Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
UV-VISIBLE SPECTROPHOTOMETRIC METHOD DEVELOPMENT AND VALIDATION OF ASSAY OF PARACETAMOL TABLET FORMULATION
A novel, safe and sensitive method of spectrophotometric estimation in UV-region has been developed for the assay of paracetamol in its tablet formulation. The method have been developed and validated for the assay of paracetamol using Methanol and water as diluents. Which does not shows any interference in spectrophotometric estimations. All the parameters of the analysis were chosen according to...
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SYNTHESIS AND CHARACTERIZATION OF 3-[(5-(2-NITROPHENYL)-1, 3, 4-OXADIAZOL-2-YL) METHYL AMINO]-2-METHYL QUINAZOLIN-4(3H)-ONE
Quinazolinone is a heterocyclic chemical compound. There are two structural isomers, 2-quinazolinone and 4-quinazolinone, with the 4-isomer being the more common. The present survey aims to achieve the synthesis of quinazolinones and their derivatives of specific pharmacological properties. Various novel classes of structurally different quinazolinones have been designed and synthesized depicting ...
4019
2078
COMPUTATIONAL UNDERSTANDING OF SELECTIVE MMP INHIBITORS IN COPD
Chronic Obstructive Pulmonary Diseases (COPD) refers to multiple lung diseases, is the occurrence of chronic bronchitis and emphysema, a pair of commonly co-existing diseases of the lungs in which the airways become narrowed because of inflammatory cells like neutrophils, CD8 cells and macrophages. These cells produce the Matrix metalloproteinases (MMPs), cathapsins and other proteinase enzymes. I...
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1636
IN VITRO RELEASE KINETICS STUDY OF TRAMADOL HCl SUSTAINED RELEASE MATRIX TABLET FROM HPMC K15M
In the present study, an effort has been made to evaluate of hydroxypropyl methylcellulose HPMC K15M as rate retardant polymer to sustain the release of Tramadol HCl from Tramadol HCl sustained release tablet matrix. Different amount of HPMC K15M were used in formulation of F1 to F5 where drug and polymer ratio were consequently 5:6, 5:5, 5:4, 5:3 and 5:2 in 200 mg tablet matrix. Tablets were prep...
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1794
DETERMINATION OF DRUG SUSCEPTIBILITY PATTERN AGAINST NOSOCOMIAL INFECTION
Nosocomial infections even in this modern era antibiotics, continue to remain an important and formidable consequence of hospitalization. Our aim of the study was to investigate the antimicrobial susceptibility against hospital-associated infecting microorganisms. 30 Clinical samples were taken from OPD of GMC Hospital, Bhopal (MP), India. Among 30 clinical isolates we identified bacterial pathoge...
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1377
DESIGN AND EVALUATION OF LAMOTRIGINE ORAL SUSTAINED RELEASE TABLETS
Objective: The objective of the study is to design and evaluate oral sustained release tablet of lamotrigine using polymer such as HPMC K 4M, HPMC K 100M and methocel E50 LV at 15%, 25%, and 35% Concentration range. Methods: All the selected ingredients were weighed and passed through 40# sieve, blended in a Poly Bag except Magnesium Stearate for 10 minutes. The resultant mixture was made in to...
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1705
ANTIMICROBIAL EFFICACY OF METHANOLIC EXTRACT OF WHOLE PLANT OF NELUMBO NUCIFERA GAERTN.ANTIMICROBIAL EFFICACY OF METHANOLIC EXTRACT OF WHOLE PLANT OF NELUMBO NUCIFERA GAERTN.
The aim of the present investigation was to evaluate the antimicrobial efficacy of methanolic extract of whole plant of Nelumbo nucifera Gaertn. The methanolic extract of Nelumbo nucifera were tested for antibacterial efficacy against three gram positive bacteria & three gram negative bacteria and antifungal activity against three fungal strains by disc diffusion method. In present study Cipro...
1790
728
THE CLINICOPATHOLOGICAL BEHAVIOR AND PATTERN OF TREATMENT OF INOPERABLE ADVANCED NONSMALL CELL LUNG CANCER PATIENTS
Abstract: Lung cancer is leading cause of death due to malignancy. Non small cell lung cancer constitutes approximately 85% of all lung cancers. Despite advances in early detection of non small cell lung cancer, about 75%-80% patients with locally advanced or metastatic disease (Stage III & IV) and carries poor prognosis. Majority of these patients are not candidate for a surgical treatment. T...
4079
2006
KANENGISER’S EVALUATION METHOD: AN EFFICIENT METHOD FOR DETERMINING OCULAR IRRITANT POTENTIAL IN COSMETICS
A growing interest in usage of cosmetics has created the need for greater precision in evaluation and has stimulated research into cosmetic medicine. Ocular irritation testing represents an important step in the safety evaluation of cosmetic products. The objective of this study was to introduce a method of assessing ocular irritancy in human subjects and to illustrate the significance of a new ...
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1614
ORAL SUPPLEMENTATION WITH RUTIN, A FLAVONOL GLYCOSIDE, INHIBITS ETHANOL INDUCED HEPATIC LIPID ACCUMULATION IN EXPERIMENTAL RATS
Our aim was to determine the effect of rutin, a flavonol glycoside on ethanol induced hepatic lipid accumulation in experimental rats. Male albino Wistar rats were randomized into four groups. Groups 1 and 2 received isocaloric glucose. Hepatic injury was induced in groups 3 and 4 by administering 20% ethanol via intragastric intubation for 60days. In addition, groups 2 and 4 were given rutin (100...
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