATS
The increasing prevalence of diabetes mellitus worldwide is an issue of major socio-economic concern especially in Sub - Saharan Africa. Indigenous medicinal plants are used for the treatment of diabetes mellitus in most developing countries, like Ghana, but remain to be validated. In the present study, the effect of Myrianthus arboreus ethanol stem bark extract (MAB) (100 - 400 mg/kg) on glucose ...
SYNTHESIS, CHARECTERIZATION AND ANTIMICROBIAL ACTIVITY OF 5-METHYL -2, 4-DIHYDRO-3H-PYRAZOL-3-ONE-4-(4-SUBTITUTED) BENZYLPIPERAZINE DERIVATIVES
Synthesis of 6-Methyl-2, 4-dihydro-3H-pyrazol-3-one- 4- (4-substituted) Benzylpiperazine derivatives IVP a-e was carried out by bromination of Ethyl aceto acetate (I) with KBr. The reaction was carried out in the presence of Hydrochloric acid and tolune to produce Bromo-ethyl aceto acetate (II), it is further condensed with substituted Benzylpiperazines in presence of ethanol to obtain condensed c...
A series of different 6-Methyl - 4- aryl -5 - (5-aryl -1,3,4-oxadiazole-2-yl ) -1,2,3,4-tetrahydro pyrimidin-2- (1H) - one / thione ( IIIa-g) have been synthesised fromEthyl - 6- methyl- 2- oxo / thioxo – 4-substituted phenyl-1,2,3,4-tetrahydro pyrimidine-5-carboxylate (Ia-g) followed by reaction with hydrazine hydrate in ethanol gave 6 - methyl-2-oxo / thioxo – 4 -substituted phenyl - 1,2...
GC-MS ANALYSIS OF THE CHLOROFORM EXTRACT OF BARK OF TERMINALIA TRAVANCORENSIS WIGHT & ARN. (COMBRETACEAE)
Gas Chromatography-Mass Spectrometry (GC-MS) studies play an important role in isolation and identification of phytocompounds. Since, the chemical composition of the plants usually determines its biological activity, phytochemicals of possible pharmaceutical importance can be subjected to a detailed analysis. The present study is concerned with the GC-MS analysis of chloroform extract of the bark ...
AN ANTI-DIABETIC POLY-HERBAL MEDICINE PREPARED FROM EXTRACTS OF ANNONA STENOPHYLLA, CITRUS LIMON AND ZINGIBER OFFICINALE
Background: Diabetes poses a burden on the limited health care delivery system. Current pharmacological anti-diabetic agents cause undesirable side effects and are very expensive. Herbal remedies offer the potential for alternative treatment strategies. This study was therefore conducted in an effort to formulate a poly herbal medicine for management of diabetes. Methods: A stenophylla root bark w...