Posted by admin on Jul 1, 2013 in |
The selected amide and ester derivatives of ferulic acid were subjected to preservative efficacy testing in an official antacid preparation, (Aluminium Hydroxide Gel-USP) against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Candida albicans and Aspergillus niger as representative challenging microorganisms as per USP 2004 guidelines. The selected derivatives were found to be effective against all selected strains and showed preservative efficacy comparable to that of standard and even better in case B. subtilis and C. albicans. The 8- hydroxy quinoline ester derivative showed better preservative efficacy than standard as well as other derivatives and have better potential for use in the pharmaceutical...
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Posted by admin on Jul 1, 2013 in |
A series of some New 2, 3-dihydro-1, 5-benzodiazepines has been synthesized using condensation reaction of o-phenylenediamine and various substituted chalcones in presence of DMF as solvent and screening of antibacterial and antifungal activities of synthesized...
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Posted by admin on Jul 1, 2013 in |
Catharanthus roseus is a medicinal herb found in many tropical and subtropical regions around the world. This plant produces a diverse array of secondary metabolites that are pharmaceutically important like vinblastine and vincristine used as chemotherapeutic agents in the treatment of several types of cancers. Low yield of these vinca alkaloids from the plant in vivo and the challenges to meet their high demand worldwide led researchers to develop various in vitro techniques like hairy root culture, callus cultures, shoot cultures, metabolic engineering and regulation studies to increase their production. The present review gives an account of the various phytochemicals derived from the plant and the pharmacological aspects of secondary metabolites studied. Present review also highlights the biotechnological prospects of an efficient and alternative means of production of valuable metabolites from Catharanthus roseus and also from rich microflora residing inside the plant tissues. It gives an emphasis on the need of exploration of diverse niches of...
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Posted by admin on Jul 1, 2013 in |
The focus of this exploratory study was to investigate pharmacy academics’ perception of their role in the Libyan health. A cross sectional survey design was used in this study. Using a questionnaire developed following an extensive literature review, a survey cross was undertaken in Libya from June to September 2010. The respondents’ were pharmacy academics who had graduated from pharmacy faculties and were teaching at Libyan pharmacy faculties naming universities (Alfateh Tripoli and Alarab Medical Benghazi). The majority of respondents’ reported that they did not teach courses related to social pharmacyin their institutions.There was substantial willingness among academics to incorporate social pharmacy subjects to pharmacy curriculum in Libya. The results obtained from the present study revealed that social pharmacy subjects are not fully thought and given priority in the Libyan pharmacy...
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Posted by admin on Jul 1, 2013 in |
Polychlorinated dibenzo-p-dioxins(PCDDs) and Polychlorinated dibenzofurans(PCDFs) represent a large group of industrial and byproduct compound is resistance to chemical and biological degradation and highly toxic.A series of 18 PCDD and PCDF compounds is subjected to QSTR studies by using differnt molecular descripters. The dependent variable used in this study represents log(EC50) values (EC50-median effective concentration during a bioassay).The regression analysis of the data has shown that the toxicity of the compound can be modeled excellently in multi-parametric model.Its resulting model exhibited good R2value up to 0.8938. The present work contribute in the identification of those compounds which are very toxic and polluting our...
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