Posted by admin on May 1, 2011 in |
Based on the scope given by traditional knowledge, present study was conducted. The aim of the present study was to evaluate the antibacterial activity of castor (Ricinus communis, Family: Euphorbiaceae) leaf extract using five bacteria; two Gram-positive bacteria (Bacillus subtilis and Staphylococcus aureus) and three Gram-negative bacteria (Escherichia coli, Proteus vulgaris, Pseudomonas aeruginosa). The concentrated ethanolic extract of the crude drug of concentration 5gm/ml was tested for antibacterial activity by determination of zone of inhibition. Gentamycin is used as standard. It was found that the concentrated extract of the Ricinus communis leaves showed a better antibacterial activity in comparison with the...
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Posted by admin on May 1, 2011 in |
The proposed method is new, simple, sensitive, reproducible, economical, accurate and precise and can be successfully applied in estimation of Telmisartan (Telmi) from urine. This method can find applications in clinical studies and therapeutic drug monitoring. This method of colorimetric estimation of telmisartan from urine is based on the formation of yellow colored chromogen when it is reacted with alizarin in presence of thionyl chloride. The concentration of telmisartan over a range of 10-60 µg/ml was found to obey Beer’s law in the stated range. The yellow colored complex has absorption maxima at 427 nm with molar absorptivity and sandell’s sensitivity 2.2387 × 104 lit mol-1cm-1 and 0.0154 µg/cm2/0.001 absorbance units, respectively. The proposed method is highly sensitive, reproducible, specific, and the reagent was not found to react with the soluble matters of the body fluids. The results of analysis were validated as per ICH Q2B guidelines....
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Posted by admin on May 1, 2011 in |
To study the anti-inflammatory effect of different extract of leaves of Diplazium esculentum in rats. Anti-inflammatory activity was screened by measuring the reduction in carrageenan induced hind paw edema. The potency of various extracts of leaves was compared with each other and standard Ibuprofen (100mg/kg) for anti-inflammatory activity. The results indicated that all the extracts of Diplazium esculentum showed anti-inflammatory activity. Percentage inhibition of inflammation observed in chloroform extract group was more than other treated...
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Posted by admin on May 1, 2011 in |
Biodiesel is produced from vegetable oils (edible & non edibles) and animal fats. The methyl ester of vegetable oils, known as biodiesel are becoming increasingly popular because of their low environmental impact and potential as a green alternative fuel for diesel engine and they would not require significant modification of existing engine hardware. At present, biodiesel is commercially produced from the refined edible vegetable oils such as Schlichera oleosa seeds oil, etc. by alkaline-catalyzed esterification process. This process is not suitable for production of biodiesel from many unrefined non-edible vegetable oils because of their high free acid value. Hence, a two-step esterification method is developed to produce biodiesel from high FFA vegetable oils. The biodiesel production method consists of acid-catalyzed (H2SO4) pretreatment followed by an alkaline-catalyzed (KOH) transesterification. Methyl ester of Schlichera oliosa is derived through esterification and transesterification...
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Posted by admin on May 1, 2011 in |
Objective: To assess and educate about home medicine cabinet among randomly selected houses of people in community of Greater Noida city & to carry out the survey of medicines proper storage, safe use, list of total and expired drugs, their disposal and maintenance of home medicine cabinets. Method: This study was a simple randomised prospective survey study. This prospective study was carried out for a period of six months in selected areas of Greater Noida City. The study site was the homes sited in those areas by simple randomization. Key findings: Randomly selected 102 houses were visited to educate and assess the people about Home Medicine Cabinet. A total of 392 people were surveyed in 92 houses with exception of 10 houses. During the period of the study, most of the expired drugs are in the category of analgesics and NSAID’s (23.93%) followed by nutritional supplements (22.56%), antibiotics (14.94%), expectorants and mucolytics (6.77%), bronchodilators (5.31%) and antacids (6.53%),Number of House members involved in self medication decreased from 72 houses...
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