Posted by admin on Feb 25, 2015 in |
Cinnarizine was microencapsulated with Eudragit RS100 using an o/o and o/w emulsion solvent evaporation technique. The effects of three formulation variables including the drug: polymer ratio, emulsifier (polyvinyl alcohol) concentration and volume of external medium on the entrapment efficiency and microspheres size distribution were examined. The drug release rate from prepared microspheres and the release kinetics were also studied. The results demonstrated that microspheres with good range of particle size can be prepared, depending on the formulation components. The drug: polymer ratio had a considerable effect on the entrapment efficiency. However, particle size distribution of microspheres was more dependent on the volume polyvinyl alcohol concentration rather than the drug: polymer ratio. The release kinetics was also studied and it was shown that the release profiles of all formulations showed good correlation with the korsmeyer model of...
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Posted by admin on Feb 25, 2015 in |
Depression produces serious emotional and psychological disorders and has severe consequences if not managed at proper time .With the progression of emotional load of depression one is unable to cope up with the extreme negative feelings and tend to create the world of their own thoughts which may end with the end of their life. Whatever forms of symptoms may be related to the grief, depression is far different from normal sadness in that it engulfs our day-to-day life interfering with ability to work, study, eat, sleep, and having fun. World Health Organization W.H.O. (Mental Health and Substance Abuse; Facts & Figures) reported that 15% of depressed persons end their lives in the form of suicide at younger age. Tendency of developing suicidal behavior among the depressed persons is very lethal entangled condition. People who have an impulsive desire to die or perceive suicidal thoughts are very risky. Simultaneously there are many depressed persons who do not have suicidal plan but they prefer to die through some sudden severely...
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Posted by admin on Feb 25, 2015 in |
Fish makes a vital contribution to the survival and health of a significant portion of the world’s population. Upeneus vittatus, a marine species found in the coast of Bay of Bengal, Visakhapatnam was selected for the present study. An attempt is made to know the distribution of Protein, lipids and carbohydrates in muscle and liver of infected and normal Upeneus vittatus. It is observed that a significant difference between infected and normal fish in relation with Lipid content. Lipid levels were observed to be more in the fish with...
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Posted by admin on Feb 25, 2015 in |
The complexes of Ru(III) having general formula [Ru(L)Cl(PPh3)] where L= azo Schiff base derived from 2-aminopyridine, 2-hydroxy naphthaldehyde /vanillin and ethylene diamine have been synthesized. The ligands as well as complexes have been characterized by elemental analysis, molar conductance, magnetic susceptibility, infra-red and electronic spectral data. The azo Schiff base ligand acts as a tetradentate ligand co-ordinating to Ru through azomethine nitrogen and phenolic oxygen atoms. An octahedral geometry has been proposed for the complexes based on electronic spectra and magnetic susceptibility studies. Low molar conductance values revealed the non-electrolytic nature of the complexes. The complexes have been screened for antimicrobial and anticancer...
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Posted by admin on Feb 25, 2015 in |
The plants used for the present study viz., Psidium guajava L and Citrus aurantium belong to the family Myrtaceae and Rutaceae respectively. Guava is native to tropical America. The young leaves are used as tonic in digestive disorders. Bitter orange is native of South Eastern Asia; grow in Tamil Nadu, Karnataka, Maharashtra, Punjab and Uttar Pradesh. It is a rich source of provitamin A. The present investigation on the fluorescent characters of the leaf powder showed varied colours like green, pale green, dark green, brown and yellow under different chemical treatments in both the medicinal plants used for the...
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