Most Cited
Year | 2020 | 2021 | 2022 | Total |
---|---|---|---|---|
No. of Published Articles | 745 | 760 | 548 | 2053 |
Citations | 699 | 263 | 21 | 983 |
Projected Impact Factor | 3.76 | 2 | 0.64 |
DEVELOPMENT AND VALIDATION OF A METHOD FOR QUANTIFICATION OF SIPONIMOD IN SPIKED RAT PLASMA
The creation of reliable bioanalytical LC-MS (liquid chromatography-mass spectroscopy) methods is crucial for the discovery, development, and eventual marketing approval of new drugs. A brand-new medication called siponimod was developed to treat Multiple Sclerosis (MS). This medication is a sphingosine-1-phosphate (S1P) receptor modulator and is hypothesised to contribute to the reduction of MS-r...
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DEVELOPMENT AND VALIDATION OF HIGH-PERFORMANCE THIN LAYER CHROMATOGRAPHIC METHODFOR LAFUTIDINE IN BULK AND TABLET DOSAGE FORM
A simple, precise and sensitive High Performance Liquid Chromatographic method has been developed for the quantitative estimation of Lafutidinein bulk and tablet dosage form. The method was performed on Silicagel 60 F254 aluminum plate. A Camag HPTLC system comprising of Camag Linomat IV semiautomatic sample applicator, Camag TLC Scanner 3, Camag twin-trough chamber (10×10 cm) and Camag CATS 4 so...
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A COMPARATIVE STUDY OF EFFICACY AND SAFETY OF OLANZAPINE VERSUS RISPERIDONE AS AN ADJUNCT TO LITHIUM CARBONATE IN PATIENTS WITH BIPOLAR AFFECTIVE DISORDER AT A TERTIARY CARE HOSPITAL
The objective of the research was to compare the efficacy and safety of Olanzapine versus Risperidone as an add-on to Lithium carbonate in patients with bipolar affective disorder. Methods: Prospective, randomized, comparative study conducted in psychiatric Department from Nov 2018 to May 2020. 80 BPAD patients who fulfilled eligibility criteria were randomized (1:1) into two groups of 40 each rec...
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FORMULATION, OPTIMIZATION AND EVALUATION OF RESVERATROL LOADED NANOEMULSION USING RESPONSE SURFACE METHODOLOGY
Phytochemicals are intensively addressed for clinical uses, and nanostructured phytochemical delivery vehicles are on the limelight. A viable potential treatment for neurological disorders is resveratrol. In the current investigation, we sought to create a nanoemulsion containing resveratrol utilising the response surface methodology. Using Neem oil, Pluronic-f 68, and Tween 80, the effects of the...
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VALIDATION OF STABILITY INDICATING RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF AXITINIB AND AVELUMAB BY USING ANALYTICAL QUALITY BY DESIGN (AQbD) METHOD
The quantitative measurement of Axitinib and Avelumab has been created using a simple, quick, precise, sensitive, and reproducible reverse-phasehigh-performance liquid chromatography (RP-HPLC) method. It is more difficult to analyse varying amounts of pharmaceutical active medicinal ingredients in dose forms without any interferences. Therefore, the objective of the current work is to estimate Axi...
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ESTIMATION OF TARTRAZINE IN FRUIT JUICES AND JAMS BY HPTLC METHOD DEVELOPMENT AND VALIDATION PARAMETERS
Tartrazine is a lemon-yellow synthetic food colourant belonging to azo group. The Acceptable Daily Intake (ADI) of tartrazine is 7.5mg/kg However, it is possible that more than permissible amount of Tartrazine is used to make food items more attractive. This may pose threat to consumer’s health. Hence the overall aim of the study was to detect and quantitate the presence of tartrazine in commerc...
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MEDICATION ADHERENCE IN HYPERTENSIVE PATIENTS IN LUMBINI PROVINCE OF NEPAL
Medication Adherence is defined as "the extent to which a person's behavior in taking medication, lifestyle management, diet, corresponding with an agreed recommendation from a healthcare provider". Hypertension also called high blood pressure is defined as persistency with an elevation in systolic blood pressure ≥140 mmHg and /or diastolic pressure ≥ 90 mmHg. A cross-sectional study was carri...
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OPTIMIZATION AND DEVELOPMENT OF TOPICAL METAL ION – CONTAINING ANTIBACTERIAL CREAM AND GELS
Normally and often skin infections present therapeutic challenges to practitioners and researchers due to the growing concern regarding multi-drug resistant bacterial, Viral, and Fungi Strains. The Antibacterial properties of zinc sulphate and copper sulfate are well known and have been investigated for many previous years. However, the synergistic effect between both metal ions as antibacterial i...
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POTENTIAL ANTI-ULCER ACTIVITY OF SIDDHA POLY HERBAL FORMULATION PANCHA MOOLA KUDINEER CHOORANAM: INSIGHTS FROM MOLECULAR DOCKING
The Siddha medicine system, predominantly practiced in South India, encompasses a diverse range of medicinal formulations. Among them, Pancha Moola Kudineer Chooranam (PMKC) from the Therayar Maha Karisal literature is claimed to be effective against ulcers. Helicobacter pylori, causes gastric and duodenal ulcers through various transmission routes. It colonizes the duodenal epithelial cells, lead...
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CLINICOPATHOGICAL SIGNIFICANCE OF SERUM PROLACTIN, CA19-9 AND C – REACTIVE PROTEIN IN COLORECTAL CANCER
The incidence of colorectal cancer in India ranks fourth in men and third in women. Carcinogenesis is a process that involves a combination of mutations in oncogenes, tumour suppressor genes or epigenetic changes in DNA such as methylation. Our study aim to assess the clinicopathogical significance of serum Prolactin, CA19-9 and C – reactive protein in colorectal cancer. Population based case co...
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