Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
HERBAL BASED ANTI-MICROBIAL BOOSTER FOR THE TREATMENT OF RESISTANT MYCOBACTERIUM TUBERCULOSIS
Persistent Mycobacterium tuberculosis (Mtb) attributable to resistant strains has increased the burden leading to poor quality of life to the patients. Drugs of herbal origin have been identified as potential sources of new anti-tubercular agents for the treatment of this disease and emerging resistant strains of the bacterium. In this research, therefore, five herbs/plants that have been indicate...
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DEVELOPMENT AND VALIDATION OF QBD-ASSISTED RP-HPLC METHOD FOR DAPAGLIFLOZIN AND METFORMIN HCL IN BULK AND ITS COMBINED DOSAGE FORM
Dapagliflozin and Metformin HCl Combination is the novel SGLT2 inhibitor used to control Hyperglycemia in type 2 diabetes mellitus. A literature survey reveals that various Analytical methods have been developed for Dapagliflozin in single and combined with other drugs. No QbD-assisted RP-HPLC method is available to estimate Dapagliflozin and Metformin HCl in combination. So, present work describe...
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BACTERIOPHAGE MEDIATED MODULATION OF GUT MICROBIOME RESPONSIBLE FOR COLORECTAL CANCER
The gut microbiome composition directly correlates with the disease's development and thus with an individual's health. According to the published scientific literature, gut microbiota is directly linked with developing diseases such as colorectal cancer. On the other hand, Bacteriophages are the group of viruses that infects the bacterial cells typically and can be utilized to manage the dysbiosi...
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EVALUATION OF ANTIDIABETIC ACTIVITY OF WITHANIA COAGULANS L. DUNAL
The present study estimated the antidiabetic activity of methanolic extract of plant fruits of plant Withania coagulans L. Dunal. Withania coagulans (family Solanaceae) is commonly known as “Paneer ke phool” in Hindi and “Indian cheese maker” or “Vegetable rennet” in English, distributed in drier parts of India. The primary aim of this study was to confirm antidiabetic action of Withan...
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A COMPREHENSIVE REVIEW OF THE MEDICINAL PLANT PASSIFLORA FOETIDA LINN
Passiflora foetida, commonly known as stinking passion flower has been used as traditional medicine in treating diseases such as throat infection, giddiness, liver disorder, diarrhea, tumor, nervous disorder, anxiety; sleep disorders, skin infections, hysteria and asthma. In addition, P. foetida has been reported to have potential antioxidant, anti-inflammatory, antiepileptic, anti hyperglycemic, ...
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IN-SILICO STUDY OF ARYL SULPHONAMIDES AS 5-HT6 SEROTONIN LIGAND: A 2D QSAR STUDY USING TOPOLOGICAL DESCRIPTORS
Serotonin plays a crucial role in various cognitive and behavioral functions. The serotonin signaling is mediated by binding of serotonin to specific receptors on the cell surface. Serotonin 5-HT6 receptors turned out to be promising biological targets for the modulation of central nervous system dysfunctions. Several classes of serotonin 5-HT6 receptor ligands have been discovered. Among them, ma...
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RELATIONSHIP BETWEEN SOCIAL SKILLS AND PROBLEM BEHAVIOUR ON ACADEMIC PERFORMANCE OF THE CHILDREN WITH MILD INTELLECTUAL DISABILITY IN INCLUSIVE EDUCATION IN TRICHY DISTRICT
Background: Children with mild intellectual disabilities demonstrate wide diversity in academic and behavioural performance. They develop adequate social, personal, and communication skills. As adults, they function in a variety of contexts. Persons with moderate intellectual disabilities have limited intellectual abilities, have problems in abstracting and generalizing, and are not ready for muc...
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REVIEW OF GOUTY ARTHRITIS: A NEW PERCEPTION FOR THE TREATMENT OF OLD DISEASES
Gouty arthritis, an inflammatory joint disease, occurs due to the accumulation of Monosodium Urate (MSU) crystals in the joints, mainly at the metatarsophalangeal joints of the big toe. At present, the incidence and prevalence of gout are increasing globally. The various risk factors are responsible for the development of gouty arthritis, including nonmodifiable, modifiable, and genetic factors. U...
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INVESTIGATION OF ANTI-DEPRESSANT POTENTIAL OF 2-(4-METHYL PIPERAZIN-1-YL) ACETOHYDRAZIDE-SYNTHESIS, DFT AND DOCKING STUDY
2-(4-methyl piperazin-1-yl) acetohydrazide was synthesized. The combined practice of IR, 1H NMR, and mass spectrometry established the structure of the synthesized compound. Geometry optimization was performed using DFT at the B3LYP level, employing the basis set 6-31G (d, p). For the optimized structure, surfaces were created to study excited state properties such as electrostatic potential mappe...
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MOLECULAR DESIGN AND ANTI-BREAST CANCER ACTIVITY OF TUPICHINOL E IN HER2+ BREAST CANCER AND EGFR SENSITIZED TO OSMERTINIB THERAPY
The epidermal growth factor receptor is a tyrosine kinase receptor and its overexpression triggers cancers. EGFR inhibition is one of the most unique and popular technique for cancer treatment. There are various approved EGFR inhibitors like osmertinib, lapatinib, afatinib, etc. Huge natural products are discovered every year and Rhamnocitrin derivative Tupichinol E obtained from the Northern Sikk...
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