Posted by admin on May 1, 2013 in |
Introduction: Mother to Child Transmission of HIV can occur during pregnancy, delivery, and breastfeeding and it accounts for more than 90% of pediatric AIDS. Various studies indicate that the rate of Mother to Child Transmission of HIV is high among infants who were on mixed feeding. UNICEF UNAIDS and WHO recommended that, all women have the right to choose exclusive breastfeeding or exclusive replacement feeding. However, numerous contextual factors can influence mothers in their choices and decisions related to what and how they feed their infants. An understanding of factors that influence women’s adherence to the recommended infant feeding is critical in identifying ductile point’s intervention. Objective: The study aims to explore the experiences of infant feeding practices of HIV positive women who have used Prevention of Mother to Child Transmission service. Method: Qualitative data were collected by the principal investigator using semi structured in-depth interview from 12 HIV Positive mothers who use PMTCT service at the Tikur Anbassa hospital and was analyzed using principles of thematic content analysis....
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Posted by admin on May 1, 2013 in |
Recent findings from culture-dependent and culture independent methods have demonstrated that indigenous marine actinomycetes exist in the oceans and are widely distributed in different marine ecosystems. There is tremendous diversity and novelty among the marine actinomycetes present in marine environments. Progress has been made to isolate novel actinomycetes from samples collected at different marine environments and habitats. These marine actinomycetes produce different types of new secondary metabolites. Many of these metabolites possess biological activities and have the potential to be developed as therapeutic agents. Marine actinomycetes are a prolific but underexploited source for the discovery of novel secondary...
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Posted by admin on May 1, 2013 in |
The ethanolic extract of barks of Caesalpinia pulcherrima (Family- Caesalpiniaceae) was evaluated for anti-diarrhoeal and analgesic activities in animal models. The crude ethanolic extract of Caesalpinia pulcherrima showed considerable anti-diarrhoeal activity on castor oil induced diarrhoea in mice and it increased mean latent period and decreased the frequency of defecation significantly (P<0.001) at the oral dose of 500 mg/kg body weight comparable to the standard drug Loperamide at the dose of 50 mg/kg of body weight. The extract of barks also produced significant (P<0.001) writhing inhibition in acetic acid induced writhing in mice at the oral dose of 500 mg/kg body weight where writhing inhibition for the extract of barks was 47.11%, which was comparable to the standard drug Diclofenac sodium at the dose of 25 mg/kg of body...
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Posted by admin on May 1, 2013 in |
Antibiotic resistance in pathogens is on the increase but in the past few decades this problem raised a deepening concern among scientific community in terms of the clinical management of infectious diseases. In this review, the common gram negative clinically significant pathogenic bacteria who have acquired resistance with passage of time like Shigella dysenteriae, Sh. Boydii, Sh. Flexneri, Listeria monocytogenes, Acinetobacter baumannii, acinetobacter, A. baumannii, Morganella morganii, Enterobacteriaceae, Citrobacter freundii, Citrobacter braakii, or Citrobacter amalonaticus, P. stuartii, Providencia rettgeri, P. alcalifaciens, P. rustigianii, E. coli, Salmonella. paratyphi, S. typhi, Salmonella enterica, have been compiled with their plausible ways of causing resistance. We conclude from our literature review that resistance in gram negative bacteria is on the rise and new and advanced antibiotics need to be designed and...
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Posted by admin on May 1, 2013 in |
Aim: To investigate the possible association of OCT1 rs122083571 polymorphism (C/T allele) with glycemic status and serum metformin levels in type II Diabetes mellitus. Methods: Sixty already diagnosed T2DM patients on metformin monotherapy (500 mg, bd) were recruited for the study and the genotypes for SLC22A1 rs122083571 C/T polymorphism using PCR assay were done. Serum fasting plasma glucose (FPG), Postprandial Plasma Glucose (PPG), Glycated Hemoglobin (HbA1c), Fasting Serum Insulin (FINS), Triacylglycerol (TG), Cholesterol (CHO), Low-Density Lipoprotein (LDL-c), High-Density Lipoprotein Cholesterol (HDL-c), and Homeostasis Model Assessment for Insulin Resistance (HOMA-IR), Body Mass Index (BMI), blood pressure (BP) were determined. Results: In patients with C allele, the BMI,BP ,FPG ,PPG and Insulin levels were significantly higher when compared to that of the T allele subjects .The values of TGL and HDL in both groups of T2DM patients were not significantly different. But the total cholesterol level and LDL level were significantly increased in T2DM patients with C allele. Conclusion: SLC22A1 rs122083571 C allele is associated with poor glycemic status in spite...
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