Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
HYDROXYCHLOROQUINE DRUG SAFETY REVIEW FOR THE PROPHYLAXIS OF SARS COV 2 PANDEMIC
COVID19 outbreak, originated from Wuhan, china is now declared as pandemic by WHO. HCQ has got special attention after various advisories are being issued by health authorities to utilize it for the prophylaxis of SARS COV2. Therefore, drug safety evaluation based on its pharmacokinetic & pharmacodynamics parameters & literature rationale for Evidence Based Medicine is required for its jus...
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SCREENING OF ANTI-BACTERIAL ACTIVITY OF BROWN SEAWEEDS FROM SOUTH EAST COAST OF INDIA
Three different species of seaweeds collected from south east coast of India such as Sargassum plagiophyllum, Padina gymnospora and Turbinaria conoides for evaluating anti-bacterial activity against selected gram-positive and gram-negative bacteria. Extracts prepared using solvents namely hexane, ethyl acetate, methanol, and water against human pathogenic strains of Proteus vulgaris, Staphylococcu...
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MANAGEMENT AGAINST COVID-19 THROUGH NUTRITIONAL SUPPLEMENTATION TO BUILD ADAPTIVE IMMUNITY – A SYSTEMATIC REVIEW
As humanity is progressing, many new borne infections are borne, and the stability and efficiency of the human body are being tested. Today the World is fighting with a deadly Novel infection named Corona Virus Disease. The aim of this systematic review is to find out the efficacy of Nutritional Interventions against the infections caused in the body due to pathogens. Further, the recommendations ...
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A STATE OF THE ART REVIEW ON SELF EMULSIFYING DRUG DELIVERY SYSTEM
Solubility plays a vital role in achieving the therapeutic efficacy of a drug from a dosage form. Advances in molecular screening techniques for identification of potential drug molecules investigated an increased number of new pharmacologically active lipophilic compounds that are poorly water-soluble about 40% of new chemical entities have been discovered as poorly water-soluble. Numbers of tech...
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ANTIDYSLIPIDEMIC AND ANTI-OXIDANT ACTIVITIES OF NIGELLA SATIVA SEEDS EXTRACT IN HYPERLIPIDEMIC RATS
This experimental study had approved by animal ethics of Central Drug Research Institute, Lucknow, and had undertaken to evaluate the antidyslipidemic and anti-oxidant activities of Nigella Sativa (N. Sativa), Hindi name Kalonji seeds extract in two models of hyperlipidemia. 1- triton and 2- cholesterol-rich high-fat diet (HFD) induced hyperlipidemia. N. Sativa and Gemfibrogil were macerated with ...
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DESIGN AND DEVELOPMENT OF SUPERPOROUS HYDROGEL OF AN ANTIHYPER-TENSIVE DRUG FOR GASTRORETENTIVE DRUG DELIVERY
Superporous hydrogels (SPHs) is originally developed as a novel drug delivery system to retain drugs in the gastric medium by instant swelling on water absorption through open porous structure and maintain their integrity in that harsh environment. Atenolol, an antihypertensive drug with a short half-life, limited bioavailability, unstable nature at basic pH potentiated the need for developing a g...
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EFFECTS OF ALLIUM SATIVUM ON BODY WEIGHT AND BIOCHEMICAL PARAMETERS IN HEALTHY RATS
This case-control study had undertaken to evaluate effect of Allium sativum in normal rats. In this study ethanol extract of Allium sativum had macerated with aqueous gum acacia (2%, w/v) suspension and fed orally (500 mg/kg b w p. o.) to male adult normal rats of charles foster strain for 15 days. Results of this study showing that alcoholic extracts caused no any significant reduction in blood g...
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IN-VITRO ANTI-INFLAMMATORY ACTIVITY, ACUTE TOXICITY TO ZEBRAFISH EMBRYOS AND NUTRITIONAL ANALYSIS OF BOHADSCHIA VITIENSIS WATER EXTRACT
Anti-inflammatory activity and the toxicity of Bohadschia vitiensis water extract were investigated by in-vitro models to evaluate the consumption of the extract by the local community to reduce arthritic-related pain. Specimens of B. vitiensis were collected from Mannar, Sri Lanka, and the water extract (WE) was prepared by removing visceral organs and incubating diced samples in distilled water,...
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UTILITY AND EFFECTIVENESS OF GENEXPERT OVER CONVENTIONAL METHODS FOR DIAGNOSIS OF PULMONARY TUBERCULOSIS
Background: Tuberculosis (TB) is a global health burden and can cause potential infection in any system of the body. Pulmonary tuberculosis (PTB) is most common presentation, but the diagnosis of TB remains elusive because of none of biochemical or serological test is invalid. During the development of END TB strategy, the gene expert (CBNAAT) test was first endorsed by WHO. Materials and Methods:...
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DESIGN AND PHARMACOKINETIC EVALUATION OF IBRUTINIB BY SELF-NANO-EMULSIFYING DRUG DELIVERY SYSTEM
The objective of present research work is design and in-vivo evaluation of ibrutinib self-nanoemulsifying drug delivery system (SNEDDS) for the enhancement of oral bioavailability. Box-Behnken design was used for the study and the results analysed using response surface methodology. Ibrutinib SNEDDS were prepared with various oils, surfactants and co-surfactants and tested particle size, PDI, zeta...
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