Posted by admin on Jan 30, 2015 in |
Objective: The self-medication phenomenon is one of the acute health problems particularly in women and as encountering a sensitive period such as pregnancy is of critical importance. The present study has been conducted to determine the prevalence and causes of this phenomenon in the pregnant women in the city of Ahwaz, located in the west south of Iran. Methods: In this descriptive-analytical study 801 pregnant Women referring to seven health centers in Southern of Iran were selected randomly based on the family (medical) file number and by proportional distribution to each center as a research unit and semi-structured questionnaires were completed through interviews. The data were analyzed by Chi square test and logistic regression. Results: The findingsshowed that 30.6% of etweender the age of 25. self-medicationwomen use self-medication showed 30.6% self-medication in pregnant women. The most frequent group were those under the age of 25. Most frequent self-medication cases belonged to the age group less than 25 years.The most common self-medication cases were digestive disorders. There was a significant relation between...
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Posted by admin on Jan 30, 2015 in |
Lannea kerstingii Engl. & K. Krause stem bark (Anacardiaceae) is used to treat anaemia, malaria, infections and Burili ulcer. The antioxidant, antihelmintic and trypanocidal properties have been demonstrated using appropriate in vitro and in vivo assays. But the effective doses have demonstrated toxic effects such as a significant decrease of body weight of the experimental animals. This work aimed to evaluate the 60 days repeated-dose toxicity of hydroalcoholic extract from Lannea kerstingii stem bark. After 60 days administration, L. kerstingii induced 50% of rats death; accumulation of gas in the digestive tract and a significant decrease of rats body weight. The determination of the toxic mechanism has shown that L. kerstingii decreased the daily food intake and the intestinal motility. The decrease of the intestinal motility by I.P. administration was higher than by P.O. administration. Naloxone, inhibited the effect of L. kerstingii on the intestinal motility. L. kerstingii stem bark hydroalcoholic extract possess a significant inhibition effect on ileum contraction. Therefore it can be toxic in prolonged use at...
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Posted by admin on Jan 30, 2015 in |
The association between chronic bronchitis and cataract is debating. While some referred it to the corticosteroid therapy commonly prescribed to bronchitis, other named different immunological pathways that may be involved in this relationship. We tried to find out the possible immunological benefit of phosphodiesterase IV inhibition in these two common associated conditions. The rats were divided into 4 groups; I: control , II: Selenium (Se), III: roliprampretreated and IV: rolipram post treated groups. Lenses and lung tissues were collected by the end of 2nd week. Upper lobe of right lungs was used to calculate the wet/dry ratios. Histological examinations using H&E, Malloryʼs trichrome, Proliferation cell nuclear antigen (PCNA) and nuclear factor (NF) Kappa B immunohistochemistry study of the lung were done. Scanning electron microscope and H&E studies of lenses were performed. The lung showed significant (P<0.05) elevation of wet/dry ratios with Se administration. There was infiltration by inflammatory cells, congested blood vessels with thickened wall, collagen fibers were increased (P<0.05) with intense NF-Kappa B immuno-reaction. Moreover, there was increase...
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Posted by admin on Jan 30, 2015 in |
The glucosamine-6-phosphate isomerase and Jacob glycoprotein gene expression levels were assessed during E. histolytica excystation from the feces of five patients. Excystation was performed at 0, 24, 48 and 96 h in Robinson medium, and RNA was extracted from the cysts and trophozoites. cDNA was synthesized to amplify the genes using real-time RT-PCR. The results demonstrated differences according to the incubation time and/or conversion of the cystic phase to the trophozoite, where the most important expression in the genes was observed at 96 h excystation. The expression levels of the genes studied positively correlated with the population of trophozoites during...
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Posted by admin on Jan 1, 2015 in |
Two flavonoids were isolated by performing column chromatographic separation of methanol extract of ariel parts of Derris brevipes (Benth) Baker. Structural elucidation of purified compounds was done on the basis of spectral analysis using IR, 1H NMR, 13C NMR 2D NMR spectroscopy and Mass spectrometry. The structures of the flavonoids were elucidated as 2’, 4’-dihydroxy-4-methoxy-3’-prenylchalcone (compound1) and Leutolin-3′-O-xilofuranose (compound...
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