Posted by admin on Dec 31, 2015 in |
Herbal medicine, rather than merely curing a particular disease, aims at returning the body back to its natural state of health. Vitex negundo Linn. known as Sambhalu in Unani medicine belongs to family Verbenaceae. It is a large aromatic shrub distributed throughout India. It has been used since ancient times as a female remedy in Unani medicine. It is a well known plant because of its two main properties i.e. its use in female disorders specially disorders linked with female reproductive system and decreasing sexual desire. It is also used in other problems like roots and leaves used in eczema, ringworm and other skin diseases, liver disorders, spleen enlargement, rheumatic pain, gout, abscess, backache; seeds used as vermicide. It is also used to control population. This review is an attempt to highlight its therapeutic uses especially in females mentioned in Unani medicine as well as phytochemical and pharmacological...
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Posted by admin on Dec 31, 2015 in |
Studies reported from Ethiopia depict poor health outcomes and management of diabetes cases and low patients’ adherence to recommended regimens including medications. Among factors determining adherence to medications that are amenable to interventions are patient perceptions to their recommended medications. This study thus aimed to assess adherence to anti-diabetic medications and determinant factors including medication related beliefs among type 2 diabetic patients attending their treatment in primary healthcare centers of Addis Ababa, Ethiopia using standardized measures. Methodology: A facility-based cross-sectional study design was followed to assess study participants recruited from among type 2 diabetic patients attending their treatment in three health centers in Kirkos Sub City, Addis Ababa from April to June, 2013. For the assessment interviewer administered structured questionnaires based on standardized measures such as the 8-item Morisk’s Medication Adherence Scale (MMAS) and the specific Belief about Medications Questionnaire (BMQ) were used. Result: A total of 155 study participants, all of whom were on oral hypoglycemic agents were involved in the study among whom 53.5% were male and...
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Posted by admin on Dec 31, 2015 in |
Over the past few decades, the pursuit and exploration of nanotechnology is likely to have a significant impact on the drug-delivery system. This technology can be envisioned as playing a major role in revolutionizing the future of novel drug delivery system. Nanoparticles (NPs) are one of them which have many potential applications in clinical medicine and research. The encapsulation of therapeutic drugs in the form of nanoparticles shows advantageous effect over their corresponding drugs such as increases drug efficacy, specificity, tolerability and therapeutic index. The current review article focuses on the different nanoparticulate drug-delivery systems including nanoerythrosomes, Superparamagnetic nanoparticles, liposomes, Quantum dots, ceramic nanoparticles and dendrimers as well as their applications in different...
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Posted by admin on Dec 31, 2015 in |
objectives: Nelumbo nucifera Gaertn (Nelumbonaceae) known by numerous common names including Indian lotus, sacred lotus, bean of India, or simply lotus is one of the most important medicinal plants. In this review there is discussion about therapeutic potential of the different parts of the plant (leaves, seeds, flower, and rhizome) which can be used in traditional system of medicine. This review also describes various compounds isolated from different parts of the plant and therapeutic benefits derived from those phytocontituents. The aim of this review is to summarize the pharmacological, phytochemical and therapeutical knowledge of Nelumbo nucifera Gaertn. Key findings: The pharmacological studies have shown that N. nucifera possesses various pharmacological activities like anti-ischemic, antioxidant, anticancer, antiviral, antiobesity, lipolytic, hypocholestemic, antipyretic, hepatoprotective, hypoglycemic, antidiarrhoeal, antifungal, antibacterial, anti-inflammatory and diuretic activities. Several different types of compounds have been derived from this plant belonging to different chemical groups, including alkaloids, flavonoids, glycosides triterpenoid, etc., with own therapeutic impact. So the pharmacological effects and various active ingredients of different parts of N. nucifera...
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Posted by admin on Dec 31, 2015 in |
Aim: The present study evaluated the anti-diabetic, anti-hyperlipidimeic, antioxidant activities and renal protective effect of aqueous extract from Ganoderma. lucidum fruiting bodies in streptozotocin induced diabetic rats. Material and Results: Qualitative and quantitative phytochemical analysis for G. Lucidum aqueous extract showed the Presence of high concentration of tannins content. Thin layer chromatography (TLC) revealed the presence one tannin spot which high performance liquid chromatography (HPLC) analysis confirmed that the tannin compound is tannic acid. Extracted tannic acid showed highly antioxidant activity in vitro. Two doses of the extract were administered intraperitoneally. Tannic acid significantly decrease blood glucose levels and significant increase in serum insulin in addition, it improved serum lipid profile in diabetic rats compared to untreated diabetic group. Results: Showed that tannic acid also had potent antioxidant activity in vivo, as it significantly decreased MDA while GSH and GPx in erythrocytic and renal tissues were significantly increased. Histopathological examination of kidney tissue tannic acid treated rats showed mild glomerular atrophy and minimal tubular affection with noticeably dilated blood...
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