Posted by admin on Oct 31, 2018 in |
Aim: To assess whether Tranexamic acid has any effect in inhibiting degradability of PRF membrane and also to compare the degradability of PRF at different concentrations of Tranexamic acid (200 mg, 150 mg and 50 mg). Material and Methods: The degradability of PRF membrane was compared between various concentrations of Tranexamic acid such as 200 mg, 150 mg, 50 mg against negative control of phosphate buffer solution (PBS). Group 1-PBS (negative control) n = 5, Group 2-PBS containing 200 mg of Tranexamic acid n = 5, Group 3-PBS containing 150 mg of Tranexamic acid n = 5, and Group 4-PBS containing 50 mg of Tranexamic acid n =5. PRF procured from each donor was weighed in a micro weighing machine and they were later dropped in each of the 4 groups of eppendorfs (5 in each group). After 1 week of storing in room temperature, the PRF pieces were retrieved and percentage of remaining PRF was calculated. ANOVA and post hoc tests were used to statistically compared this data...
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Posted by admin on Oct 31, 2018 in |
Background: Dashamoola is a group of ten drugs i.e. Bilva (Aegle marmelos (L.) Corrêa), Patala (Stereospermum suaveolens (Roxb.) DC.), Agnimantha (Clerodendrum phlomidis L.f.), Shyonaka (Oroxylum indicum (L.) Benth. ex Kurz), Gambhari (Gmelina arborea Roxb.), Bruhati (Solanum nigrum L.), Gokshura (Tribulus terrestris L.), Kantakari (Solanum xanthocarpum Schrad. & H. Wendl.), Prishniparni (Uraria picta (Jacq.) DC.), Shalaparni (Desmodium gangeticum (L.) DC.) part used are moola of all the drugs. Dashamoola kwatha choorna is made use for parisheka in the management of spastic cerebral palsy in children. Aim: To standardize Dashamoola kwatha choorna. Materials and Methods: Physico-chemical studies like Loss on drying, acid insoluble ash, total ash, water soluble ash, alcohol soluble extractive, water soluble extractive and HPTLC were carried out as per the WHO guidelines, Indian Pharmacopoeia and Ayurvedic Pharmacopoeia. Conclusion: Standar-dization tests done on Dashamoola kwatha choorna helped in authenticating and ensuring the quality of the...
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Posted by admin on Oct 31, 2018 in |
Objective: To detect the prevalence of Plasmid resistant AmpC β-lactamases gene in clinical isolates of gram negative organisms from UTI patients which produce resistance against multiple antibiotics. The gene coding for AmpC β-lactamases is also present in E. coli & Klebsiella species was not expressed because due to lack of promoter region, but the transfer of chromosomal genes to plasmids allows the expression of AmpC β-lactamases that hydrolyze the β-lactam ring, which has greater impact on resistance against multi-drug antibiotics, is a significant problem around the world. Methods: Among 20 non-repetitive clinical isolate of each Escherichia coli and Klebsiella pneumoniae, examined for identification and characterization of urine cultures based on morphological, biochemical tests, antibiotic resistant pattern, modified-disc method and detection of AmpC gene by plasmid identification by agarose gel electrophoresis and amplification of AmpC gene by PCR techniques. Results: The study detects the prevalence of AmpC gene primarily by modified disc inducer method as well as conformational molecular analysis by PCR amplification techniques. AmpC prevalence was observed in both...
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Posted by admin on Oct 31, 2018 in |
Objective: Pyrostegia venusta (Ker Gawl.) Miers, Bignoniaceae, is native to the Brazilian Cerrado and popularly known as “cipó-de-são-joão”. In Brazilian folk medicine, the flowers of P. venusta are used as a general tonic and a treatment for diarrhea, vitiligo, cough, and common infections and inflammatory diseases of the respiratory system. Nevertheless, there are still no studies on its possible anti-inflammatory and analgesic effects. Methods: The P. venusta methanolic and pet. ether extract was used to evaluate the anti-inflammatory and analgesic effects in carrageenan-induced paw edema and anti analgesic activity effect in hot plate method. Results: Stem extracts of Pyrostegia venusta demonstrated the analgesic activity at dose of 50 mg/kg body weight. At the end of one-hour percent analgesia induced by petroleum ether extract is 26.34% and that by total methanolic extract is 40.69%. The total petroleum ether extract produced 43.10% inhibition of paw edema, methanolic extract showed 54.31% inhibition of paw edema. Both the extracts had comparable activity. Conclusions: Hence it revealed that Pyrostegia venusta stem extracts had potent...
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Posted by admin on Oct 31, 2018 in |
Objective: The aim of this pilot study was to assess the effect of processed Nigella Sativa (N. Sativa) on oligomenorrhea and amenorrhea in patients with Polycystic Ovarian Syndrome (PCOS). Materials and Methods: Ten women diagnosed with PCOS, having oligo-amenorrhea, participated in this study. The National Institutes of Health (NIH)’s criteria were used for the diagnosis. The patients, between 18 to 38 years old, were treated with 2 g/day of encapsulated processed N. Sativa for 16 weeks. This study compared menstruation habits before and after the medication. A series of metabolic and hormonal investigations was done at the beginning and the end of the study. Participants did not take any other medications. Monthly visits were done to assess the treatment. The effects of N. Sativa on the menstrual cycle was evaluated by four criteria: menstruation occurrence, menstruations intervals, menstruation severity and menstruation duration. The blood test results were analyzed using Stata version 13. Results: The average duration of menstruation and the ratio of cycle per month significantly increased during a...
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