Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
LARVICIDAL ACTIVITY OF EPALTES PYGMAEA (DC) WHOLE PLANT EXTRACTS AGAINST CULEX QUINQUEFASCIATUS SAY, AEDES AEGYPTI L. AND ANOPHELES STEPHENSI LISTON LARVAE
In the present study, the larvicidal activity of successive n-hexane, chloroform, ethyl acetate and ethanol extracts of Epaltes pygmaea DC (Family: Asteraceae) whole plant was carried out against three mosquito species namely Culex quinquefasciatus, Aedes aegypti L. and Anopheles stephensi. The crude whole plant was successively extracted with n-hexane, chloroform, ethyl acetate, and ethanol. The ...
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DEVELOPMENT OF A LIQUID ORAL IN-SITU GEL OF VORICONAZOLE FOR SUSTAINED RELEASE AND ENHANCED BIOAVAILABILITY: EQUIVALENCE TESTING USING EARTH MOVER’S DISTANCE
Development of a sustained release liquid oral in-situ gel of Voriconazole with improved bioavailability has been the main aim of this project. Complexation of the drug with hydroxypropyl beta-cyclodextrin was done to improve the solubility and stability of the drug. The mucoadhesive polymer carbopol 934P and release retardant HPMC E50 were used as factors and a two-square factorial design was emp...
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767
SALUTARY ACTIVITY OF BERBERINE AGAINST DIBUTYLTIN DICHLORIDE INDUCED ACUTE PANCREATITIS IN ALBINO WISTAR RATS
Background: Berberine is a natural alkaloid used as traditional Chinese medicine. Objective: The objective of the present study was to evaluate the effect of berberine on dibutyltin dichloride (DBTC) induced acute pancreatitis in albino Wistar rats. Methods: In this study 24 Wistar rats were randomly selected and divided into four groups. Each group consists of 6 animals. Group-1 (-ve control), Gr...
1510
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FORMULATION AND CHARACTERIZATION OF SILVER NANOPARTICLE COATED WITH NATURAL pH STIMULI POLYMER
Carboplatin is the first-line choice of drug for ovarian cancer. In this investigation, we have prepared carboplatin silver nanoparticles (CSNP’s) by electrostatic adsorption. The size range was found to be 53-87 nm and the zeta potential was in the range of -36 to -61. After coating with hyaluronic acid and drug the size was observed to be around 80 nm and zeta potential was -41. After coating ...
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CANAGLIFLOZIN SILICA LIPID HYBRID PARTICLES FOR IMPROVED SOLUBILITY AND DISSOLUTION
Silica lipid-hybrid formulations have gained an increased interest in recent times as a means to enhance the solubility as well as dissolution of poorly water-soluble lipophilic drugs. The objective of the present investigation was to design and optimize silica lipid hybrid particles of Canagliflozin to improve its solubility. Canagliflozin is an antidiabetic drug used to improve glycaemic control...
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CARDIOPROTECTIVE EFFECT OF ARBUTIN ON LIPID PEROXIDATION AND ANTIOXIDANT DEFENSE SYSTEM IN ISOPROTERENOL INDUCED MYOCARDIAL INFARCTION IN RATS
The present study was designed to investigate the cardioprotective effect of Arbutin (ARB) against isoproterenol (ISO) induced myocardial infarction (MI) in rats by studying cardiac and hepatic markers, antioxidant defense system, lipid peroxidation products and histopathological changes. Rats were pretreated with ARB (25 and 50 mg/kg BW) for 21 days. After pretreatment, ISO (60 mg/kg BW) was admi...
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STABILITY INDICATING RP-HPLC METHOD FOR THE SIMULTANEOUS DETERMINATION OF EMITRICITABINE, TENOFOVIR, COBICISTAT AND ELVITEGRAVIR
A stability-indicating RP-HPLC method for the simultaneous determination of emtricitabine (EMT), tenofovir (TNF), cobicistat (COB) and elvitegravir (ELV) in solid dosage forms. The waters 2695, High-Performance Liquid Chromatographic system with column kromasil C18, 250 × 4.6 mm, 5 µ. The detector used is PDA detector at 288 nm. The mobile phase used in this method is pH-3.5 phosphate buffer and...
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EVALUATION OF COLOUR FASTNESS PROPERTIES OF MICROBIAL PIGMENT EXTRACT FROM NOVEL SOURCES FOR TEXTILE ECOFRIENDLY DYEING & STUDY OF CIE LAB COLOUR VALUE
The pigment has acquired the greatest importance because of its excellent color value. The potential use of various carbon sources as microbial pigments for textile coloration. Flowers, leaves, fruits, vegetables, and tubers are the rich source of the secondary metabolites. In the current study, the use of microbial extract isolated from a fermentation process from 14 varieties by using Penicilliu...
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DESIGN, DEVELOPMENT AND EVALUATION OF TOPICAL ANTIINFLAMATORY HERBAL GEL
The objective of the present investigation was to develop topical curcuminoids containing gel as an anti-inflammatory. The first gel base was prepared by using various different concentrations of Carbopol 934, Propylene glycol 400, Methylparaben, Propylparaben, and required amount of distilled water. The optimized base was selected for the incorporation of different concentrations of curcuminoids ...
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NOVEL SPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS DETERMINATION OF CURCUMIN AND DICLOFENAC DIETHYLAMINE IN DEVELOPED DOSAGE FORM
Rheumatoid arthritis is an autoimmune disease that involves inflammation of joints. Diclofenac diethylamine, as well as Curcumin, are widely used for symptomatic relief of pain and inflammation. The present study was aimed at providing a simple, accurate and economical spectrophotometric method for simultaneous determination of curcumin and diclofenac diethylamine from topical gel formulation. Sim...
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