Posted by admin on Jun 1, 2012 in |
Parkinsonia acculeata is used in traditional medicine for the treatment of jaundice and diabetes. Accordingly, the present study was designed to investigate the effects of Pet ether and aqueous extracts of the leaves of Parkinsonia acculeata on glucose homeostasis in alloxan induced diabetis in rabbits. After 7 days of study it showed that Parkinsonia acculeata reduced glucose levels significantly. The extracts were also able to reduce quantatively C reactive proteins and levels of SGOT and SGPT enzymes. It was concluded that due to its potent antioxidant and antidiabetic properties, the Parkinsonia acculeata extract exerts remarkable antidiabetogenic...
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Posted by admin on Jun 1, 2012 in |
The prophylactic efficacy of garlic (Allium sativum Linn.) (Alliaceae) extract was studied on changes in WBC differential count pattern in male albino rats. The rats were divided into four groups A, B, C and D, keeping group A as a healthy control. The garlic extract was tried in three different doses, 1ml, 2ml and 4ml/ kg body weight as low, medium and high dose respectively and given orally for the period of 7, 14, 21 or 28 days daily to the rats of group B, C and D as stated above. The results clearly indicate that a significant increase (P<0.01) in lymphocyte and eosinophil percent and a significant decrease (P<0.01) in neutrophil and monocyte percent at low and medium dose but at higher dose their percentage increases within the normal values. This investigation indicates not only the benefits and drawback of raw garlic but also its uses in regulation of certain parameters for well-being of...
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Posted by admin on Jun 1, 2012 in |
Direct compression is the preferred method for the preparation of tablets. Co-processing is the one of the most widely explored and commercially utilized method for the preparation of directly compressible vehicles. The objective of the present study is to prepare and characterize pregelatinized starch-poly vinyl pyrrolidone (PGS-PVP) co-processed excipient and to evaluate its application as directly compressible vehicle in tablet formulations. PGS-PVP co-processed excipient was prepared by gelatinizing potato starch in the presence of PVP and drying the resulting mass. The co-processed excipient prepared was characterized by determining melting point, solubility, swelling index in water, pH, and micromeritic characters namely particle size, bulk density, tapped density, angle of repose and compressibility index, by FTIR spectra and evaluated for its application in tablet formulations. PGS-PVP co-processed excipient prepared by gelatinizing potato starch (49 parts) in the presence of PVP (1 part) is a crystalline, discrete and free flowing powder. It is insoluble in water and aqueous fluids of pH 1.2, 4.5 and 7.4 and in several organic solvents. It exhibited...
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Posted by admin on Jun 1, 2012 in |
The ethanolic extract of leaves of Acalypha hispida was evaluated for phytochemical, cytotoxic and antibacterial activities. Phytochemical studies revealed the presence of flavonoids, saponins, glycosides, reducing sugars and steroids. Cytotoxic activity was investigated by brine shrimp (Artemia salina) lethality assay. The extract showed potent cytotoxic effect (LC50 19.95µg/ml) which is comparable to standard cytotoxic drug chloramphenicol (LC50 7µg/ml). Antibacterial activity was tested by disk diffusion method. The extract exhibited significant antibacterial activity against Salmonella typhe and moderate activity against Enterococcus coli, Streptococcus saprophyticus and Streptococcus agalactin whereas Shigella dysentery found resistant at 250µg/disc and...
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Posted by admin on Jun 1, 2012 in |
Bionanotechnology has emerged up as integration between biotechnology and nanotechnology for developing biosynthetic and environmental friendly technology for synthesis of nano materials. Silver has been known to have effective bactericidal properties for centuries. Nowadays, silver based topical dressings have been widely used as a treatment for infection in burns, open wounds, and chronic ulcer. As the pathogenic organisms are getting evolved day by day due to mutation and gaining antibiotic resistance, an important industrial sector of nanosciene deals with the preparation and study of nanoparticles in antibacterial clothings, burn ointments and coating for medical device. The size of nanomaterials is much smaller than that of most biological molecules and structures, therefore nanomaterials can be useful in both in vivo and in vitro biomedical research application. The purpose of the study is to synthesis and characterizes the fungal silver nanoparticles using F.oxysporum. Further investigation of the shape and size of fungal nanoparticle was done by X-ray diffraction and Scanning electron microscopic studies. A silver nanoparticle at different concentration was assessed...
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