Aim: The aim of this review is to provide a detailed documentation and main features such as prevalance, manifestations and management regarding Kawasaki syndrome. Background: Kawasaki Syndrome was first described by Dr Tomisaku Kawasaki in Japan in 1967, since then prevalence of Kawasaki syndrome is increasing in all countries as per the reports in journals. This is more prevalent in Asian pacifi...
The aim of present study is to formulate and optimize the site specific controlled release formulation for release of loratadine in upper gastrointestinal tract. Superposrous hydrogel hybrids (SPHH) were prepared by using ferric chloride as crosslinking agent and sodium carboxymethyl cellulose as composite agent. The Superporous Hydrogels were evaluated for swelling ratio, mechanical strength, den...
SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL STUDIES OF 3-SUBSTITUTED SCHIFF BASES OF QUINAZOLINE2,4-DIONES
Objective: 3-Substituted Schiff bases of Quinazolne-2,4-diones belongs to the N-containing heterocyclic compounds. The aim of the present study is to synthesis and characterization of ten novel derivatives of 3-Substituted Schiff bases of Quinazoline2,4-diones and their pharmacological study. In the current course of work the novel Schiff bases of Quinazolne-2,4-diones which are synthesized ar...
FUNCTIONALIZATION OF THE SELECTED REGENERATED CELLULOSIC FABRICS WITH HERBAL OIL AND EVALUATE THE FUNCTIONAL PROPERTIES
In this study, an attempt has been made to approach of developing antibacterial finish using aromatic herbal oils. The five different herbal oils like Palmarosa, Petitgrain, Tea tree, Thyme, Lavender oil were screened with disc diffusion method against bacteria that normally exist like Staphylococcus aureus, Escherichia coli. The result showed good efficiency in Thyme oil when compared to other oi...
The aim of the present study was to evaluate the anxiolytic effects and motor coordination activity of Huperzine-A in rats. Wistar rats were treated orally with Huperzine-A (0.5, 1, 2 & 4 mg/kg) and diazepam (2 mg/kg p.o) as a standard anxiolytic drug then exposed to Elevated plus Maze (EPM) and Light Dark Box (LDB). The effects of the Huperzine-A on motor coordination were evaluated by actoph...
Biomarker is a measurable indicator of the severity or presence of some disease state. It is introduced into an organism as a means to examine organ function or other aspects of health. Biomarkers play a major role in medicinal biology. They help in early diagnosis, disease prevention, drug target identification, drug response etc. Several biomarkers have been identified for many diseases such as ...
Apoptosis plays an important role in development, growth, differentiation, altered gravity conditions, tissue homeostasis, immune defense, and cancer to control cell number in tissues and to eliminate individual cells that threaten the animal’s survival. The purposes of this review are to describe the signaling pathways and the cellular changes that occur with apoptosis. Currently, two pathways ...
Directly observed therapy (DOT) of tuberculosis patients talking their drugs is supposed to improve treatment completion and outcome .we compared DOT and Self Administered therapy (SAT), in which patients on the same drug regimen are not, observed taking their pills, to assess the effect of each on the success of tuberculosis treatment. This was the two year (2010 and 2011) retrospective study of ...
EVALUATION OF ANTIOXIDANT AND ANTIMICROBIAL ACTIVITY OF A MEDICINAL PLANT HYDROCOTYLE SIBTHORPIODES LAM., GROWN IN NE INDIA
The present study was conducted to evaluate the antioxidant and antibacterial activities of methanol and aqueous extracts of whole plant of Hydrocotyle sibthorpiodes Lam. Antioxidant activity was measured using reducing power, hydrogen peroxide and 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assays. The antioxidant activity was expressed as percentage (%) of DPPH and H2O2 radical...
A PRELIMINARY INVESTIGATION OF TUMOR TAKE INHIBITORY ACTIVITY OF ETHANOLIC LEAF EXTRACT OF MURRAYA KOENIGII LINN. IN MICE
The present study was undertaken to explore the tumor take inhibitory effects of ethanolic extract of Murraya koenigii in rodents. Tumor take inhibitory activity was investigated in hybrid mice (of C57BL strain + Swiss albino strain). Preventive group animals were injected daily with the extract at dose of 50mg/kg body weight i.p. for 10 consecutive days. The animals were observed for the growth o...