Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
DEVELOPMENT AND EVALUATION OF MICROBEADS OF SIMVASTATIN LOADED WITH SODIUM ALGINATE AND ALOE VERA
Simvastatin, a lipid-lowering agent, belongs class-II drug of BCS. It has a short biological half-life (3hr), and high first-pass metabolism. The target of the present study was to prepare the microbeads of Simvastatin to provide control release of the drug with enhanced bioavailability through sustained release. The method adopted to prepare Simvastatin loaded microbeads was by the ionic gelation...
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COGNITION ENHANCING ABILITY OF A POPULAR GREEN LEAFY VEGETABLE- CHENOPODIUM ALBUM: IN-VITRO AND IN-VIVO CORROBORATION
Oxidative stress and cholinergic deficit are major culprits of cognitive impairment. Intake of green leafy vegetables - rich in antioxidant phytoconstituents- strongly correlates with memory-preserving capacity. Our earlier work showed that hydromethanol (HM) extract of Chenopodium album (a common leafy vegetable) had strong acetylcholinesterase inhibitory and antioxidant activity in-vitro. The ob...
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EXPLORATION OF ANTI-ATHEROSCLEROTIC ACTIVITY OF ORIGANUM MAJORANA L. IN EXPERIMENTAL ANIMALS WITH HIGH-FAT DIET-INDUCED ATHEROSCLEROSIS
Atherosclerosis is a chronic inflammatory disease that is marked by atheroma and patchy intimal plaques in arteries that cause thickening and hardening of arteries. It is reported that “Origanum majorana L.” possess antiulcerogenic, antiproliferative, antioxidant, and anticarcinogenic activities, and it is an important remedy against thromboembolic disease. The present study was designed for t...
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COMPARATIVE STUDY OF PHYSICO-CHEMICAL AND PHYTOCHEMICAL SCREENING OF SOME SELECTED ANTIDIABETIC MEDICINAL PLANT
The present paper deals with the investigation of comparative physicochemical and phytochemical screening of five medicinal plants viz., leaves of Gymnema sylvestre, fruits of Momordica charantia, rhizomes of Curcum alonga, seeds of Eugenia jambolana and fruits of Embilica officinalis widely used in the treatment of diabetes. In the present communication, comparative results were shown. Various ma...
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FORMULATION DEVELOPMENT OF PVP-BASED SOLID DISPERSION OF LUMEFANTRINE WITH PIPERINE FOR SOLUBILITY ENHANCEMENT
The oral bioavailability of lumefantrine (LUMF) is low and erratic owing to its low aqueous solubility and P-glycoprotein (P-gp) mediated efflux. The present investigation aims to develop amorphous solid dispersions (SD) of LUMF co-loaded with piperine (PIP), a P-gp and CYP3A4 inhibitor, to improve its dissolution and thereby oral bioavailability. LUMF-SDs were prepared by using Polyvinyl-pyrrolid...
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GC-MS ANALYSIS AND IN-SILICO ADMET ANALYSIS OF THE AQUEOUS METHANOL LEAF EXTRACT OF ISODON TERNIFOLIUS (D. DON) KUDO
Medicinal plants contain phytocompounds which are of medicinal value. Scientific evaluation of these compounds that may serve as potential drugs is important in validating the medicinal plants. The leaf extract of the medicinal plant, Isodon ternifolius (D. Don) Kudo was prepared by the maceration method using 80% aqueous methanol as the extraction solvent. The resulting extract was subjected to ...
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EFFECTS OF OPTIMIZATION OF NUTRITIONAL REQUIREMENTS AND INFLUENCE OF ENVIRONMENTAL PARAMETERS ON BIOSURFACTANTS DERIVED FROM MARINE BACTERIA
In the present study, biosurfactant-producing microorganisms such as KM1 (Bacillus licheniformis - Kasemedu 1), KM2 (Bacillus subtilis - Kasemedu 2), ER1 (Pseudomonas aeruginosa - Ennore site 1), ER1B (Pseudomonas mendocina - Ennore site 1) and ER9 (Streptococcus lactis - Ennore site 2) were subjected to optimization studies. The optimization study was carried out using various carbon, nitrogen so...
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DOCKING STUDY OF FLT3 RECEPTOR WITH TYROSINE KINASE FOR LEUKEMIA DISEASE
Leukemia is a disease of cancer that affects blood-forming tissues i.e., bone marrow and lymph nodes, which is associated with uncontrolled growth of WBCs. These cells are unable to fight against infection and weaken the ability of bone marrow to make RBCs and platelets. When leukemic cells overproduce, they interfere in circulatory cells' functioning, i.e., RBCs and platelets. Along this, leukemi...
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PRELIMINARY STUDY OF ANTIMICROBIAL ACTIVITY AND PHENOTYPIC CHARACTER FROM ACTINOMYCETES AND PENICILLIUM SP
Indeed, Actinomycetes and Penicillium are microorganisms that live in different ecosystems. Besides, they play important roles in various fields in respect such as agriculture, medicine and the environment. During this study, we were interested in the isolation of two strains namely: Actinomycetes and Penicillium sp. from coconuts and truffle respectively. In addition, the agar cylinder technique ...
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A REVIEW ON PULSATILE DRUG DELIVERY SYSTEMS
In present days, solid oral drug dosage forms are widely used and the largest part of the entire drug delivery system due to their more, easy preferable route of administration and improved patient convenience nature. Most of the oral drug delivery systems show a distinctive drug release pattern, and the drug concentration is maintained within the limit of the therapeutic range. With technological...
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