Posted by admin on Jun 30, 2020 in |
Aegle marmelos L. (Bael), is a commonly occurring herb which has biomedical potency to treat many types of diseases such as diarrhea, hepatoprotective, epilepsy, stomachalgia, digestion related problems etc. The different parts of Aegle marmelos (L.) were collected, dried and coarsely powdered. The present study deals with the physio-chemical constants standardization parameters such as pH, solubility including water and methanolic extraction, total ash, acid insoluble ash, water soluble ash, extractive values, dry and wet particle size, foaming index, swelling index, foreign matters, loss of drying (LOD) and acidity were observed. Fluorescence analysis was performed for study of behavioral characters of the pulp without seed, pericarp, leaf and seed powder treated with chemical reagents. Extractive values of powder with solvents such as water and methanol were determined. Macroscopical characters help in identifying the fruit, pulp, pericarp, leaf and seed. Anatomical observations showed the presence of palisade cell, trichomes, mesophyll cell, collenchymas, xylem, phloem, pith, upper epidermal cells and lower epidermal cells with stomata. Preliminary qualitative phytochemical screening reported the presence...
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Posted by admin on Jun 30, 2020 in |
In the present study two subclasses of coumarin derivatives were selected 14 coumarin sulphonamides and 14 coumarin schiff bases i.e., totally 28 compounds from our earlier research work. A comparative study for two subclasses of coumarins by using various CADD (online and offline) softwares. Computational calculations and predictions of important molecular properties suggest that among the two sub classes of coumarin derivatives, coumarin Schiff bases could be further improved to provide biologically active...
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Posted by admin on Jun 30, 2020 in |
The recent work is based on the extraction and purification of natural gum from the bark of plant Terminalia elliptica (local name – Saaj) and the use of this gum to prepare pulsatile Drug Delivery System of Atenolol for the chronotherapy of cardiovascular diseases. Three formulations CF1, CF2, CF3 of core tablets were prepared by direct compression technique by varying concentrations of crospovidone and evaluated. Formulation CF3 showed the highest 98.71% of drug release after 30 min was selected for press coating. Press coated tablets of Formulation F1 to F5 were prepared by direct compression technique using varying combinations of Saaj gum and Ethylcellulose in the ratio of 1:0, 3:1, 1:1, 1:3 and 0:1 respectively by taking CF3 as core in all. The extracted gum, powder blends, core tablets, and press coated tablets all were evaluated for their physicochemical properties. From the dissolution study of formulation F1 To F5 it was found that F2 having 3:1 combination of Saaj gum and EC shows a significant lag time of around...
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Posted by admin on Jun 30, 2020 in |
The folk population of Gurguripal has mycophilic inclination, and wild mushrooms play a significant role in sustaining their livelihood. Explorative survey work was undertaken to document the ethnomycological knowledge of wild mushrooms occurring in forest areas of Gurguripal. In the present study, 166 informants from 9 villages were interviewed and information was collected through semi-structured questionnaires and interaction based on local name, edibility, medicinal applicability, preparation, and mythological beliefs among native tribal communities of this region. Santal, Munda, and Sabar are dominating schedule tribes in consuming wild edible mushrooms as food or dietary supplement. A total of 23 predominant mushroom species belonging to 16 families were screened. Among them, 19 species were effectively used against different human ailments by the traditional healers. In particular, Termitomyces heimii, Pleurotus ostreatus, Auricularia auricula, and Ganoderma lucidum have shown higher use values and manifold nutraceutical potentials. An Amanitaceous mushroom, namely Amanita bisporigera has been reported the first time herein as edible and recently sold in local markets. The present study enlightens the exploration...
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Posted by admin on Jun 30, 2020 in |
Feronia limonia (F. limonia) is an underutilized edible fruit commonly known as kaitha. The study was performed to compare the effect of three solvents at different concentrations on antioxidant activities of F. limonia fruit. Fruits were extracted in different solvents viz., ethanol, methanol, and acetone at concentrations of 50%, 70%, and 90%. Each extract was analyzed for total phenol and flavonoid content and their antioxidant activities such as Free radical scavenging activity (DPPH), Ferric reducing antioxidant power (FRAP), Metal chelating activity and reducing capacity (RC). The results indicate that 70% aqueous acetone works best for the extraction of TPC (35.60 mg GAE/g), TFC (31.69 mg QCE/g), and other antioxidant activities. The phenol and flavonoid content showed a significant correlation with antioxidant activities. The findings of the study suggested that F. limonia fruit is a good and cheap source of natural antioxidant which can serve as a functional food. The fruit possesses potent enormous health benefits and thus may be used in food and pharmaceutical applications....
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