Posted by admin on May 1, 2011 in |
Objective: To assess and educate about home medicine cabinet among randomly selected houses of people in community of Greater Noida city & to carry out the survey of medicines proper storage, safe use, list of total and expired drugs, their disposal and maintenance of home medicine cabinets. Method: This study was a simple randomised prospective survey study. This prospective study was carried out for a period of six months in selected areas of Greater Noida City. The study site was the homes sited in those areas by simple randomization. Key findings: Randomly selected 102 houses were visited to educate and assess the people about Home Medicine Cabinet. A total of 392 people were surveyed in 92 houses with exception of 10 houses. During the period of the study, most of the expired drugs are in the category of analgesics and NSAID’s (23.93%) followed by nutritional supplements (22.56%), antibiotics (14.94%), expectorants and mucolytics (6.77%), bronchodilators (5.31%) and antacids (6.53%),Number of House members involved in self medication decreased from 72 houses...
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Posted by admin on May 1, 2011 in |
The present study deals with the Pharmacognostical and preliminary phytochemical studies of fruit pulp of Aegle marmelos. Macroscopy, organoleptic characters, microscopic features, physiochemical standardization parameters such as total ash, acid insoluble ash, water soluble ash, alcohol, water and other organic solvent extractives, preliminary phytochemical assay, fluorescence analysis and microbial limit assay were performed using standard textual methods. The Pharmacognostical results showed the following observations that are total ash (3.8%), acid insoluble ash (2.05%), water soluble ash (2.9%), water extractives (12%), alcoholic extractives (10.4%), foaming index (333.3U), and swelling index (3.3%). Fruit pulp reveals the presence of steroids, terpenoids, flavonoids, Saponins, phenolic compounds, lignin, fat and oil, proteins, carbohydrates, amino acids and reducing sugars. These observations would be of immense value in the botanical identification and standardization of drugs in a crude...
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Posted by admin on May 1, 2011 in |
Salbutamol (SAL) and Ambroxol (AMB) is used for the treatment of asthma and bronchitis. Two simple, economical, accurate, and precise methods for simultaneous estimation of Salbutamol Sulphate (SAL) and Ambroxol Hydrochloride (AMB) in tablet dosage form have been developed. The methods are absorbance correction method (I) and first order derivative method (II). In first method ambroxol hydrochloride (AMB) was determined directly from calibration plot by measuring absorbance at 300nm and salbutamol sulphate (SAL) was determined after correction for absorbance of ambroxol hydrochloride (AMB) at 223 nm. Second method is based on first order derivative spectroscopy to overcome the spectral interference from the other drug. Wavelength 252 nm was selected for SAL and 232 nm for AMB. Both the methods showed linearity in the concentration range of 2-10µg/ml for SAL and 2-20 µg/ml for AMB. The accuracy and precision of the methods were determined and the methods validated stastically. No significant difference was observed between the results obtained by the two...
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Posted by admin on Apr 1, 2011 in |
A number of aldehydes were reacted with acetyl acetone or ethyl acetoacetate and urea under Biginelli reaction conditions to give the corresponding 5-acyl-4-(substituted-aryl)-6-methyl-3,4-dihydropyrimidin-2-one. The 5-acetyl-derivatives were converted into pyrimido-oxazoles, pyrimido-pyrazoles, and chalcones. Some Mannich bases were also synthesized. Some selected compounds were tested for their antimicrobial...
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Posted by admin on Apr 1, 2011 in |
The plant of Baliospermum montanum (Willd.) was shaded dried, and then these were made into coarsely powdered by using dry grinder. The powdered roots of the plant (200gm) was packed in soxhlet apparatus and continuously extracted with petroleum ether (40-600C) till complete extraction. After completion of extraction, the solvent was removed by distillation and then concentrated extract obtained was dried under reduced pressure using rotatory evaporator at temperature not exceeding 400C and then moderate heating on water bath. A dark brown extract approximate 2 gm. was obtained. From the drug petroleum ether was removed and the defatted drug was extracted with ethanol (95%) till complete extraction, after completion of extraction the solvent was removed by distillation and then concentrated extract obtained dried under reduced pressure at temperature not exceeding 400C and then give moderate heating on water bath. The ethanol extract obtained was dark brown in color weighed about 18gm. The ethanolic extract was kept in petri dish and it was stored in desiccators at cool...
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