Posted by admin on Jul 31, 2016 in |
Nurses being one of the important members of the healthcare team, play a significant role in providing care and education. Current effective treatments for asthma are in the form of metered-dose inhalers. An effective control is achieved only when the patient is comfortable to use the metered-dose inhaler device correctly. This study was therefore planned to evaluate their knowledge and to assess the effect of a training programme in a tertiary healthcare facility. The aim of the study is to evaluate the effect of education intervention on nurses, knowledge of asthma and metered-dose inhaler technique. This was a pre and post intervention study which involved 45 second year B.Sc nursing students of BMCRI, Bangalore. Pre test consisted of self administered questionnaire about asthma knowledge and demonstration of inhaler technique using pMDI (pressurized metered-dose inhaler). After this, education intervention was given which was followed by a post test. The total mean percentage score of asthma knowledge increased significantly from 63% to 85.5% after education intervention. pMDI demonstration was very poor...
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Posted by admin on Jul 31, 2016 in |
Evidence implicates hyperglycemia induced oxidative stress as a key factor in the pathogenesis of both microvascular and macrovascular complications in the body. Our main objective behind this study was to explore the beneficial effect of Caesalpinia bonducella seed kernel extract on Streptozotocin-induced hyperglycaemia and oxidative damage in rats. Rats were made hyperglycemic by single intravenous injection of Streptozotocin 40mg/kg of body weight. Hyperglycemic rats treated with extract in three different doses of 200, 400 and 600 mg/kg of body weight orally for 21 days shows a significant decrease in blood glucose, HbA1c, free amino groups whereas an increase in serum insulin level, liver glycogen contents with a significant improvement in glucose tolerance. Furthermore, above extract supplementation significantly decreases the pancreatic thiobarbituric acid-reactive substances levels along with an increase in superoxide dismutase, catalase and glutathione contents in pancreatic tissues in treatment groups when compared with control hyperglycemic rats. Treatment with above extract has lessened the severities of degenerative changes in pancreas and also in the liver tissues as compared to...
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Posted by admin on Jul 31, 2016 in |
Aim: To rationalize the macroscopial, anatomical and physico- chemical studies on leaves of Ficus benghalensis (Maraceae). Materials & methods: The crude ethanolic extract of leaves of Ficus benghalensis (Maraceae) was using Physico-chemical parameters, and Preliminary photochemical investigation (TLC, HPTLC, & Column Chrmatography). Results and conclusion: An attempt had been made to highlight this folk herbal medicine through dried crude samples anatomically and physico chemically. TLC fingerprint and HPTLC were carried out and the salient macroscopial qualitative and quantitative parameters were reported. These studies will provide referential information for correct information and help in checking adulteration in market sample...
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Posted by admin on Jul 31, 2016 in |
Oxidative stress appears to be an early event involved in the pathogenesis of Alzheimer’s disease. The present study was designed to investigate the neuroprotective effects of isorhamnetin (IRN) against amyloid beta 25-35 (Aβ 25-35)-induced memory impairment and oxidative damage in rats. Memory task was assessed using Y-arm maze and it revealed the impairment in spatial memory. The IRN treated rats showed improvement in memory task. Aβ 25-35 induced animals also exhibited increase in hydrogen peroxide (H2O2), Monoamine oxidase activity (MAO) and decrease in choline acetyltransferase (ChAT) activity. It also enhanced the expression of inducible nitric oxide synthase (iNOS) and proinflammatory cytokine, IL-β whereas all these abnormalities were reduced significantly in IRN treated rats showing the neuroprotective effect of IRN against Aβ 25-35 induced Alzheimer’s disease (AD). Thus, IRN may be a potential therapeutic agent for Alzheimer’s...
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Posted by admin on Jul 31, 2016 in |
A new physiologically active compound E-2-((2-amino pyridine-3-yl) methylene amino)ethane thiol derived from the condensation of Cysteamine and 2-amino Pyridine 3-Carbaldehyde was synthesized and characterized by spectral techniques like IR, UV-Vis,1H- NMR, TG-DTA, ESR, CHN analyses. The complexes were further screened for their biological activity at Nishka labs and Nickel and Cobalt complexes were found to be potent antibacterial agents. From the above analysis it was found that the ligand behaves as a neutral ligand with N: N: S:N:N donor sequence for octahedral...
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