Posted by admin on Jun 30, 2025 in |
Background: The study assesses pharmacological management of CAD in a tertiary care center, focusing on medication adherence and quality of life (QOL) among hypertensive female patients. Materials and Methods: A prospective observational study conducted at LPS Institute of Cardiology, GSVM Medical College, Kanpur, included 140 diagnosed CAD patients between September 2021 to November 2022. Results: Among 140 participants, 55 patients (39.3%) presented with Acute Coronary Syndrome (ACS): 35 with STEMI and 20 with NSTEMI/UA. The remaining 85 patients had stable angina, underwent diagnostic coronary angiography, or were admitted for post-intervention follow-up, indicating a broader representation of CAD spectrum in clinical settings. The age group 61–70 years was most affected (32.86%). Hypertension (64.3%), diabetes (48.6%), and smoking (29.3%) were the major risk factors. Statins (94.29%), clopidogrel (89.29%), aspirin (86.43%), beta-blockers (60%), and ACE inhibitors (53.57%) were the most prescribed medications. The analysis of QOL domains showed a positive association between medication adherence and physical, psychological, social, and environmental well-being. Conclusion: Adherence to evidence-based pharmacological therapy was high, but underutilization of...
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Posted by admin on Jun 30, 2025 in |
Background: The Gonadal Arteries most commonly arise from the abdominal aorta at the level of the second lumbar (L2) vertebra, supplying the testes and ovaries. The gonadal arteries variations are commonly seen in males on right side however there are few instances where there is variation in ovarian arteries seen in females which could be of importance. Aim of the Study: To re-evaluate the origin and courses of gonadal arteries in human cadavers and explain the developmental anatomy and its clinical significance. Materials and Methods: During routine educational dissection of 24 cadavers in the Department of Anatomy, K.A.P.V. Government Medical College, Trichy, the origin and course of gonadal arteries were observed. I found the variants in 2 female cadavers aged over 60 years. Results: The present study showed variation in the origin of ovarian arteries in 2 female cadavers (8.33%) out of 24 cadavers. I observed, a rare anatomical variant of left ovarian arteries were found, originating from the left accessory renal arteries, just below and behind the left...
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Posted by admin on Jun 30, 2025 in |
Acne vulgaris is a multifactorial skin disorder of pilosebaceous unit which majorly affects teenagers, but it can continue into adulthood and cause aesthetical as well as psychological problems. This review article enlightens the knowledge related to cause and treatment of acne vulgaris. Several factors which are involved in the development of acne vulgaris are hormonal activity, sebum production, follicular epidermal hyperproliferation, colonization with Propioni-bacterium acnes (P. acnes) and inflammation. There are several treatment methods available for acne, although some new therapeutic agents have been introduced during the last few years; synthetic drugs still remain the best option in the treatment of acne. However, rapid appearance of antibiotic resistance and high re ocurrence rates have led to a search for alternatives in nature. The use of herbal drugs in prevention and treatment of acne vulgaris nowadays increased because of their efficiency, availability and lesser side effects than synthetic drugs. Some common used topical herbal remedies with significant anti-inflammatory activities antimicrobial activities have mentioned in this review article include tea tree...
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Posted by admin on Jun 30, 2025 in |
Diabetes is a multifaceted metabolic disorder that impacts individuals worldwide, and delayed wound recovery is a prevalent symptom of diabetes. There is a plethora of methods available now to heal these wounds. Since, chronic inflammation and untreated stages may lead to amputation and death. So, their consequences may cause a patient’s financial strain. However, this review focuses on the most recent formulation, such as miRNA, biomarkers, exosomes, leucine-rich glycoprotein, neutrophils, pro-inflammatory (M1) macrophages, pro-remodeling (M2) macrophages, sustained activation of neutrophils, endothelial progenitor cells, Scaffold, biofilms, carriers, fibers, mats, and antibiotic management for diabetic wound treatment. We discussed their roles as well as therapy plans for managing diabetic wounds with the latest...
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Posted by admin on Jun 30, 2025 in |
Background: Intravascular lithotripsy (IVL) is an innovative method for treating heavily calcified coronary and peripheral lesions. It employs acoustic shock waves to create microfractures in calcified plaques, facilitating stent placement and improving vessel compliance. Objective: To assess the efficacy, safety, and potential applications of IVL in hypertensive patients with calcified coronary lesions, while exploring its diagnostic and therapeutic capabilities. Methods: A thorough review of the latest advancements and studies on IVL, with a focus on its use in hypertensive patients. Key studies, including the Disrupt CAD series, were analyzed for procedural success, safety, and clinical outcomes. The integration of IVL with imaging techniques such as intravascular ultrasound (IVUS) was also investigated. Results: IVL has shown high procedural success rates and minimal complications in treating calcified coronary and peripheral lesions. Studies have reported significant luminal gain post-IVL, with minimal residual stenosis. The Disrupt CAD studies confirmed the safety and efficacy of IVL, with minimal adverse events and substantial calcium fracture in treated lesions. IVL’s effectiveness in managing specific clinically significant...
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