Posted by admin on Jun 30, 2024 in |
Ethnogynaecology is a young field of study that emphasize how indigenous people and local healers manage gynecological conditions in females. The goal of the current study was to record in-depth information about Ethnogynaecology in a previously unexplored region of Haryana. In the year 2022, a floristic and ethnomedicinal survey was conducted in Haryana, India in rural areas of Gurugram district. The present study identified forty plant species with twenty-seven families for treatment of various gynecological disorders. The most frequently used plant parts for herbal preparations were roots followed by leaves, fruit, bark, seed, whole plant, stem, buds, and bulb. The ethno-gynecological significance of medicinal plants in India provides a fertile ground for further scientific investigation to assess their potential, isolate bioactive compounds, and subsequently develop medications for the widespread gynecological health problems experienced by women...
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Posted by admin on Jun 30, 2024 in |
The increased use of antibiotics and the rise of antibiotic resistance among microorganisms pose significant public health concerns. While several herbal drugs have been validated for their antimicrobial activity, identification of additional antimicrobial agents is necessary. The Unani system of medicine comprises numerous herbs and formulations used for treating various infections. Arq e Ajeeb (AA) is one such formulation, historically utilized during epidemics to address conditions such as cholera (Haiza), tuberculosis (Sil), plague(Taoon), and seasonal fevers. Additionally, AA has been used as an anti-inflammatory and analgesic. This study aimed to evaluate the in-vitro antimicrobial activity of AA on four different bacteria, considering antibacterial properties demonstrated by its ingredients. The antibacterial activity of the test sample was evaluated using the minimum inhibitory concentration (MIC) method. Bacterial strains (P. aeruginosa, E. hirae, E. coli, S. mutans) were inoculated in 100μl sterile MHB broth. A test sample underwent double dilutions ranging from 100 to 0.048828mg. Ciprofloxacin (0.1%) served as the standard antibiotic. The plates were incubated at 32.5 ± 2.5°C for 24...
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Posted by admin on Jun 30, 2024 in |
This research investigates the anti-inflammatory potential of Azadirachta indica-loaded microsponges gel, presenting a novel therapeutic approach. The microsponges gel, formulated with Azadirachta indica, aim to enhance drug delivery efficiency for improved anti-inflammatory effects. The microsponges gel is formulated using Carbopol 934P (1% w/v) to optimized encapsulated microsponge. Prepared formulation was evaluated for pH, spreadability, viscosity, and ex-vivo drug deposition study. Characterization studies, in-vitro release assessments, and anti-inflammatory assays contribute to a comprehensive evaluation of the formulated microsponge gel. Preliminary results demonstrate successful formulation of Azadirachta indica-loaded microsponge gel. Characterization studies confirm the structure and composition. In-vitro release studies reveal sustained drug release, and initial anti-inflammatory assays indicate promising activity. This study underscores the potential of Azadirachta indica-loaded microsponge gel as a promising anti-inflammatory therapeutic strategy. The formulation’s sustained release profile and demonstrated efficacy in anti-inflammatory assays pave the way for further investigation and potential clinical...
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Posted by admin on Jun 30, 2024 in |
Food safety is at risk from several variables, including physical, chemical, and biological risks. In this context, biological risks are of utmost significance. The bacteria among them are crucial in producing food deterioration and food-borne illnesses. Additionally, a novel strategy has been applied in recent years that relies on pro-biotic and post-biotic to inhibit the increase of pathogenic microbes and the mediated corruption they cause because of their potent antimicrobial characteristics. The word “postbiotic” designates soluble elements produced by live bacteria or released following bacterial lysis, including enzymes, peptides, teichoic acids, muropeptides produced by peptidoglycans, polysaccharides, cell surface proteins, and organic acids. Postbiotics have a significant potential to be employed in the pharmaceutical, food, and nutraceutical sectors to improve health and disease prevention due to a variety of signaling substances that may have antioxidant, immune-modulatory, anti-inflammatory, antihypertensive, and antiproliferative effects. The current investigation was to determine the antagonistic potential of the secreted probiotic filtrates, also known as postbiotics, generated from some microorganisms against pathogenic microbes such as Candida albicans,...
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Posted by admin on Jun 30, 2024 in |
Natural products have achieved approval globally for assisting healthcare and also disease obstruction. Alkaloids are an important group of diversely distributed, chemically, biologically and commercially significant natural product which have various organic compounds that give different pharmacological activities. The most important and initial step in medicinal plant is extraction because the bioactive compounds need to be extracted from the plant and various techniques are involved like ultrasound assisted extraction, microwave assisted extraction, supercritical fluid extraction, solid phase extraction, liquid-liquid extraction, enzyme assisted extraction etc. alkaloids are obtained from plant, bacteria, fungi and animals. In this paper we gather information about plant alkaloids, classification of plant alkaloids with their different types of extraction techniques, chemical structure and biological sources. Natural products have achieved approval globally for assist healthcare and also disease obstruction. Alkaloids are an important group of diversely distributed, chemically, biologically and commercially significant natural product which have various organic compounds that give different pharmacological activities. Wide range of alkaloids is present in different parts of plants. Different parts...
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