Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
ANTIDIABETIC ACTIVITY OF AVICENNIA ALBA IN STREPTOZOTOCIN INDUCED TYPE-2 DIABETIC RATS
The study was initiated to determine the antidaibetic activity of Avicennia alba in Streptozotocin induced Type-2 diabetic rats. The rats were treated with 100, 200 and 400 mg/kg of Avicennia alba stem and leaf methanolic extract (MLAA) and compared with the diabetic, normal and standard (glibenclamide) rat groups. The blood glucose levels, glycosylated haemoglobin levels, and body weight of the r...
931
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PROTECTIVE EFFECT OF CINNAMOMUM ZEYLANICUM BARK AGAINST ACETAMINOPHEN INDUCED HEPATOTOXICITY IN ALBINO RATS
The objective of the current study is to investigate the hepatoprotective activity of Cinnamomum zeylanicum bark (CZB) extract on acetaminophen-induced hepatotoxicity in albino rats. Wistar albino rats (150-200 g) of either sex were divided into six groups, and toxicity was induced by acetaminophen (APAP) at a dose of 750 mg/kg, bw, p.o, every 72 h, for two weeks. Silymarin (100 mg/kg, p.o) was gi...
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FORMULATION AND EVALUATION OF SAGO STARCH FILM CONTAINING LEVOCETIRIZINE DIHYDROCHLORIDE
Levocetirizine dihydrochloride is an orally active, third-generation non-sedative antihistamine used in the symptomatic relief of seasonal and perennial allergic rhinitis. It competes with endogenous histamine for binding at peripheral H1-receptor sites on the effector cell surface. The present work aimed to prepare mucoadhesive buccal films to deliver the drug in a controlled manner with a longer...
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EFFECTS OF POLY-UNSATURATED FATTY ACIDS ON LEUKOCYTE TELOMERE LENGTH AND INFLAMMATORY MARKERS IN D-GALACTOSE TREATED WISTAR ALBINO MALE RATS
The present study aimed at analyzing the effects of PUFA in D-galactose treated Wistar albino male rats by determining leukocyte telomere length using real-time quantitative PCR, Il-6, and high sensitive C-RP levels estimation using ELISA. D-galactose is administered for 42 days orally (100 mg/kg), and on 43rd-day, blood is collected from tail vein and plasma is separated and subjected for IL-6 an...
1081
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FABRICATION AND CHARACTERIZATION OF NANOSUSPENSION FORMULATION OF DIOSMIN FOR ENHANCED ORAL DELIVERY
Nanosuspension is a biphasic system consisting of drug particles dispersed in an aqueous surfactant or polymeric solution with a particle size between 10 to 1000 nm. Nanosuspension offers the unique advantage of increasing solubility of the pure drug resulting into faster drug absorption and hence achieving faster maximum plasma concentration. Hence, the aim of this research work was to formulate ...
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ANTIMICROBIAL ACTIVITY OF HYDRO-ALCOHOLIC BARK EXTRACT OF PONGAMIA PINNATA
Kanuga (Pongamia pinnata), a plant belonging to Leguminosae described in Vedas has ethnobotanical importance and a variety of medicinal properties. Pongamia pinnata, commonly grown on the roads of India is used to heal wounds, treat many fungal infections, skin diseases and to clean teeth. The objective of the current study is to perform phytochemical analysis and appraise the antimicrobial activi...
983
571
FORMULATION AND DEVELOPMENT OF CURCUMIN AND MAG LOADED ENTERIC COATED TABLET IN THE TREATMENT OF IBD
The incidence of Inflammatory Bowel Disease (IBD) is now rising in developing countries and increasingly considered an emerging global disease. IBD is a chronic, intermittent disease. Symptoms of IBD varies from person to person and segment of the intestinal tract involved. IBD diagnosis depends on the various test, which requires blood testing, stool testing, endoscopy, biopsies as well as physic...
1222
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PHARMACOKINETIC EVALUATION OF GENTISIC ACID IN RATS: ORAL VERSUS INTRAVENOUS ADMINISTRATION
Gentisic acid (2, 5-dihydroxybenzoic acid) is a diphenolic compound, present abundantly in natural sources. It possesses several pharmacological activities such as nephroprotective, hepatoprotective, neuroprotective, etc. However, the available literature on oral absorption of gentisic acid is scarce. Thus, the aim of the present study was to determine the pharmacokinetic parameters and bioavailab...
1173
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HYPOACIDIC ACTIVITY OF THE HERBAL EXTRACT; A STUDY ON THE INHIBITION OF PARIETAL CELL K+/H+ ATPase PUMP
Gastrointestinal tract disorders occur due to an imbalance of gastric acid secretion and defensive factors. Histamine receptor blockers and proton pump inhibitors are the most prominent therapies in the treatment of GI tract disorders. Inhibition of the K+/H+ ATPase pump blocks the secretion of gastric acid (HCl) from the parietal cells. The adverse effects of currently available drugs have oblig...
996
544
BRAIN TARGETING OF WATER SOLUBLE DRUG THROUGH NASAL ROUTE USING FATTY ACID VESICLES
Fatty acid vesicles are novel vesicles incorporating fatty acids which enhance the brain targeting efficiency when compared to conventional liposomes. This study's objective was to prepare, characterize, and evaluate fatty acid vesicles for brain targeting of a water-soluble drug, atomoxetine HCl through nasal route. The atomoxetine HCl loaded fatty acid vesicles were prepared by using the reverse...
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