Posted by admin on Dec 31, 2024 in |
The aim of this paper is to give a systematic overview on the morphology, ethnobotanical uses, phytochemistry and pharmacological activities of Anogeissus latifolia. It focuses to identify the research gap and further proceed to experimental studies. It may also help out the researcher for further detailed studies. A systematic search criterion of literature was carried out by computing Google scholar, Pub med, NCBI, open access peer reviewed journals and web of science including some unpublished sources. The plant is known to possess wide range of pharmacological activities like Anthelmintic, Thrombolytic, Antiasthmatic, Anticonvulsant, Anticancer, Antidiabetic, Antibacterial, Antipyretic, Antioxidant, Antiulcer, Analgesic, Anti-inflammatory, Hepatoprotective and Wound healing activity. Limited numbers of phytoconstituents were reported like tannins, triterpenoids, ellagic acid, monosaccharides, β- sitosterol from the plant that shows biological activities with diverse ethnobotanical uses. The present review also explores the traditional medicinal uses of the tree, highlighting its role in treating various ailments and wide use of its gum in pharmaceuticals, food processing and...
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Posted by admin on Dec 31, 2024 in |
Grafting polymerization is a process in which polymer chains are covalently bonded (grafted) onto a backbone polymer, leading to the formation of a new material with enhanced properties or functionalities. This process involves the attachment of polymer chains (known as “graft chains” or “grafts”) onto the surface or within the bulk of the substrate material. Polysaccharides have numerous applications in various industries, including food, pharmaceuticals, cosmetics, and biotechnology. They are used as thickeners, stabilizers, emulsifiers, gelling agents, and drug delivery systems due to their biocompatibility, biodegradability, and functional properties. Flavonoids are a group of polyphenolic secondary metabolites found in plants, fruits, and vegetables. They show a wide range of health benefits. They have gained interest recently due to their possible benefits for human health, especially their antioxidant, antiviral, antiallergic, anti-inflammatory, and anticancer characteristics. Flavonoid-grafted polysaccharide-form complexes generate synergistic effects, such as enhanced physical, chemical, and functional properties. Therefore, they show great potential for applications in food, cosmetics, and medicine. Structural characterization methods of the graft products, including FTIR, NMR,...
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Posted by admin on Dec 31, 2024 in |
This study investigates the diagnostic utility of Diffusion Weighted Imaging (DWI) and Apparent Diffusion Coefficient (ADC) values in evaluating intracranial lesions. A cross-sectional analysis of 44 patients was conducted, examining age and gender distribution, histopathological types, and grades of brain tumors. The highest proportion of individuals (22.7%) was within the 0-10 age range, with males comprising 56.8% of the sample. The study focused on supratentorial and infratentorial lesions, categorized by WHO grades, highlighting that Grade IV lesions were most common in both regions. High-grade tumors (WHO Grade III and IV) demonstrated lower ADC values, indicating restricted diffusion, while non-neoplastic conditions such as arachnoid and epidermoid cysts exhibited higher ADC values, reflecting increased diffusion. The presence of perilesional edema was more frequent in higher-grade tumors, underscoring their aggressive behavior and impact on surrounding brain tissue. Diffusion restrictions were significant in Grade IV lesions, with both partial and complete restrictions observed. The Receiver Operating Characteristic (ROC) curve analysis revealed an Area under the Curve (AUC) of 0.70, indicating that DWI possesses...
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Posted by admin on Dec 31, 2024 in |
Objectives: The anti-inflammatory activity of powdered almond gum (Prunus dulcis) was studied by using HRBC membrane stabilizing method and the bioactive compounds which are responsible for anti-inflammatory activity was analyzed by using FTIR analysis. Methods: To study the in-vitro anti-inflammatory activity Human red blood cell (HRBC) membrane stabilization method has been used and for identification of functional groups Fourier Transform infra-red spectroscopy was used. Result and Conclusion: Almond gum resin serves as a good anti-inflammatory agent due to the presence of saponins, steroids, terpenoids and xylan which were identified from FTIR...
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Posted by admin on Dec 31, 2024 in |
Lung cancer (LC) represents a significant global contributor to mortality, particularly for those between the ages of 40 and 50. Additional evidence for this predicament comes from the yearly rise in new LC cases and the disease’s dismal 5-year survival rate of fewer than 15%. Even though smoking has been linked to a significant portion of Lung Cancer cases, a sizable number of non-smokers also contract the condition, raising the possibility that LC development may have hereditary and epigenetic roots. The genome only has about 1% of coding regions. As a result, scientists have studied the genome’s noncoding region and discovered that noncoding RNAs are crucial to the etiology of lung cancer. In more detail, lncRNAs and miRNAs have been extensively investigated over several decades of research. The function of miRNAs in post-transcriptional gene regulation is widely known and understood. It has also been demonstrated that the antagonistic interaction between lncRNAs and miRNAs further regulates gene expression in both healthy and disease situations, including Lung Cancer. A circular RNAs...
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