Posted by admin on Jan 1, 2014 in |
The main objective of the present investigation is to evaluate theantilithiatic activity of ethanolic extract of Tamarindus indica L. on mice. Antilithiatic activity of the ethanolic extract of the Tamarindus indica leaves at a dose of 250mg/kg, 400mg/kg & 500mg/kg was evaluated against the standard drug Cystone was given orally 750mg/kg. Adult Wister Albino rats of either sex of divided in six groups of six animals each as undertaken for study and evaluated by Rat models of calcium oxalate urolithiasis induced by either ethylene glycol (EG) are most commonly used to study the pathogenesis of urolithiasis. Ethanolic extract of Tamarindus indica (at 250, 400 and 500 mg/kg) exhibited a dose dependent significant anti-lithiatic activity on treatment. The extract dose of 250 mg/kg also caused partial reduction of Uria, Uric acid, calcium, Potassium, oxalates, phosphorus and creatinine in blood serum level the results were found statistically insignificant. The antilithiatic effect of ethanol extract at was found less effective than the reference...
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Posted by admin on Jan 1, 2014 in |
The aim of the present study was to investigate the oil composition extracted from Sesamum indicum seeds. The oil was extracted from seeds by soxhlet method and analyzed by gas chromatography-mass spectrometry (GC-MS). A total of 84 different components were identified and out of which 12 are fatty acid components. The principal compounds identified and present in all samples were silane, trimethyl[5-methyl-2-(1-me thylethyl)phenoxy]-; silicic acid, diethyl bis (trimethylsilyl)ester; stearic acid; oleic acid; n-Hexadecanoic acid; myristic acid; indole-2-one 2,3-dihydro-N-hydroxy-4-methoxy-3,3-dimethyl-; cyclotrisiloxane, hexamethyl-; acetamide, N-[-4-(trimethylsilyl)phenyl]-; benzene, 2-[(tert-butyldimethylsilyl)oxy]-1-isopropyl-4-methyl-; benzo[h]quinoline, 2,4-dimethyl-, trichloroacetic acid undec-2-enyl ester and 2-Ethylacridine. Among fatty acids, palmitic acid and oleic acid were identified in highest concentration. In comparison, myristic acid and stearic acid were present in lesser amount. Variation was found between chemical compositions of different genotypes of sesame. The obtained results supported the use of seed oil as edible oil and in pharmaceuticals. This study is also important as identification of volatile compounds in Indian genotypes of Sesamum indicum was done for the first...
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Posted by admin on Jan 1, 2014 in |
The present paper deals with preliminary phyto-chemical screening of Terminalia species (Combretaceae), used by the local tribal communities for different human and veterinary ailments. The personal interviews conducted with local herbal practitioners and review of literature yielded 5 species of Terminalia as an effective remedy for diabetes, dysentery, diarrhoea, asthma, rheumatic pains etc. The fruits of Terminalia species used for maximum number of human and veterinary ailments than leaf and stem bark. Ethyl acetate, methanol and water extracts of fruits was conducted for preliminary phytochemical screening which were used as drug for different ailments and composition of various groups of constituents was...
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Posted by admin on Jan 1, 2014 in |
The present study reports analgesic potential of hydrogels of silver nanoparticles using Saraca indica bark extract makes a fast and convenient method for the synthesis of silver nanoparticles with the aid of microwave. The synthesized nanoparticles were characterized using UV-visible (UV-vis) spectrophotometer, Transmission electron microscopy (TEM), X-ray diffraction (XRD) and Fourier transform infra-red (FTIR) spectrometry. The nanoparticles were found to be spherical in shape and of 5 to 50 nm in size. The hydrogels of synthesized silver nanoparticles exhibited good analgesic activity. Testing was performed on the portion of the tail treated with hydrogels (control, aqueous extract of Saraca indica bark & silver nanoparticle using Saraca indica bark extract) and they were assessed using a fixed quantity of each drug. The tails were subjected to radiant heat two minutes after topical application since the analgesic actions of agents administered in this manner are restricted to the exposed part of the tail. Analgesic activity was checked by digital analgesiometer. Significant analgesic activity was observed with silver nanoparticles using Saraca indica...
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Posted by admin on Jan 1, 2014 in |
The concept of Health-related quality of life takes into account about patient well-being as expressed by both physical and psychological domains of health. The relevance of this concept in end stage renal disease patients has been well established and can be used for routine treatment of patients with renal failure. It is of deemed interest to compare health and wellness of end stage renal disease adult patients undergoing Haemodialysis and Continuous ambulatory peritoneal dialysis in selected hospitals of Malaysia and to study the relationship between disease symptoms experienced by patients with their quality of life. The study was conducted in two government hospitals of Malaysia. The study involved 220 renal impairment patients and their recruitment is based on standard inclusion criteria. Medical outcome study 36-item short form was used to evaluate Health-related quality of life. The symptoms were tested as per the standard revised illness perception questionnaire. Statistical analysis of the completed study shows that there are significant differences in quality of life among patients with variable age groups...
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