Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
COMPARISON OF EIGHT METHODS FOR ESTIMATION OF CREATININE CLEARANCE IN MALAYSIA PATIENTS WITH UNSTABLE KIDNEY FUNCTION – A MULTI-CENTER, PROSPECTIVE, OBSERVATIONAL STUDY
Estimation of creatinine clearance (Clcr) has long been a problem in critically ill patients with unstable kidney function. The commonly used methods like the Cockcroft-Gault method require a stable kidney function. A reliable and more accurate tool is needed to estimate Clcrto to guide drug dosage adjustment. The study aimed to compare the eight methods to estimate Clcr with measured Clcr. In add...
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ISOTINE, AN HERBAL EYEDROPS, IMPROVES CATARACT-INDUCED BLINDNESS: A RETROSPECTIVE OBSERVATIONAL STUDY
Gradual vision loss is linked to degenerative changes and cataract. The Isotine-herbal eyedrop has been clinically used for 36 years with a claim to reverse the cataract-induced visual impairment. This retrospective observational study on 308 cataract patients, registered between 2017 to 2019 at Basu Eye hospital, Bareli, UP, India, having 3 months of treatment, shows the significant therapeutic r...
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DEVELOPMENT AND CHARACTERIZATION OF SOLID LIPID NANOPARTICLES CONTAINING ANTI-FUNGAL AGENT FOR TOPICAL DELIVERY
Fungal infection is becoming more common all over the world. Oral therapy for fungal infections is linked with toxic effects, a long treatment period, and patient intolerance. In contrast, the link between topical therapy and superficial fungal infections is low drug solubility, skin irritability, and low permeability via the skin. Top topical therapy would aim to improve the penetration of poorly...
742
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MORPHOMETRY OF HUMAN SCAPULA GLENOID FOSSA AND ITS SURGICAL ANATOMY: AN OBSERVATIONAL STUDY IN EASTERN ODISHA
Introduction: Scapulae bear a shallow articular concave fossa commonly known as glenoid cavity that accommodates the head of the humerus to form a shoulder joint. The size and shape of glenoid fossa is highly variable; hence, knowledge about morphological measurements is invariably essential for surgery and artificial prosthesis pertaining to shoulder joint pathology. Aim: Glenoid fossa morphome...
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LIVER PROTECTIVE ACTIVITY OF COCCINIA GRANDIS FRUITS EXTRACT AGAINST ANTI-TUBERCULAR DRUGS INDUCED LIVER TOXICITY IN RATS
To investigate the hepatoprotective activity of Coccinia grandis fruit extract against anti-tubercular drugs induced hepatotoxicity in rats. 50% ethanolic extract of Coccinia grandis (CGE 200 and 400 mg/kg body weight) was administered daily for 9 days in experimental animals. To develop hepatotoxicity, animals were administered orally with Isoniazid (50 mg/kg, p.o.) and Rifampicin (100 mg/kg, p.o...
554
328
COMPARATIVE EVALUATION OF CONTACT ANGLES OF ROOT CANAL SEALERS TO GUTTA PERCHA- AN IN-VITRO STUDY
Adhesion of endodontic sealers to Dentine and Gutta percha (GP) provides an understanding of the interactions between the root canal wall and the core material. The interaction of Bioceramic sealers has been studied previously but the wetability to Gutta percha has rarely been evaluated. Hence, the present in-vitro study was designed to evaluate and compare the wetability of five different root ca...
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QUANTITATIVE EVALUATION OF IMPURITIES G AND S IN VALACICLOVIR HYDROCHLORIDE HYDRATE ACTIVE PHARMACEUTICAL INGREDIENT USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY ANALYTICAL METHOD
Current work makes known that Liquid Chromatography-Mass Spectrometry (LC-MS) method development and validation for the impurity G (N, N -dimethylpyridin-4-amine) and impurity S (2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl) methoxy] ethyl N-[1,1-dimetylethoxy) carbonyl]-L-valinate) in Valaciclovir Hydrochloride Hydrate active pharmaceutical ingredient (API). The developed LC-MS analytical method i...
417
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AMELIORATION OF INFLAMMATION AND CARDIOPROTECTIVE EFFECT OF TERMINALIA ARJUNA BARK EXTRACT IN HIGH-FAT DIET RAT MODEL
The objective of this study is to investigate the protective effect of aqueous bark extract of Terminalia arjuna (TA) on high-fat diet-induced cardiovascular changes in Wistar rats using histological, immunohistochemical, and gene expression analysis. Group 1- without treatment served as control, group 2- High fat diet (HFD) received corn oil orally at a dose of 10 mL/kg, group 3 - HFD+atorvastati...
530
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SYNTHESIS OF (2, 4-DIMETHOXY – 3 – ((3 – PHENYL – 4, 5 – DIHYDROISOXAZOL – 5 – YL) METHOXY) PHENYL) (PHENYL) METHANONE AND THEIR ANTIBACTERIAL ACTIVITY
In this study, a series of novel Synthesis of (2,4-dimethoxy-3-((3- phenyl-4, 5- dihydroisoxazol-5-yl) methoxy) phenyl) (phenyl) methanone (8a-p), were synthesized from condensation of an equimolar quantity of aryl (3- hydroxy-2, 4-dimethoxyphenyl) methanones (4a-d) and 5-(bromomethyl)-3- phenyl-4,5-dihydroisoxazole (7a-d) in DMF solvent by employing anhydrous potassium carbonate (K2CO3) as a base...
432
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CHITOSAN CO-CRYSTAL FOR ENHANCING THE SOLUBITY AND DISSOLUTION RATE OF DICLOFENAC SODIUM
The present study is designed to enhance the aqueous solubility of diclofenac sodium. For the said purpose co-crystal employing chitosan with diclofenac sodium is prepared by solvent exchange. The prepared co-crystal was characterized by FTIR, DSC, XRD and TGA studies. Further, solubility, anti-inflammatory activity and in-vitro release study was determined for different batches of the formulation...
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