Posted by admin on Nov 1, 2010 in |
The ethanol extract of Wattakaka volubilis (L. f) Stapf. (Family: Asclepiadaceae) leaf was investigated for its antidiabetic effect in Wistar Albino rats. Diabetes was induced in Albino rats by administration of alloxan monohydrate (150mg/kg, i.p). The ethanol extract of Wattakaka volubilis at a dose of 150mg/kg of body weight was administered at single dose per day to diabetes induced rats for a period of 14 days. The effect of ethanol extract of Wattakaka volubilis leaf extract on blood glucose, plasma insulin, glycosylated haemoglobin, serum lipid profile [total cholesterol, triglycerides, low density lipoprotein – cholesterol (LDL-C), very low density lipoprotein – cholesterol (VLDL-C), and high density lipoprotein- cholesterol (HDL-C) serum protein, albumin, globulin, A/G ratio, serum enzymes [Serum glutamate pyruvate transaminases (SGPT), serum glutamate oxaloacetate transaminases (SGOT) and alkaline phosphatase (ALP)], lipoprotein peroxidation (LPO) antioxidant enzymes (catalase (CAT), superoxide dismutase (SOD), reduced glutathione (GSH) ,glutathione peroxidase (GPx) and glutathione reductase (GR) were measured in the diabetic rats. The ethanol extract of Wattakaka volubilis leaf elicited significant reductions of blood glucose...
Read More
Posted by admin on Nov 1, 2010 in |
Aim: The aim of the study was to determine the outcomes and complication of preeclampsia syndrome in pregnancies Methodology: It was a Prospective observational study conducted at Indira Gandhi memorial hospital, Shirpur, Dhule. In this study a total 971 primigravida and multigravida pregnant women was observed out of which, 73 preeclamptic pregnancies were reviewed from July 2009 to February 2010. All study related data collections were conducted in accordance with Ethical background for Investigations of the preeclampsia syndrome. Results: A total 73 preeclamptic pregnancy (7.51%) syndrome was observed in between 18-22 (61.64%) years of age and in primigravida (n=43) and most of pregnant women found to be the middle class. The data of pathological report, month of pregnancy and neonatal outcomes differences was statistically significant. The preeclampsia surveillance mainly diagnosed at mild hypertension (n=64) 140/90 mmHg, severe hypertension (n=9), proteinuria found to be trace amount to ≥ 1+ dipstick and face, leg, and palm edema were observed. Also, HELLP syndrome was (8%), in which hemolysis7.40±0.54 gm%, low platelet count...
Read More
Posted by admin on Nov 1, 2010 in |
Comparative Pharmacognostical studies of Anisomeles Linn. R. Br. species (Lamiaceae) in India are carried out. These species are Anisomeles indica L. Kuntze (Syn. A. Ovata R. Br.) and Anisomeles malabarica L. R. Br. Ex Sims, which are highly found in throughout south (Deccan plateau) and northeastern India. The study conducted with the aim of drawing the Pharmacognostical standards for differentiate the species. Macroscopical and microscopical characters, physio-chemical constants, quantitative microscopy parameters, extractive values, fluorescence analysis of extracts, its reaction after treatment with chemical reagents under visible light and UV light carried out. Preliminary phytochemical screening and TLC fingerprint on the various extracts from aerial part of Anisomeles species was also studied. According to the anatomical comparison between two species, the pith structure, sclerenchyma ring of the stems, the cuticle thickness of the leaves, and stomatal distribution on the leaves are the distinguishing features of the species. The determination of these characters will help future researchers in their Phytochemical as well as Pharmacological analysis of this...
Read More
Posted by admin on Nov 1, 2010 in |
The present study was aimed at evaluating the antidiabetic activity of aqueous extract of fruits of Artocarpus heterophyllus (Moraceae) in alloxan induced type- II diabetes in rats. The diabetic rats were administered aqueous fruit extract (250 and 500 mg/kg, p.o., n = 6) or vehicle (gum acacia solution) or standard drug glibenclamide (0.25 mg/kg) for 15 days. Blood samples were collected by retro-orbital puncture and were analyzed for serum glucose on 0, 5, 10 and 15th day by using glucose oxidase-peroxidase reactive strips and a glucometer. In oral glucose tolerance test, glucose (2gm/kg, p.o.) was administered to nondiabetic control, glibenclamide (10 mg/kg, p.o.) and extract treated rats. The serum glucose levels were analyzed at 0, 30, 60 and 120 min after drug administration. The effect of the extract on body weight of the diabetic rats was also observed. The serum insulin level and lipid profile were estimated. The extract showed significant reduction (p<0.05) of fasting blood glucose level in alloxan induced type- II diabetic rats on 10th and 15th...
Read More
Posted by admin on Nov 1, 2010 in |
The aim of this study was to evaluate antimicrobial activity of the leaves of the Bauhinia racemosa L. In the current study, the aqueous and methanol extract of leaves of B. racemosa L. was tested against standard bacterial and fungal cultures. In vitro antimicrobial test was performed by agar well diffusion method on Mueller hinton agar and Sabouraud dextrose agar for bacterial and fungal cultures respectively. Minimum inhibitory concentration test was performed by modified agar well diffusion method. Methanol extract showed significantly higher inhibitory effect compared to aqueous extract on tested organisms. The methanol extract showed a broad spectrum of antimicrobial activity as it inhibited Gram negative bacteria (Escherichia coli, Micrococcus luteus, and Pseudomonas aeruginosa), Gram positive bacteria (Bacillus subtilis) and fungi (Candida albicans and Aspergillus niger). Both extracts showed maximum relative percentage inhibition against A. niger. MIC values for methanol extract varied from 1.5-25 mg/ml. Phytochemical analysis of crude methanol and aqueous extract suggested the presence of protein, oil and fats, phenolic compounds, flavonoids, saponins tannins and carbohydrates...
Read More
