Posted by admin on Jun 1, 2011 in |
Some N-{4-[(6-chloro-4-oxo-4H-chromen-3-ylmethylene) imino] phenyl}-2-(substituted phenoxy) acetamide derivatives (3) were synthesized by reacting N-{4-[(6-chloro-4-oxo-4H-chromen-3-ylmethylene) imino] phenyl}-2-chloroacetamide (2) with some substituted phenol in dry acetone in the presence of K2CO3 and catalytic amount of KI. The chemical structures of the compounds were elucidated by IR, 1H-NMR and elemental analysis. Their antibacterial activity against gram positive bacterial strains (S. aureus and B. subtilis) and gram negative bacterial strains (E. coli and P. aeruginosa) were investigated by disc diffusion method. The antifungal activity of these compounds was also tested against A. niger and A. flavipes. The results showed that some of the compounds have strong antimicrobial...
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Posted by admin on Jun 1, 2011 in |
Nutritional deficiency is almost impossible to avoid in these modern times, thus natural supplements help us to overcome the nutritional deficiencies. It also helps us to boost our immune system. Nutritional supplements are also useful in getting rid of the toxins that are accumulated in our body. Thus, the five natural supplements that are mentioned below are tested for the various parameters that include the basic Quality Control Parameters, the phyto chemical analysis, Microbial Analysis that includes the testing for the presence of pathogens along with the total bacterial and fungal count. It is also tested for the presence of heavy metals in them, followed by Aflatoxin and Pesticide analysis. The Nutritional Value for each of them were determined and calculated. The actives of Garcinia Capsule, Ginger Capsule and Holy Basil Capsule were confirmed by the HPLC...
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Posted by admin on Jun 1, 2011 in |
A series of 1, 3, 4-thiadiazole derivatives were synthesized. The structures of these compounds were established by means of IR, 1H-NMR and mass spectrum analysis. All the compounds were evaluated for antibacterial and antifungal activities. Most of the compounds have shown significant antibacterial and antifungal activity when compared with the standard...
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Posted by admin on Jun 1, 2011 in |
Aim of study is to evaluate the potential anti-tussive activity in a mouse model induced by sulphur dioxide gas of ethanolic extract of “Rosa centifolia”. The ethanol extract of Rosa centifolia (250mg/kg 500 mg/g p.o) showed significant anti-tussive activity, the cough inhibition (35% and 57% respectively) and being comparable to that of 10-20mg/kg of codeine phosphate (41 and 64% respectively).The effect of ethanolic extract on the trachea was also tested it did not relax pre-contractions in guinea pig trachealis induced by KCl and...
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Posted by admin on Jun 1, 2011 in |
The present investigation was undertaken to study the antimicrobial and antioxidant activity in algae (Chlamydomonas reinhardtii CC 124). The extractions of metabolites were done by two methods (glass bead and steel ball) using methanol: chloroform: water (5:2:2) as solvents. The presences of metabolites were identified by thin layer chromatography and structural analysis was done by Gas Chromatography and Mass Spectrometry. Antimicrobial activities of the extracts were assessed against bacterial and fungal strains (Bacillus subtilis, Pseudomonas aeruginosa, Klebsiella pneumoniae, Candida albicans, Aspergillus niger, Aspergillus flavus) by disc diffusion method and compared with standard antibiotics. The results, of both extracts showed more potent antimicrobial activity in (B. subtilis,P. aeruginosa, K. pneumoniae) bacterial species and (C. albicans) fungal strain. The antioxidant activity was tested by DPPH (2, 2-Diphenyl-1-picrylhydrasyl) free radical method and determination of H2O2 radical scavenging activities were also performed. The presence of antioxidants was compared with commercial antioxidants, such as BHT (Butylated Hydroxy Toluene), BHA (Butylated Hydroxyl Anisole).The phenolic content was compared with gallic acid. From the present study, it...
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