Posted by admin on Oct 1, 2014 in |
Ayurvedic Medicine originated in India more than 2000 years ago and relied heavily on herbal medicine products. Approximately 80% of India’s 1 billion populations use Ayurveda through more than one-half million Ayurvedic practitioners working in 2860 Ayurvedic hospitals and 22100 clinics. Ayurveda’s popularity in Western countries has increased. There are several reports of adverse effects of these herbal preparations due to the presence of high level of heavy metals such as Lead, cadmium, arsenic, and mercury and this problem has become a matter of concern. The present study was done to check the presence of lead, cadmium, arsenic, and mercury in five major ingredients Ajwain (Trachyspermum copticum), Ginger (Zingiber officinale), Neem tree (Azadirachta Indica L.), Peppermint (Mentha piperita), Turmeric (Curcuma longa) are the most essential and regular used materials for preparation of herbal medicines. These ingredients were procured from different location of Delhi, India, and subjected to analysis by Inductively Coupled Plasma-Optical Emission Spectroscopy (ICP-OES) and Atomic Absorption spectrometer-Vapor Generation Assembly (AAS-VGA). Results were compared with the permissible limits...
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Posted by admin on Oct 1, 2014 in |
Present study aimed to evaluate the nociceptive, neuro-muscular coordination, electrophysiological, biochemical, and histological features of diabetic neuropathy in streptozotocin-induced diabetic rats and the protective effects of Coccinia grandis leaf methanolic extract. Coccinia grandis (200 mg/kg per day) was given to diabetic rats for 3 weeks. Metformin (150 mg/kg body weight) was used as standard reference drug. Coccinia grandis showed its protection against allodynia test. NCV was also attenuated by treatment of Coccinia. The significant decrease in AR shows its protection against diabetic complications. Histological alterations induced by diabetes in the sciatic nerve were restored with Coccinia grandis leaf extract treatment. These results suggest that Coccinia grandis has attenuated progression of diabetic neuropathy in STZ-induced diabetic...
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Posted by admin on Oct 1, 2014 in |
Background: Birth preparedness and complication readiness (BP/CR) are interventions designed to address the delays by encouraging pregnant women, their families, and communities to effectively plan for births and prepare for emergencies. Objective: To assess the knowledge and practice towards birth preparedness and complication readiness among women in Mekelle town, 2013. Methods and Materials: A community based cross sectional study was conducted in 2013 on a sample of 220 women. Data were collected using pre-tested and structured questionnaire. The collected data were analyzed by SPSS for windows version 16.0 and result of the study is presented using texts, tables and graphs. Result: Out of 220 total participants, 145 (66%) mention at least one key danger sign during pregnancy and 42 (19%) mention at least two pregnancy danger signs. Sixty eight (44%), 46 (30%), 22 (14.3%), 17 (11%) of the respondents have been practiced or currently practicing in preparing identify birth place and assistance, items needed for safe delivery, transportation plan, and saving money as an element of BP/CR, respectively. Seventy...
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Posted by admin on Oct 1, 2014 in |
Objective: To evaluate the anticonvulsant activity of ethanolic extract (200mg/kg & 400mg/kg) of Psidium guajava (guava leaves) in albino mice. Methods: Albino mice (25-30gms) of either sex were randomly selected and divided into 4 groups of 6 mice each, Group I (control) – Distilled water (vehicle) 1ml, Group II (Standard) – Valproic acid (40mg/kg), Group III – T1, ethanolic extract of Psidium guajava (200mg/kg), Group IV- T2, ethanolic extract of Psidium guajava (400mg/kg). All drugs were administered orally 1 h before the induction of seizures. The anticonvulsant activity was screened using maximal electroshock (MES) and pentylenetetrazole (PTZ) models. Results: The data were analyzed by one way ANOVA followed by Bonferroni’s multiple comparison test. Ethanolic extract of Psidium guajava dose-dependently produces significant antiepileptic activity in comparison to control. In MES test, the percentage inhibition of seizure is T2 – 49% and T1 – 37% in comparison to control. In the PTZ test, the percentage of protection from seizure by T2 is 83.4%, and T1 is 50% when compared to the...
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Posted by admin on Oct 1, 2014 in |
Impatiens balsamina belonging to family Balsaminaceae is commonly known as terda. The plant has an extensive range of phyto-constituents like naphthoquinones, coumarins, glycosides, phenolic acids, flavonoids, anthocyanidins and steroids which have effective antimicrobial, anti-anaphylaxis, anti-allergic, antipruritic, and anti-inflammatory activity. Potent naphthoquinones like lawsone, methylene-3, 3’-bilawsone and lawsone methyl ether are present in the leaves of the plant that exhibits was proved to possess an intensive antitumor activity. Taking into account these ethnobotanical, nutritional, medicinal and commercial values of I. balsamina, a simple, rapid and sensitive High-Performance Liquid Chromatography method for quantification of three naphthoquinones in is developed. Jasco CrestPak C8 (4.6×250mm, 5μm) RP-HPLC column was used as the stationary phase. Sodium acetate (pH3.2): ACN (50:50% v/v) was used as mobile phase with flow rate 1ml/min and detection at a wavelength of 280nm using PDA multi-wavelength Detector. The developed method was validated for linearity, accuracy, precision, and system suitability. LOD for naphthoquinones was found to be 200ng/mL, whereas LOQ for the same was found to be 600ng/mL. The method was...
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