Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
RP-HPLC METHOD FOR QUANTIFICATION OF OROTIC ACID IN CAPSULE FORMULATION
A simple, sensitive and specific RP-HPLC method was developed and validated for the determination of Orotic acid in bulk and capsule dosage form. Chromatography was carried out on an Enable C18G (250 × 4.6 mm i.d.,5µ) column using filtered and degassed mixture of acetonitrile and methanol in the ratio of 60:40% v/v as mobile phase at a flow rate of 1 ml/min and effluent was monitored at 280 nm. ...
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A COMPARISON BETWEEN WELLS’ SCORE AND MODIFIED DOPPLER ULTRASOUND IN THE DIAGNOSIS OF DEEP VENOUS THROMBOSIS OF THE LOWER LIMB
The assessment of the probability of occurrence of deep vein thrombosis played a very important part in making a correct diagnosis and modified Wells’ score is a widely used prediction rule for pre-test probability assessment. We aimed to evaluate the diagnostic accuracy of the modified Wells’ score in the diagnosis of lower extremity deep vein thrombosis compared to Doppler ultrasound study. ...
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1324
STABILITY INDICATING UPLC METHOD FOR SIMULTANEOUS ESTIMATION OF ALBUTEROL SULPHATE, THEOPHYLLINE AND BROMHEXINE IN BULK AND COMBINED DOSAGE FORM
A new simple, precise, accurate and selective UPLC method has been developed and validated for stability indicating UPLC method for simultaneous estimation of Albuterol sulfate, Theophylline and Bromhexine HCl in the tablet dosage form. The method was carried out on a Hibra C18, 250mm x 4.6mm, 5µm. a column with a mobile phase consisting of buffer and acetonitrile and buffer in the ratio of (55: ...
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INVESTIGATION OF IN-VITRO THROMBOLYTIC AND IN-VIVO ANTIPYRETIC, ANTIDEPRESSANT POTENTIALITY AND ANALGESIC ACTIVITY WITH PHYTO-CHEMICAL NATURE OF METHANOLIC EXTRACT OF NYMPHOIDES HYDROPHYLLA
Nymphoides hydrophylla (NH) is mainly an aquatic herb of Menynthaceae family and traditionally used to treat fever, insect bites, different ulcers, and also to wash skin, where parasitic affection occurs. In this study, methanolic extract of Nymphoides hydrophylla (NH) plant was examined for the determination of thrombolytic, antipyretic, Central Nervous System (CNS) and analgesic activities. The ...
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RP-UPLC METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION AND FORCED DEGRADATION STUDIES OF ELVITEGRAVIR, COBICISTAT, EMTRICITABINE AND TENOFOVIR DISOPROXIL FUMARATE IN SOLID DOSAGE FORM
A stability indicating method was developed and validated for simultaneous estimation of Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Disoproxil Fumarate (Tenofovir D F) in solid dosage form using RP-UPLC method. Waters Acquity UPLC system with Column Endoversilo C18 (50 × 2.1 nm, 1.8 μm) having PDA detector at 252 nm wavelength was used. Mobile phase having a mixture of 700 ml of Acet...
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1423
CAPSAICIN (C18H27NO3) AND PHYTOL (C20H40O) FROM CAPSICUM ANNUM L. LEAF DOCKED AGAINST SALIVARY GLAND PROTEIN OF CULEX QUINQUEFASCIATUS
Overpopulation leads to rapid urbanization, and industrialization has directed an unplanned town expansion with no sanitary facilities and proper wastewater disposal arrangements drains in the pond. Mosquitoes create a significant public health problem in India and serve as vectors for transmitting various diseases like malaria, filariasis, dengue, chikungunya, etc., to humans. This results in the...
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DETERMINATION OF CHEMICAL COMPOSITION, TOTAL PHENOLIC CONTENT, TOTAL FLAVONOID CONTENT AND IN-VITRO ANTIOXIDANT CAPACITY OF VARIOUS ORGANIC EXTRACTS OF GYNURA CREPIOIDES LEAVES CULTIVATED IN MALAYSIA
Gynura crepioides, also known as Okinawa Spinach, belongs to the family Asteraceae, which is known to possess various medicinal properties. The present study was thus aimed at determining the GC-MS based chemical profiling, total phenolic content (TPC), total flavonoid content (TFC) and anti-oxidant (AO) capacity of the organic crude extracts such as hexane, chloroform-ethyl acetate, obtained from...
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COMPARATIVE EVALUATION OF ANTIDEPRESSANT ACTIVITY OF VARIOUS EXTRACTS OF NYCTANTHES ARBOR-TRISTIS
The present study evaluates the antidepressant activity of Nyctanthes arbor-tristis (NT). In the present study antidepressant effects of hydroalcoholic leaf extract (250 & 500 mg/kg) (NTL), flower extract (250 & 500 mg/kg) (NTF) and combination extract (leaf+flower extract in equal ratio) (250 & 500 mg/kg) (NTC) of Nyctanthes arbor-tristis were evaluated by the use of forced swim test....
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ANTI-OXIDATIVE, ANTIBACTERIAL ACTIVITY AND PHYTOCHEMICAL SCREENING OF ARTOCARPUS HETEROPHYLLUS SEED EXTRACTS
Artocarpus heterophyllus is an evergreen tree cultivated and consumed throughout Nepal; however, its seed has been neglected as compared to the fruit. The sample was screened for phytochemical evaluation, and general tests, DPPH activity, antibacterial activity, and total flavonoid content was also measured. Also, the potential of its use as functional food was highlighted. Phytochemical analysis ...
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STEROL COMPOSITION AND ANTI-ATHEROSCLEROSIS EFFECTS OF XESTOSPONGIA MUTA EXTRACTS BY INCREASING TRANSCRIPTIONAL ACTIVITY OF SR-B1 PROMOTER
Methanolic crude extract, diethyl ether fraction and sterol composition of Xestospongia muta were screened for cytotoxicity activity against HepG2 (liver hepatocellular) cells by MTS assay. Potential sterol mixture was profile using Gas Chromatography-Mass Spectrometry (GC-MS analysis), and luciferase assay were performed to further analyze its potentially on anti-atherosclerosis effects by increa...
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